Results 81 to 90 of about 24,976 (233)
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning +3 more
wiley +1 more source
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu +27 more
wiley +1 more source
Apraxia in progressive nonfluent aphasia [PDF]
The clinical and neuroanatomical correlates of specific apraxias in neurodegenerative disease are not well understood. Here we addressed this issue in progressive nonfluent aphasia (PNFA), a canonical subtype of frontotemporal lobar degeneration that has
Rohrer, J.D., Rossor, M.N., Warren, J.D.
core
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins [PDF]
An expanded GGGGCC repeat in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. A fundamental question is whether toxicity is driven by the repeat RNA itself and/or by dipeptide repeat proteins ...
Cabecinha, M +19 more
core +1 more source
Abstract This study investigated Theory of Mind (ToM) deficits in patients with suspected idiopathic normal pressure hydrocephalus (iNPH), a condition affecting motor, cognitive and autonomic functions. Given the overlap between ToM‐related neural networks and those affected in iNPH, we examined whether ToM impairments are a feature of the disease ...
Akrivi Vatsi +9 more
wiley +1 more source
From mechanism to phenotype: What fits in a basket trial
Epilepsia, EarlyView.
Kette D. Valente
wiley +1 more source
Underdiagnosis of frontotemporal lobar degeneration in Brazil
Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that involves the frontal and anterior temporal lobes. It is characterized by prominent behavioral and language disorders.
Valéria Santoro Bahia
doaj +1 more source
Distribution of TDP-43 Pathology in Hippocampal Synaptic Relays Suggests Transsynaptic Propagation in Frontotemporal Lobar Degeneration [PDF]
Pouya Jamshidi +7 more
openalex +1 more source
Cost‐effectiveness and impact at scale of collaborative care and lecanemab for Alzheimer's disease
Abstract INTRODUCTION Advancements in disease‐modifying therapies and collaborative dementia care programs have created opportunities to transform care for people with Alzheimer's disease. METHODS We modeled people aged 71 across three scenarios: 18 months of lecanemab, collaborative care, and combined interventions.
Kelly J. Atkins +2 more
wiley +1 more source
Biomarkers in frontotemporal lobar degeneration [PDF]
Recent findings assessing the utility of neuroimaging and biofluid biomarkers are reviewed that help identify patients with frontotemporal lobar degeneration (FTLD) spectrum abnormality.Neuroimaging studies using T1 structural MRI and diffusion tensor imaging (DTI) distinguish between patients with FTLD and Alzheimer's disease, although the reliability
openaire +2 more sources

