Results 21 to 30 of about 21,388 (227)

Transcriptomic and Network Meta-Analysis of Frontotemporal Dementias

Frontiers in Molecular Neuroscience, 2021
Frontotemporal lobar degeneration (FTLD), also known as frontotemporal dementia (FTD), results in a progressive decline in executive function, leading to behavioral changes, speech problems, and movement disorders.
Virginie Bottero, Fahed Alrafati, Jose A. Santiago, Judith A. Potashkin   +3 more
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A Genome-Wide Screening and SNPs-to-Genes Approach to Identify Novel Genetic Risk Factors Associated with Frontotemporal Dementia [PDF]

, 2015
Frontotemporal dementia (FTD) is the second most prevalent form of early onset dementia after Alzheimer’s disease (AD). We performed a case-control association study in an Italian FTD cohort (n = 530) followed by the novel SNPs-to-genes approach and ...
Maletta, Raffaele G, S. Bagnoli, Piaceri, I, Bagnoli, Silvia, Cusi, Daniele, Singleton, A, Giaccone, G, Archetti, Silvana, Hardy, J, Binetti, Giuliano, Galimberti, Daniela, Manunta, P, G. Milan, F. Tagliavini, Rubino, E, E. Scarpini, A. Singleton, L. Pinessi, Tagliavini, Fabrizio, Bernardi, Livia, Maletta, Raffaele G., F. D'Avila, Milan, G, Barlassina, C, Benussi, L, Novelli, V, Grassi, Mario, Serpente, M, G. Giaccone, PUCA, Annibale Alessandro, Maletta, RG, Borroni, B, Bruni, Amalia C, Palluzzi, Fernando, B. Borroni, V. Novelli, R. Ghidoni, D. Pepe, Ferrari, Raffaele, Archetti, S, R. Ferrari, Bagnoli, S, Rainero, Innocenzo, Manunta, Paolo, Milan, Graziella, Pinessi, Lorenzo, Piaceri, Irene, Scarpini, Elio, I. Piaceri, Pinessi, L, A. Postiglione, Giaccone, Giorgio, M. Franceschi, Momeni, Parastoo, Galimberti, D, D'Avila, F, Novelli, Valeria, S. Archetti, Ghidoni, Roberta, Franceschi, M, Franceschi, Massimo, D’Avila, F, Serpente, Maria, B. Nacmias, Scarpini, E, M. Grassi, Cusi, D, Padovani, A, F. Palluzzi, M. Serpente, Postiglione, A, Ghidoni, R, R. G. Maletta, Hardy, John, A. C. Bruni, A. A. Puca, E. Rubino, L. Benussi, Postiglione, Alfredo, Glorioso, Nicola, Benussi, Luisa, Rossi, Giacomina, Puca, Annibale A., L. Bernardi, Bruni, AC, Puca, AA, Singleton, Andrew, I. Rainero, Palluzzi, F, Binetti, G, D. Galimberti, Bernardi, L, P. Momeni, PADOVANI, Alessandro, Glorioso, N, Nacmias, Benedetta, N. Glorioso, P. Manunta, A. Padovani, G. Rossi, D. Cusi, Bruni, Amalia C., Grassi, M, Rubino, Elisa, Salvi, Erika, Barlassina, Cristina, Tagliavini, F, Pepe, D, G. Binetti, J. Hardy, C. Barlassina, Pepe, Daniele, Momeni, P., Momeni, P, E. Salvi, Rossi, G, Nacmias, B, BORRONI, Barbara, D'Avila, Francesca, Rainero, I, Salvi, E, Ferrari, R   +121 more
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Living with a diagnosis of frontotemporal dementia:An interpretative phenomenological analysis [PDF]

, 2023
Frontotemporal dementia describes a spectrum of disorders which include behavioural changes, changes to affect, speech difficulties and physical issues.
Robertson, Jane, Gray, Suzanne, Shepherd, Ashley   +2 more
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Total and phosphorylated tau proteins: Evaluation as core biomarker candidates in frontotemporal dementia [PDF]

, 2004
An ever increasing number of patients with neurodegenerative disorders calls for the evaluation of potential diagnostic markers that allow an early diagnosis and an early initiation of specific therapy. Clinical diagnosis of Alzheimer's disease (AD), the
Teipel, S. J., Hampel, H., Harald Hampel, Stefan J. Teipel   +3 more
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Cerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]

, 2010
Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...
Hermann Esselmann, Mirko Bibl, Johannes Kornhuber, Markus Otto, Esselmann, Hermann, Rüther, Eckart, Otto, Markus, Lewczuk, Piotr, Kornhuber, Johannes, Eckart Rüther, Piotr Lewczuk, Brit Mollenhauer, Bibl, Mirko, Wolf, Stefanie, Jens Wiltfang, Mollenhauer, Brit, Wiltfang, Jens, Stefanie Wolf   +17 more
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A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study [PDF]

