Results 11 to 20 of about 14,742 (206)
Genetics of Frontotemporal Lobar Degeneration [PDF]
Frontiers in Neurology, 2012 Frontotemporal Lobar Degeneration (FTLD) is the most frequent neurodegenerative disorder with a presenile onset. It presents with a spectrum of clinical manifestations, ranging from behavioural and executive impairment to language disorders and motor ...
Daniela eGalimberti, Elio eScarpini
doaj +6 more sources
Frontotemporal lobar degeneration
Nature Reviews Disease Primers, 2023 Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset dementia and presents with early social-emotional-behavioural and/or language changes that can be accompanied by a pyramidal or extrapyramidal motor disorder. About 20-25% of individuals with FTLD are estimated to carry a mutation associated with a specific FTLD ...
Murray Grossman +11 more
core +10 more sources
Neuropathology of frontotemporal lobar degeneration: A review [PDF]
Dementia & Neuropsychologia, 2013 Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. Three main clinical variants are widely recognized within the FTLD spectrum: the behavioural variant of frontotemporal dementia (bvFTD), semantic dementia (SD)
Valéria Santoro Bahia +2 more
doaj +5 more sources
Delusions in frontotemporal lobar degeneration [PDF]
Journal of Neurology, 2009 We assessed the significance and nature of delusions in frontotemporal lobar degeneration (FTLD), an important cause of young-onset dementia with prominent neuropsychiatric features that remain incompletely characterised. The case notes of all patients meeting diagnostic criteria for FTLD attending a tertiary level cognitive disorders clinic over a ...
Omar, R. +6 more
openaire +6 more sources
Frontotemporal Lobar Degeneration and microRNAs [PDF]
Frontiers in Aging Neuroscience, 2016 Frontotemporal lobar degeneration (FTLD) includes a spectrum of disorders characterized by changes of personality and social behaviour and, often, a gradual and progressive language dysfunction.
Paola ePiscopo +4 more
doaj +3 more sources
The genetics of frontotemporal lobar degeneration
Current Opinion in Neurology, 2007 This review addresses the latest developments in the genetics of frontotemporal lobar degeneration. 'Frontotemporal lobar degeneration' is the clinical term used to describe a heterogeneous neurodegenerative syndrome that includes frontotemporal dementia, semantic dementia, progressive nonfluent aphasia and progressive apraxia.
Pickering-Brown, Stuart +3 more
core +5 more sources
Brazilian Journal of Psychiatry, 2011 OBJECTIVE: To identify the therapeutic options available for treatment of cognitive and behavioral symptoms in frontotemporal lobar degeneration. METHOD: Systematic review using the descriptors "frontotemporal lobar degeneration" OR "frontotemporal ...
Maria da Glória Portugal +2 more
doaj +2 more sources
Genetics of frontotemporal lobar degeneration
Annals of Indian Academy of Neurology, 2010 Frontotemporal lobar degeneration (FTLD) is a highly heterogenous group of progressive neurodegenerative disorders characterized by atrophy of prefrontal and anterior temporal cortices.
Aswathy P, Jairani P, Mathuranath P
doaj +3 more sources
Progranulin and frontotemporal lobar degeneration
Acta Neuropathologica, 2007 Frontotemporal lobar degeneration is the term used to describe the non-Alzheimer clinical syndromes of frontotemporal dementia, semantic dementia and progressive non-fluent aphasia, regardless of the underlying neuropathological features. Considerable progress has been made in recent years in our understanding of the aetiology of this disorder, notably
Pickering-Brown, Stuart M.
openaire +3 more sources
Progranulin in frontotemporal lobar degeneration and neuroinflammation [PDF]
Journal of Neuroinflammation, 2007 Progranulin (PGRN) is a pleiotropic protein that has gained the attention of the neuroscience community with recent discoveries of mutations in the gene for PGRN that cause frontotemporal lobar degeneration (FTLD).
Hutton Michael L +3 more
doaj +3 more sources