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Neuroimaging in frontotemporal dementia
International Review of Psychiatry, 2013The term frontotemporal dementia (FTD) refers to a group of neurodegenerative disorders that are associated with atrophy of the frontal and temporal lobes, and present clinically with impairments of behaviour or language. Three main subtypes are described, behavioural variant FTD (bvFTD) and two subtypes of the language presentation (known as primary ...
Jonathan D, Rohrer, Howard J, Rosen
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Continuum
This article discusses frontotemporal dementia (FTD) syndromes using a simplified framework of three core syndromes, including details on their pathology and unique genetic variations.FTD includes at least seven major clinical syndromes. The three core syndromes are behavioral variant FTD and two forms of progressive aphasia, commonly referred to as ...
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This article discusses frontotemporal dementia (FTD) syndromes using a simplified framework of three core syndromes, including details on their pathology and unique genetic variations.FTD includes at least seven major clinical syndromes. The three core syndromes are behavioral variant FTD and two forms of progressive aphasia, commonly referred to as ...
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Survival in frontotemporal dementia
Neurology, 2003To establish survival in patients with pathologically confirmed frontotemporal dementia (FTD) and to determine whether clinical or pathologic subtype affects prognosis.The authors reviewed the presenting clinical features of 61 patients with dementia and pathologically confirmed FTD studied in Sydney (n = 31) and Cambridge (n = 30) over a 10-year ...
J R, Hodges +4 more
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The genetics of frontotemporal dementia
2008Publisher Summary This chapter emphasizes that frontotemporal dementia (FTD) is the second most common form of primary degenerative dementia after Alzheimer's disease (AD). The onset of the disease is most commonly in middle age between 45 and 65 years.
Pickering-Brown, Stuart, Hutton, Michael
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Genetics of Frontotemporal Dementia
Current Neurology and Neuroscience Reports, 2016Frontotemporal dementia (FTD) is the second most common cause of dementia following Alzheimer's disease (AD). Between 20 and 50% of cases are familial. Mutations in MAPT, GRN and C9orf72 are found in 60% of familial FTD cases. C9orf72 mutations are the most common and account for 25%. Rarer mutations (
Diana A, Olszewska +3 more
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Depression in Frontotemporal Dementia
Psychosomatics, 2009The authors describe mood abnormalities seen in a case series of patients with frontotemporal dementia (FTD).Authors provide a structured review of outpatient and inpatient charts of FTD patients.Three distinct depressive syndromes were identified: The first corresponds to DSM-IV major depression.
David M, Blass, Peter V, Rabins
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Frontotemporal dementia: A review
Journal of the International Neuropsychological Society, 2002This review summarizes the clinical, imaging, and pathological features of frontotemporal dementia (FTD). Clinicians have become increasingly sensitive to FTD in the differential diagnosis of Alzheimer's disease. Clinical subgroups of FTD patients have been recognized, including patients with progressive non-fluent aphasia, semantic dementia, and ...
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Parkinsonism in frontotemporal dementias
2019Frontotemporal dementia is a clinically and pathologically heterogeneous group of neurodegenerative disorders, with progressive impairment of behavior and language. They can be closely related to amyotrophic lateral sclerosis, clinically and through shared genetics and similar pathology. Approximately 40% of people with frontotemporal dementia report a
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