Results 31 to 40 of about 30,886 (249)

Cerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]

, 2010
Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...
Bibl, Mirko, Esselmann, Hermann, Kornhuber, Johannes, Lewczuk, Piotr, Mollenhauer, Brit, Otto, Markus, Rüther, Eckart, Wiltfang, Jens, Wolf, Stefanie   +8 more
core   +1 more source

Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar degeneration

Journal of Neurology Neurosurgery & Psychiatry, 2020
Objective To assess the diagnostic and prognostic value of serum neurofilament light (NfL) and serum phospho-Tau181 (p-Tau181) in a large cohort of patients with frontotemporal lobar degeneration (FTLD).
A. Benussi, T. Karikari, N. Ashton, S. Gazzina, E. Premi, L. Benussi, R. Ghidoni, Juan Lantero Rodriguez, A. Emeršič, Joel Simrén, G. Binetti, Silvia Fostinelli, Marcello Giunta, R. Gasparotti, H. Zetterberg, K. Blennow, B. Borroni   +16 more
semanticscholar   +1 more source

Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football [PDF]

, 2017
IMPORTANCE: Players of American football may be at increased risk of long-term neurological conditions, particularly chronic traumatic encephalopathy (CTE).
Abdolmohammadi, Bobak, Alosco, Michael L., Alvarez, Victor E., Baugh, Christine M., Cantu, Robert C., Chaisson, Christine E., Cormier, Kerry A., Daneshvar, Daniel H., Goldstein, Lee E., Huber, Bertrand R., Katz, Douglas I., Kiernan, Patrick T., Kowall, Neil W., Kubilus, Caroline A., Martin, Brett M., McClean, Michael D., McHale, Lisa, McKee, Ann C., Mez, Jesse, Montenigro, Phillip H., Murphy, Lauren, Nowinski, Christopher J., Solomon, Todd M., Stein, Thor D., Stern, Robert A., Tripodis, Yorghos, Weuve, Jennifer   +26 more
core   +1 more source

Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease

Neurology, 2020
Objective To test the hypothesis that plasma total tau (t-tau) and neurofilament light chain (NfL) concentrations may have a differential role in the study of frontotemporal lobar degeneration syndromes (FTLD-S) and clinically diagnosed Alzheimer disease
I. Illán-Gala, A. Lleó, A. Karydas, A. Staffaroni, H. Zetterberg, Rajeev Sivasankaran, L. Grinberg, S. Spina, J. Kramer, E. Ramos, G. Coppola, R. La Joie, G. Rabinovici, D. Perry, M. Gorno‐Tempini, W. Seeley, B. Miller, H. Rosen, K. Blennow, A. Boxer, J. Rojas   +20 more
semanticscholar   +1 more source

Brain MR Spectroscopy Changes Precede Frontotemporal Lobar Degeneration Phenoconversion in Mapt Mutation Carriers. [PDF]

, 2019
Background and purposeThe objective of this study was to longitudinally investigate the trajectory of change in 1 H MRS measurements in asymptomatic MAPT mutation carriers who became symptomatic during follow-up, and to determine the time at which the ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill, Gunter, Jeffrey L, Haley, Dana, Jones, David, Kantarci, Kejal, Knopman, David, Kraft, Ruth, Lapid, Maria, Lesnick, Timothy, Rademakers, Rosa, Rosen, Howie, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +22 more
core   +3 more sources

Serum Glial Fibrillary Acidic Protein (GFAP) Is a Marker of Disease Severity in Frontotemporal Lobar Degeneration

Journal of Alzheimer's Disease, 2020
Background: It is still unknown if serum glial fibrillary acidic protein (GFAP) is a useful marker in frontotemporal lobar degeneration (FTLD). Objective: To assess the diagnostic and prognostic value of serum GFAP in a large cohort of patients with FTLD.
A. Benussi, N. Ashton, T. Karikari, S. Gazzina, E. Premi, L. Benussi, R. Ghidoni, Juan Lantero Rodriguez, A. Emeršič, G. Binetti, Silvia Fostinelli, Marcello Giunta, R. Gasparotti, H. Zetterberg, K. Blennow, B. Borroni   +15 more
semanticscholar   +1 more source

Delusions in frontotemporal lobar degeneration [PDF]

, 2009
We assessed the significance and nature of delusions in frontotemporal lobar degeneration (FTLD), an important cause of young-onset dementia with prominent neuropsychiatric features that remain incompletely characterised.
Alladi, Arciniegas, Bak, Ballard, Cairns, Catherine J. Mummery, Chan, Clement T. Loy, Elizabeth L. Sampson, Engelborghs, Geroldi, Gregory, Gregory, Hirono, Hodges, Howard, Jason D. Warren, Levy, Martin N. Rossor, McKhann, Mendez, Mendez, Neary, Nick C. Fox, Nitrini, Ogar, Rascovsky, Rohani Omar, Rosen, Scarmeas, Swartz, Tartaglia, Waddington   +32 more
core   +2 more sources

Genetics of Frontotemporal Lobar Degeneration

Frontiers in Neurology, 2012
Frontotemporal Lobar Degeneration (FTLD) is the most frequent neurodegenerative disorder with a presenile onset. It presents with a spectrum of clinical manifestations, ranging from behavioural and executive impairment to language disorders and motor ...
Daniela eGalimberti, Elio eScarpini
doaj   +1 more source

Validation of the German Revised Addenbrooke's Cognitive Examination for Detecting Mild Cognitive Impairment, Mild Dementia in Alzheimer's Disease and Frontotemporal Lobar Degeneration [PDF]

, 2010
Background/Aims: The diagnostic accuracy of the German version of the revised Addenbrooke's Cognitive Examination (ACE-R) in identifying mild cognitive impairment (MCI), mild dementia in Alzheimer's disease (AD) and mild dementia in frontotemporal lobar ...
Aguilar, C. A., Alexopoulos, P., Danek, Adrian, Diehl-Schmid, J., Ebert, A., Foerstl, H., Gourzis, P., Kneib, T., Kornhuber, J., Kurz, A., Natale, B., Perneczky, R., Richter-Schmidinger, T., Schoell, E., Weih, M.   +14 more
core   +1 more source

Apraxia profiles—A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Apraxia is common in neurodegenerative dementias but underrepresented in clinical workup for differential diagnoses. Methods Praxis‐profiles were assessed with the Dementia Apraxia Test in 93 patients with early stages of biologically ...
Andreas Johnen, Sophia Reul, Heinz Wiendl, Sven G. Meuth, Thomas Duning   +4 more
doaj   +1 more source