Results 191 to 200 of about 315,827 (302)
Early-onset frontotemporal dementia misdiagnosed as psychosis: a case from rural Nepal. [PDF]
Shrestha P +4 more
europepmc +1 more source
Passive ASO association with NSC‐EVs enhances neuronal uptake and CNS accumulation. NSC‐EV‐ASOs suppress pathogenic targets in ALS cellular models and, following intranasal administration, delay disease onset and improve motor function in SOD1‐G93A mice. These findings provide proof‐of‐concept evidence supporting NSC‐EVs as a platform for enhancing CNS
Yaochao Zheng +8 more
wiley +1 more source
Distinct brain extracellular vesicle microRNA profiles differ in frontotemporal dementia and Alzheimer's disease. [PDF]
Morgan J +3 more
europepmc +1 more source
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source
Clinical tools to differentiate behavioral variant frontotemporal dementia from phenocopies. [PDF]
Flavell J +7 more
europepmc +1 more source
RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities
RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley +1 more source
Earlier variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), including the original strain, Alpha and Delta, were linked to significant and persistent cognitive impairment. The long‐term cognitive impact of Omicron infection, however, has remained uncertain. This study shows that post‐Omicron cognitive decline is largely reversible,
Min Qiu +15 more
wiley +1 more source
Frontotemporal dementia with right temporal predominance: a clinical comparison with left-predominant FTD. [PDF]
Thompson JC +8 more
europepmc +1 more source
Reclaiming obsessionality: Beyond the obsessive‐compulsive spectrum
Abstract The concept of the obsessive‐compulsive spectrum has exerted a major influence on contemporary psychiatry and contributed substantially to the establishment of the DSM‐5 category of obsessive‐compulsive and related disorders. However, the notion of obsessionality employed within this framework does not necessarily correspond to the classical ...
Toshiyuki Kobayashi
wiley +1 more source
Peripheral immune profiling in frontotemporal dementia. [PDF]
Gamez N +7 more
europepmc +1 more source

