Results 181 to 190 of about 315,827 (302)

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen, Wangzheqi Zhang, Lizhou Song, Yan Liao, Haoling Zhang, Yiyang Xia, Derong Cui   +6 more
wiley   +1 more source

Cellular signatures underlying functional resilience in presymptomatic frontotemporal dementia. [PDF]

Brain
Tsvetanov KA, Malpetti M, Jones PS, Rittman T, Whiteside DJ, Murley AG, Bethlehem R, Paquola C, Premi E, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Levin J, Sorbi S, Otto M, Bertoux M, Lebouvier T, Ducharme S, Butler CR, Le Ber I, Finger E, Tartaglia MC, Masellis M, Synofzik M, Moreno F, Borroni B, Rohrer JD, Rowe JB, Genetic FTD Initiative, GENFI.   +42 more
europepmc   +1 more source

Young Adult Microglial Deletion of C1q Reduces Engulfment of Synapses and Partially Mitigates Cognitive Impairment in an Aggressive Alzheimer's Disease Mouse Model

Glia, Volume 74, Issue 9, September 2026.
Young adult deletion of microglial C1q reduced engulfment of Vglut1+ synapses and mitigated spatial cognitive deficits at 10 months of age in the amyloidopathy Arctic mouse model of AD. Neither fibrillar amyloid plaques nor soluble or insoluble Aβ levels in the hippocampus were affected by young adult microglial loss of C1q despite reduced phagocytosis
Tiffany J. Petrisko, Shu‐Hui Chu, Angela Gomez‐Arboledas, Blossom Zhang, Andrea J. Tenner   +4 more
wiley   +1 more source

Educational attainment and sex modulate clinical outcomes in genetic frontotemporal dementia. [PDF]

Brain Commun
Premi E, Archetti D, Redolfi A, Bracca V, Cantoni V, Iraji A, Calhoun VD, Bellini S, Ghidoni R, Gasparotti R, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Di Fede G, Santana I, Gerhard A, Levin J, Nacmias B, Otto M, Bertoux M, Lebouvier T, Ducharme S, Butler CR, Le Ber I, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Zetterberg H, Rohrer JD, Borroni B, GENetic Frontotemporal dementia Initiative (GENFI), GENetic Frontotemporal dementia Initiative (GENFI) .   +44 more
europepmc   +1 more source

Dementia Risk After Glaucoma Surgery and Medical Therapy: A Multicentre Real‐World Cohort Study

International Journal of Geriatric Psychiatry, Volume 41, Issue 9, September 2026.
ABSTRACT Background and Purpose Glaucoma, a neurodegenerative optic neuropathy and leading cause of irreversible vision loss, shares vascular and neurodegenerative mechanisms with dementia. The 2024 Lancet Commission newly identified visual impairment as a modifiable dementia risk factor.
Lee‐Yuan Lin, Jie‐Syuan Wu, Wei‐Jung Jeng, Chen‐Hsin Tsai, Shu‐Yu Liu, Tsai‐Wei Huang, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +7 more
wiley   +1 more source

Language impairments in behavioural variant frontotemporal dementia: a comparative study with semantic dementia. [PDF]

J Neurol
Savage S, Aung O, Foxe D, Piguet O.
europepmc   +1 more source

Perspectives on Frontotemporal Dementias

The American Journal of Geriatric Psychiatry, 1994
Anand, Kumar, Gary, Gottlieb
openaire   +2 more sources

The Human Subiculum and Its Role in Spatiotemporal Memory and Mental Imagery

Hippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT Traditionally viewed as a mere relay station of the hippocampal formation, the subiculum is emerging as a computational hub of the medial temporal lobe, essential for multiplexed neural representations guiding behavior. While foundational animal research has revealed that its sophisticated cytoarchitecture allows for conjunctive coding of ...
Hye Ja Kang, Maria Jieun Hwang, Ji Sun Kim, Ji Yeon Kim, Marie‐Agathe Crampon de Place, Sang Ah Lee   +5 more
wiley   +1 more source

Machine Learning Prediction of One‐Year Rehospitalization in Dementia: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Patients with dementia have high rehospitalization rates, creating substantial clinical and economic burden. Machine learning (ML) may help predict readmission risk, but its use for clinically relevant outcomes such as rehospitalization in dementia remains limited.
Amirreza Esmaeili, Vahid Saeedi, Leila Kamalzadeh   +2 more
wiley   +1 more source

Frontotemporal dementia and psychiatry [PDF]

International Review of Psychiatry, 2013
Chiadi U, Onyike, Edward D, Huey
openaire   +2 more sources