Results 91 to 100 of about 61,998 (261)

A protracted, postherpetic neuralgic ulcer treated with risperidone and intranasal butorphanol

open access: yesJAAD Case Reports, 2021
Giuseppe Ingrasci, BS   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Frost Depth Penetration and Frost Heave in Frost Susceptible Soils [PDF]

open access: yesAirfield and Highway Pavements 2019, 2019
W. A. Lein   +3 more
openaire   +2 more sources

High sensitivity of herbaceous legumes to freezing: Insights from a multiyear snow removal study

open access: yesEcosphere
Reductions in snow cover resulting from winter climate change are anticipated to increase the intensity of freezing exposure for overwintering herbaceous plants in many northern temperate regions.
Samuel L. Rycroft, Hugh A. L. Henry
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Uremic Frost [PDF]

open access: yesMayo Clinic Proceedings, 2008
Nimesh, Bhattarai, Mukta, Panda
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Delusional infestation complicated by gangrene and osteomyelitis requiring finger amputation

open access: yesJAAD Case Reports, 2021
Julio A. Diaz-Perez, MD   +5 more
doaj   +1 more source

Experimental Investigation on Frost Formation on Cold Surface under Natural Convection Conditions

open access: yesZhileng xuebao, 2019
A microscopic visualization method was applied experimentally, where comparative observations of frosting processes were conductedunder the same conditionson bare aluminum and hydrophobic surface with contact angles of 78° and 141°, respectively.
Zhou Shengqi   +3 more
doaj  

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