Results 71 to 80 of about 128,601 (309)
Hidradenitis Suppurativa Tunnels: Unveiling a Unique Disease Entity
JID InnovationsHidradenitis suppurativa tunnel structures lined with epithelium within the dermis are unique features of advanced disease stages that significantly impair patients’ QOL.
Nicole Vecin +8 more
doaj +1 more source
The Baltic Journal of Road and Bridge Engineering, 2015 Seeking to reduce a negative impact of unfavourable weather conditions on road traffic, many countries introduce modern technologies allowing to objectively assessing meteorological conditions of roads.
Lina Juknevičiūtė-Žilinskienė +1 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 1976 not peer reviewedSubmitted by Conor Tinch (ctinc2@uis.edu) on 2014-04-08T22:15:15Z No. of bitstreams: 3 f929-frost-02.mp3: 22299115 bytes, checksum: 5ebe8080e8d1024e44bd5e5975376f6b (MD5) f929-frost-03.mp3: 20807628 bytes, checksum ...
Frost, James
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 1910 American poet Robert Frost (1874-1963) was born in San Francisco, California. After the death of his father, the family moved to New England, which provided the backdrop for Frost's trademark regional poetry. Frost briefly attended both Dartmouth College
Frost, Robert
core
Use of Midodrine for Intraoperative Hemostasis in Cutaneous and Percutaneous Surgery
JID InnovationsOwing to the increasingly high volume of cutaneous and percutaneous procedures performed annually, the demand for local anesthesia has steadily risen. The gold-standard formulations for local anesthesia contain epinephrine at a concentration of 1:100,000
Joanna Dong +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source