Results 211 to 220 of about 315,827 (302)

Powering Neurology Drug Development Trials to Reduce False Negative Results

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Sensitive and reliable measurement of therapeutic outcomes in neurology drug trials remains challenging. Clinical rating scales and their total scores are often considered the gold standard and used as primary efficacy endpoints in studies because of their acceptance by the clinical community and regulators.
Hiromasa Mori, Stig Johan Wiklund, Vikram Ramanarayanan, Fatta B. Nahab   +3 more
wiley   +1 more source

Utilization of transcranial direct current stimulation for neuromodulation in frontotemporal dementia. [PDF]

Ind Psychiatry J
Sinha SS, Ashwin JV, Singh N, Shahi MK, Kar SK, Singh B.   +5 more
europepmc   +1 more source

Early neurodevelopmental outcome in newborns with mild hypoxic‐ischaemic encephalopathy

Developmental Medicine &Child Neurology, Volume 68, Issue 9, Page 1261-1268, September 2026.
Abstract Aim To describe the natural history of newborn children with mild hypoxic‐ischaemic encephalopathy in the first year of life. Method This was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian
Domenico M. Romeo, Chiara Arpaia, Angelo Di Malta, Elisa Pede, Grazia Maria Cicala, Daniela Ricci, Francesca Serrao, Eugenio Mercuri, Claudia Brogna, Mild Encephalopathy Regional Network*, Giovanni Vento, Chiara Cafforio, Eleonora Scapillati, Roberta Arena, Francesca Gallini, Vita Augusta, Andrea Guzzetta   +16 more
wiley   +1 more source

Music processing in behavioural variant frontotemporal dementia and Alzheimer's disease: a functional MRI study. [PDF]

Brain Commun
van 't Hooft JJ, van der Zwaag W, Wink AM, Barkhof F, Schaefer RS, Warren JD, Pijnenburg YAL, Tijms BM.   +7 more
europepmc   +1 more source

Protein Biomarkers in Risk and Prognosis of Amyotrophic Lateral Sclerosis

European Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Background Plasma and cerebrospinal fluid (CSF) protein biomarkers in amyotrophic lateral sclerosis (ALS) may provide insight into disease mechanisms and yield clinically useful biomarkers. Methods Overall, 363 proteins in plasma and CSF from 198 patients with ALS and 125 matched controls were profiled using Olink assays.
Lu Pan, Can Hou, Christina Seitz, Caroline Ingre, Åsa K. Hedman, Jose Laffita, Trung Nghia Vu, Yudi Pawitan, Abbe Ullgren, Solmaz Yazdani, John Andersson, Emily E. Joyce, Charilaos Chourpiliadis, Anikó Lovik, Yan Chen, Sebastian A. Lewandowski, Oscar Fernandez‐Capetillo, Myriam Barz, Kristin Samuelsson, Rayomand Press, Fredrik Piehl, Caroline Graff, Anders Mälarstig, Fang Fang   +23 more
wiley   +1 more source

Eating behaviour profiles across the frontotemporal dementia spectrum. [PDF]

J Neuropsychol
Sato Y, Hayashi H, Kakinuma K, Iseki C, Ota S, Katsuse K, Matsubara S, Kawakami N, Kanno S, Morihara K, Nishio Y, Suzuki K.   +11 more
europepmc   +1 more source

TUBA4A Pathogenic Variant Manifesting With Adulthood‐Onset Genetic Myasthenic Syndrome, Myopathy, and Infertility

European Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Objectives TUBA4A pathogenic variants are associated with ALS, frontotemporal dementia, spastic ataxia, spasticity, ataxia, Parkinson's disease, female infertility, macrothrombocytopenia, and myopathy. Four recently reported patients with TUBA4A neonatal/childhood onset myopathy had also a decrement on repetitive nerve stimulation (RNS), but ...
Margherita Milone, Stefan Nicolau, Zhiyv Niu, Teerin Liewluck, Eric J. Sorenson, Xin‐Ming Shen, C. Michael Harper, William J. Litchy   +7 more
wiley   +1 more source

Factors influencing accelerated progression in behavioral variant frontotemporal dementia. [PDF]

J Neurol
Split M, Kunicki ZJ, Ross D, Keszycki R, Prieto S, Manoochehri M, De Vito AN, Appleby B, Hales CM, Onyike C, McMillan CT, Clark D, Irwin D, Knopman D, Galasko DR, Wint D, Roberson ED, Léger GC, Hsiung GR, Heuer HW, Rosen HJ, Grant IM, Mackenzie IR, Litvan I, Kornak J, Kwan J, Rascovsky K, Domoto-Reilly K, Massimo L, Honig LS, Forsberg LK, Tartaglia MC, Mendez MF, Graff-Radford N, Ghoshal N, Ljubenkov P, Darby RR, Barmada S, Weintraub S, Lee S, Sullivan AC, Boxer A, Staffaroni AM, Snyder A, Bozoki A, Pascual B, Dickerson BC, Boeve BF, Huey ED, Barker M.   +49 more
europepmc   +1 more source

Future Prospects of Ultrasound: Role of Low‐Intensity Transcranial Ultrasound Stimulation in the Treatment of Neurological and Psychiatric Disorders

European Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Background Neurological and psychiatric disorders pose a persistent global health burden, with conventional therapies often providing inadequate relief. Transcranial ultrasound stimulation (TUS) has attracted considerable attention as a non‐invasive neuromodulation technique offering high spatial resolution and the distinctive capacity to ...
Yunjie Sui, Mingyue Wei, Robert Chen, Xue Xia   +3 more
wiley   +1 more source