Results 1 to 10 of about 22,079 (225)
Cell & Bioscience, 2018 Background MAPT-AS1, a long non-coding RNA, has not been reported in any previous research about its function in cancers. In this study, we investigated the role of MAPT-AS1 in the progression and paclitaxel resistance in breast cancer, and the ...
Yiyuan Pan +5 more
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Mitochondrial Defects in Fibroblasts of Pathogenic MAPT Patients [PDF]
Frontiers in Cell and Developmental Biology, 2021 Mutations in MAPT gene cause multiple neurological disorders, including frontal temporal lobar degeneration and parkinsonism. Increasing evidence indicates impaired mitochondrial homeostasis and mitophagy in patients and disease models of pathogenic MAPT.
Vinita Bharat +2 more
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Efficacy of mental and physical training on blood pressure and resting heart rate among physically inactive young adults with elevated blood pressure: a randomized controlled trial [PDF]
Scientific ReportsPhysically inactive adults with elevated blood pressure (BP) are at an increased risk of developing hypertension and cardiovascular comorbidity. Lifestyle-based non-pharmacological interventions are therefore essential.
Imtiyaz Ali Mir +4 more
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Rates of lobar atrophy in asymptomatic MAPT mutation carriers
Alzheimer's and Dementia: Translational Research and Clinical Interventions, 2019 Introduction The aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule‐associated protein tau (MAPT) mutation carriers.
Zbigniew K Wszolek +2 more
exaly +2 more sources
Empirical analysis of IPv6 transition technologies using the IPv6 Network Evaluation Testbed [PDF]
EAI Endorsed Transactions on Industrial Networks and Intelligent Systems, 2015 IPv6 has yet to become more than a worthy successor of IPv4, which remains, for now, the dominant Internet Protocol. This is due to the complicated transition period through which the Internet will have to go, until IPv6 will completely replace IPv4. One
Marius Georgescu +3 more
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Frontiers in Aging Neuroscience, 2023 Tau is a microtubule-associated protein with a diverse functional repertoire linked to neurodegenerative disease. Recently, a human tau knock-in (MAPT KI) mouse was developed that may overcome many limitations associated with current animal models used ...
Matthew J. Benskey +7 more
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DNA methylation in Parkinson disease
Анналы клинической и экспериментальной неврологии, 2020 Parkinson disease (PD) is one of the most widespread neurodegenerative diseases in the elderly. It causes motor impairment and the development of non-motor symptoms, which reduce the quality of life and gradually lead to patient disability.
Elena V. Yakovenko +2 more
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Folia Neuropathologica, 2020 Traumatic brain injury (TBI) is the leading cause of death and disability around the world in all age groups. The primary injury of TBI is exacerbated by secondary injury, leading to an increased inflammatory response, cell death and even impairment of ...
Haihai Dong, Haitao Wang, Liang Wang
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Blood MAPT expression and methylation status in Alzheimer's disease
PCN Reports, 2022 Aim This study aimed to investigate the expression levels and methylation status of microtubule‐associated protein tau (MAPT) in the blood of Alzheimer's disease (AD) patients and age‐ and sex‐matched healthy controls. Methods Fifty AD outpatients and 50
Hiroaki Mori +9 more
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Frontiers in Pharmacology, 2021 Background: Ischemic stroke is a common disease with poor prognosis, which has become one of the leading causes of morbidity and mortality worldwide. Astragaloside IV (AS-IV) is the main bioactive ingredient of Astragali Radix (which has been used for ...
Yi-Hua Shi +7 more
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