, 2021
Availability of data and materials: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.Supplementary Information: Additional file 1 of A panel of CSF proteins separates genetic ...
Heller, C, Bocchetta, M, Bergström, S, Castelo-Branco, M, Giaccone, G, Karnath, HO, Bender, B, Miltenberger, G, Jelic, V, Bras, J, Arighi, A, Rohrer, JD, Benussi, A, Santana, I, Indakoetxea, B, Lombardi, G, Levin, J, Masellis, M, Benussi, L, Caroppo, P, Synofzik, M, Afonso, S, Cope, T, Borroni, B, Antonell, A, Seelaar, H, van Minkelen, R, Olofsson, J, Cash, D, Archetti, S, Borrego-Ecija, S, Laforce, R, Convery, R, Tartaglia, C, Fumagalli, G, Galimberti, D, Gabilondo, A, Mitchell, S, Meeter, L, Bessi, V, Black, S, Barandiaran, M, Loosli, S, van Swieten, JC, Gazzina, S, Leitão, MJ, Otto, M, Fox, N, Ghidoni, R, Di Fede, G, Maruta, C, Bargalló, N, Jiskoot, L, Hoegen, T, Ducharme, S, Danek, A, Sanchez-Valle, R, Guerreiro, R, Öijerstedt, L, Freedman, M, Månberg, A, Cantoni, V, Balasa, M, Duro, D, Gasparotti, R, Finger, E, Fenoglio, C, Ferreira, CB, Binetti, G, Díez, A, Almeida, MR, Mead, S, Rowe, JB, Le Ber, I, Frisoni, G, Bruffaerts, R, Andersson, C, Cañada, M, Moreno, F, Nilsson, P, Ferrari, C, Keren, R, Lladó, A, Bartha, R, Graff, C, Greaves, C, Tagliavini, F, Gorostidi, A, Ullgren, A, Butler, CR, Gerhard, A, Langheinrich, T, Vandenberghe, R, Remnestål, J, de Mendonça, A, Sorbi, S, Gauthier, S, Pasquier, F, Anderl-Straub, S   +98 more
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Genetics of dementia: insights from Latin America

Dementia & Neuropsychologia, 2020
. Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are neurodegenerative disorders that result in a significant burden to both patients and caregivers. By 2050, the number of people with dementia in Latin America will increase 4-fold.
Claudia Ramos, David Aguillon, Christian Cordano, Francisco Lopera   +3 more
doaj   +1 more source

A multi-omics dataset for the analysis of frontotemporal dementia genetic subtypes

Scientific Data, 2023
Understanding the molecular mechanisms underlying frontotemporal dementia (FTD) is essential for the development of successful therapies. Systematic studies on human post-mortem brain tissue of patients with genetic subtypes of FTD are currently lacking.
Kevin Menden, Margherita Francescatto, Tenzin Nyima, Cornelis Blauwendraat, Ashutosh Dhingra, Melissa Castillo-Lizardo, Noémia Fernandes, Lalit Kaurani, Deborah Kronenberg-Versteeg, Burcu Atasu, Eldem Sadikoglou, Barbara Borroni, Salvador Rodriguez-Nieto, Javier Simon-Sanchez, Andre Fischer, David Wesley Craig, Manuela Neumann, Stefan Bonn, Patrizia Rizzu, Peter Heutink   +19 more
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Prosopagnosia, Other Specific Cognitive Deficits, and Behavioral Symptoms: Comparison between Right Temporal and Behavioral Variant of Frontotemporal Dementia

Vision, 2022
Right temporal variant of frontotemporal dementia (rtv-FTD) represents an uncommon and recently described frontotemporal dementia (FTD) entity presenting with symptoms in many ways comparable to those of the frontal or behavioral variant of FTD (bv-FTD).
Christos Koros, Ion Beratis, Stavroula Matsi, Anastasia Bougea, Anastasios Bonakis, Ioannis Papatriantafyllou, Efthalia Angelopoulou, Elisabeth Kapaki, Leonidas Stefanis, Sokratis G. Papageorgiou   +9 more
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Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort– comparison with sporadic primary progressive aphasia [PDF]

, 2023
Data availability: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.Supplementary material: available online at https://academic.oup.com/braincomms/article/5/2/fcad036/7044705 ...
Borroni, B, van Swieten, JC, Seelaar, H, Moreno, F, MacDougall, AM, Bocchetta, M, Convery, RS, Otto, M, Greaves, CV, Hardy, C, Tartaglia, MC, Ducharme, S, Graff, C, Sanchez-Valle, R, Samra, K, Laforce, R, Jiskoot, LC, Rohrer, JD, Cash, DM, Santana, I, Butler, CR, Gerhard, A, Russell, LL, Galimberti, D, Warren, JD, Vandenberghe, R, Finger, E, Levin, J, de Mendonça, A, Sorbi, S, Masellis, M, Bouzigues, A, Synofzik, M, Pasquier, F, Rowe, JB, Le Ber, I   +35 more
core   +1 more source