Results 21 to 30 of about 14,742 (206)

Imaging Frontotemporal Lobar Degeneration

Current Neurology and Neuroscience Reports, 2014
The term frontotemporal lobar degeneration (FTLD) refers to a group of neurodegenerative disorders that target the frontal and temporal lobes. It accounts for approximately 10 % of pathologically confirmed dementias but has been demonstrated to be as prevalent as Alzheimer's disease in patients below the age of 65.
Janine, Diehl-Schmid, Oezguer A, Onur, Jens, Kuhn, Traugott, Gruppe, Alexander, Drzezga   +4 more
openaire   +3 more sources

Underdiagnosis of frontotemporal lobar degeneration in Brazil [PDF]

Dementia & Neuropsychologia, 2007
Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that involves the frontal and anterior temporal lobes. It is characterized by prominent behavioral and language disorders.
Valéria Santoro Bahia
doaj   +4 more sources

Neuroanatomical normative modelling in frontotemporal lobar degeneration: higher heterogeneity in the behavioural variant. [PDF]

J Neurol
Data availability: Data used in preparation of this article were obtained from the Frontotemporal Lobar Degeneration Neuroimaging Initiative (FTLDNI) and the 4-Repeat Tauopathy Neuroimaging Initiative (4RTNI) databases (https://4rtni-ftldni.ini.usc.edu/
Konwar S, Hunyadvari N, Venneri A, Cole JH, Bocchetta M, Frontotemporal Lobar Degeneration Neuroimaging Initiative and for the 4-Repeat Tauopathy Neuroimaging Initiative.   +5 more
europepmc   +2 more sources

Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes [PDF]

, 2022
Researchers typically study physiological responses either after stimulus onset or when the emotional valence of an upcoming stimulus is revealed. Yet, participants may also respond when they are told that an emotional stimulus is about to be presented ...
Lwi, Sandy J, Haase, Claudia M, Chen, Kuan-Hua, Rankin, Katherine P, Toller, Gianina, Rosen, Howard J, Otero, Marcela C, Hua, Alice Y, Miller, Bruce L, Levenson, Robert W   +9 more
core   +1 more source

A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration. [PDF]

PLoS ONE, 2013
The transactive response DNA-binding protein (TDP-43) is a major component of the abnormal intracellular inclusions that occur in two common neurodegenerative diseases of humans: (1) a subtype of frontotemporal lobar degeneration and (2) amyotrophic ...
Patrick J Bosque, Philip J Boyer, Priya Mishra   +2 more
doaj   +1 more source

Unpicking frontotemporal lobar degeneration [PDF]

Brain, 2011
Not so long ago, frontotemporal lobar degeneration (FTLD) seemed quite simple. Apart from rare variants of Alzheimer's disease and the occasional obscure neurodegenerative disease that could not be classified, FTLD was synonymous with Pick's disease, first described by Arnold Pick (1892) in a series of patients with ‘circumscribed atrophy’ and aphasia.
Love, Seth, Spillantini, Maria Grazia
openaire   +3 more sources

Patterns of Microglial Cell Activation in Frontotemporal Lobar Degeneration [PDF]

, 2013
AIMS: Pathological heterogeneity within patients with Frontotemporal lobar degeneration (FTLD) in general precludes the accurate assignment of diagnostic subtype in life.
Pickering-Brown, Stuart, Snowden, Julie S, Robinson, Andrew C, Thompson, Jennifer C, Rollinson, Sara, Mann, David MA, Gerhard, Alexander, Mann, David M A, Davidson, Yvonne S, Robinson, Andrew C; id_orcid, Lant, Suzannah B   +10 more
core   +1 more source

New Perspective on Parkinsonism in Frontotemporal Lobar Degeneration [PDF]

Journal of Movement Disorders, 2013
Frontotemporal dementia (FTD) is the second most common type of presenile dementia. Three clinical prototypes have been defined; behavioral variant FTD, semantic dementia, and progressive nonfluent aphasia.
Hee Kyung Park, Sun J. Chung
doaj   +1 more source

Frontotemporal Lobar Degeneration [PDF]

Neurologic Clinics, 2007
Frontotemporal lobar degeneration (FTLD) is a syndromic diagnosis that encompasses at least three different variants. Imaging modalities are clinically useful in FTLD, although pathology remains the gold standard for definitive diagnosis. To date, four different genes have been identified that account for FTLD.
openaire   +2 more sources

Frontotemporal Lobar Degeneration Without Lobar Atrophy [PDF]

Archives of Neurology, 2006
Frontotemporal lobar degeneration with ubiquitin-only-immunoreactive neuronal inclusions (FTLD-U) is the most common form of frontotemporal dementia. Neuronal loss and gliosis in cornu ammonis 1 and the subiculum of the hippocampus are features of hippocampal sclerosis (HpScl), which occurs in many cases of FTLD-U.To determine if there were any ...
Keith A, Josephs, Jennifer L, Whitwell, Clifford R, Jack, Joseph E, Parisi, Dennis W, Dickson   +4 more
openaire   +2 more sources