Results 51 to 60 of about 364,393 (335)

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort

Alzheimer's & Dementia, 2020
Behavioral variant frontotemporal dementia (bvFTD) may present sporadically or due to an autosomal dominant mutation. Characterization of both forms will improve understanding of the generalizability of assessments and treatments.
H. Heuer, Ping Wang, K. Rascovsky, Amy Wolf, B. Appleby, J. Bove, Y. Bordelon, Patrick Brannelly, D. Brushaber, C. Caso, G. Coppola, B. Dickerson, S. Dickinson, K. Domoto-Reilly, Kelly Faber, Jessica Ferrall, J. Fields, Ann Fishman, Jamie C. Fong, T. Foroud, L. Forsberg, Debra J. Gearhart, Behnaz Ghazanfari, N. Ghoshal, J. Goldman, J. Graff‐Radford, N. Graff-Radford, I. Grant, M. Grossman, Dana Haley, G. Hsiung, E. Huey, D. Irwin, David T. Jones, K. Kantarci, A. Karydas, Daniel I. Kaufer, D. Kerwin, D. Knopman, J. Kornak, J. Kramer, Ruth A. Kraft, W. Kremers, W. Kukull, I. Litvan, P. Ljubenkov, I. Mackenzie, Miranda Maldonado, Masood Manoochehri, S. McGinnis, Emily C. McKinley, Mario F. Mendez, B. Miller, C. Onyike, Alexander Y. Pantelyat, Rodney Pearlman, L. Petrucelli, Madeleine Potter, R. Rademakers, E. Ramos, K. Rankin, E. Roberson, E. Rogalski, Pheth Sengdy, L. Shaw, Jeremy A. Syrjanen, M. Tartaglia, N. Tatton, J. Taylor, A. Toga, J. Trojanowski, S. Weintraub, Bonnie Wong, Z. Wszolek, B. Boeve, Howard H. Rosen, A. Boxer, Artfl, Lefftds consortia   +78 more
semanticscholar   +1 more source

The C9ORF72 mutation brings more answers and more questions. [PDF]

, 2013
The clinical, neuropsychiatric and neuroimaging features of patients who carry the important new C9ORF72 mutation are discussed in this special series of Alzheimer's Research & Therapy.
Miller, Bruce L
core   +1 more source

Dissociation of structural and functional integrities of the motor system in amyotrophic lateral sclerosis and behavioral-variant frontotemporal dementia [PDF]

, 2016
Background and Purpose: This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy controls (n=37 ...
Bae, Jong Seok, Burrell, James, Ferguson, Michele, Hodges, John R., Hornberger, Michael, Kiernan, Matthew C., Mioshi, Eneida, Simon, Neil, Tan, Rachel, Vucic, Steve   +9 more
core   +2 more sources

An update on genetic frontotemporal dementia

Journal of Neurology, 2019
Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders, with around 30% of patients having a strong family history. The majority of that heritability is accounted for by autosomal dominant mutations in the chromosome 9 ...
C. Greaves, J. Rohrer
semanticscholar   +1 more source

Delusions in frontotemporal lobar degeneration [PDF]

, 2009
We assessed the significance and nature of delusions in frontotemporal lobar degeneration (FTLD), an important cause of young-onset dementia with prominent neuropsychiatric features that remain incompletely characterised.
Alladi, Arciniegas, Bak, Ballard, Cairns, Catherine J. Mummery, Chan, Clement T. Loy, Elizabeth L. Sampson, Engelborghs, Geroldi, Gregory, Gregory, Hirono, Hodges, Howard, Jason D. Warren, Levy, Martin N. Rossor, McKhann, Mendez, Mendez, Neary, Nick C. Fox, Nitrini, Ogar, Rascovsky, Rohani Omar, Rosen, Scarmeas, Swartz, Tartaglia, Waddington   +32 more
core   +2 more sources

Clinical and Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP‐43 A and B

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Certain frontotemporal lobar degeneration subtypes, including TDP‐A and B, can either occur sporadically or in association with specific genetic mutations. It is uncertain whether syndromic or imaging features previously associated with these patient groups are subtype or genotype specific.
Sean Coulborn, Rhiana Schafer, Ashlin R. K. Roy, Andrzej Sokolowski, Noah G. Cryns, Dana Leichter, Argentina Lario Lago, Eliana Marisa Ramos, Yann Cobigo, Salvatore Spina, Lea T. Grinberg, Daniel H. Geschwind, Maria L. Gorno‐Tempini, Joel H. Kramer, Howard J. Rosen, Bruce L. Miller, William W. Seeley, David C. Perry   +17 more
wiley   +1 more source

Risk assessment of accidental falls in patients taking trazodone, quetiapine, or risperidone for insomnia: A single‐center, case–control study

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 532-537, December 2022., 2022
Abstract Aim No consensus has been reached on the association between the risk of falls and antipsychotic and antidepressant drug use. In this study, we evaluated the risk of falls with trazodone, risperidone, and quetiapine, which are recommended for use at Kanazawa Medical University Hospital.
Yoshihito Shimizu, Masatoshi Taga, Yoshimitsu Takahashi, Yasuhiko Yamamoto, Togen Masauji   +4 more
wiley   +1 more source

Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]

, 2005
In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc, Dermaut, Bart, Kumar-Singh, Samir, Rademakers, Rosa, Theuns, Jessie, Van Broeckhoven, Christine   +5 more
core   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Evaluation of the INECO Frontal Screening and the Frontal Assessment Battery in Peruvian patients with Alzheimer's disease and behavioral variant Frontotemporal dementia [PDF]

, 2016
Background: The physicians often confuse the early symptoms of Frontotemporal dementia (FTD) with Alzheimer dementia (AD), leading to misdiagnosis. There are some cognitive tests to discriminate between AD and behavioral variant FTD (bvFTD), and the ...
Báez Buitrago, Sandra Jimena, Custodio, Nilton, Herrera Perez, Eder, Lira, David, Manes, Facundo Francisco, Roca, María, Torralva, Teresa   +6 more
core   +2 more sources