Results 31 to 40 of about 14,742 (206)

Response to: Clinical Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP‐43 A and B [PDF]

open access: yesAnnals of Clinical and Translational Neurology
Sergi Borrego‐Écija   +3 more
doaj   +2 more sources

Cerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]

open access: yes, 2010
Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...
Hermann Esselmann   +17 more
core   +1 more source

The structural neuroanatomy of music emotion recognition: evidence from frontotemporal lobar degeneration. [PDF]

open access: yes, 2011
Despite growing clinical and neurobiological interest in the brain mechanisms that process emotion in music, these mechanisms remain incompletely understood.
Omar, Rohani   +45 more
core   +1 more source

Dementias show differential physiological responses to salient sounds. [PDF]

open access: yes, 2015
Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals,
Nicholas, Jennifer M   +43 more
core   +1 more source

Combined evaluation of FDG-PET and MRI improves detection and differentiation of dementia. [PDF]

open access: yes, 2011
INTRODUCTION: Various biomarkers have been reported in recent literature regarding imaging abnormalities in different types of dementia. These biomarkers have helped to significantly improve early detection and also differentiation of various dementia ...
Möller, Harald E   +25 more
core   +1 more source

The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons [PDF]

open access: yes, 2013
Frontotemporal lobar degeneration (FTLD) is the one of the most frequent neurodegenerative disorders characterized by behavioral and executive impairment, language disorders and motor dysfunction.
Holton, Janice L.   +27 more
core   +1 more source

Apraxia profiles—A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Apraxia is common in neurodegenerative dementias but underrepresented in clinical workup for differential diagnoses. Methods Praxis‐profiles were assessed with the Dementia Apraxia Test in 93 patients with early stages of biologically ...
Andreas Johnen   +4 more
doaj   +1 more source

Voice processing in dementia: a neuropsychological and neuroanatomical analysis. [PDF]

open access: yes, 2011
Voice processing in neurodegenerative disease is poorly understood. Here we undertook a systematic investigation of voice processing in a cohort of patients with clinical diagnoses representing two canonical dementia syndromes: temporal variant ...
Julia C. Hailstone   +13 more
core   +1 more source

A Genome-Wide Screening and SNPs-to-Genes Approach to Identify Novel Genetic Risk Factors Associated with Frontotemporal Dementia [PDF]

open access: yes, 2015
Frontotemporal dementia (FTD) is the second most prevalent form of early onset dementia after Alzheimer’s disease (AD). We performed a case-control association study in an Italian FTD cohort (n = 530) followed by the novel SNPs-to-genes approach and ...
Maletta, Raffaele G   +121 more
core   +1 more source

Human Ubiquilin 2 and TDP-43 copathology drives neurodegeneration in transgenic Caenorhabditis elegans

open access: yesG3: Genes, Genomes, Genetics, 2021
Amyotrophic lateral sclerosis (ALS) is a debilitating, fatal neurodegenerative disease that causes rapid muscle wasting. It shares a spectrum of symptoms and pathology with frontotemporal lobar degeneration (FTLD).
Aleen D Saxton, Brian C Kraemer
doaj   +1 more source

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