Results 101 to 110 of about 12,356 (220)
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Developments in embryo freezing techniques in recent years have increased the chance of pregnancy after frozen embryo transfers. In this study we aimed to compare the pregnancy outcomes between fresh (ET) and frozen-thawed embryo transfer (FET) and to ...
Goker, Ege Nazan Tavmergen +10 more
core +1 more source
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz +6 more
wiley +1 more source
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos +3 more
wiley +1 more source
Frozen embryo transfer prevents the detrimental effect of high estrogen on endometrium receptivity [PDF]
WOS: 000398542000008PubMed ID: 28506949Objective: To investigate whether serum levels of estradiol affect reproductive outcomes of normoresponder women undergoing fresh embryo transfer (ET) versus frozen-thawed ET (FET). Material and Methods: Two hundred
Dokuzeylül Güngör, Nur +8 more
core +1 more source
ABSTRACT Metal contamination in aquatic ecosystems poses substantial risks to freshwater organisms, with mixture effects often deviating from predictions based on single‐metal toxicity. Understanding how age‐specific sensitivities and multiple exposure pathways influence mixture effects is critical for accurate risk assessment.
Sanah Majid +3 more
wiley +1 more source
The association between pregnancy outcomes and frozen-thawed embryo transfer cycles based on D3 cell count in high-quality blastocysts [PDF]
ObjectiveTo investigate the number of cells in D3-stage embryos of high-quality blastocysts as a contributing factor, to evaluate the clinical pregnancy outcomes in frozen-thawed embryo transfer cycles, and to determine the impact of D3-stage cell count ...
Youman Zeng +5 more
core +1 more source
Female obesity does not impact live birth rate after frozen-thawed blastocyst transfer
International audienceSTUDY QUESTION Does female obesity affect live birth rate after frozen-thawed blastocyst transfer? SUMMARY ANSWER Live birth rate was not statistically different between obese and normal weight patients after frozen-thawed ...
Caillet, P +6 more
core +1 more source
Abstract Background Laparoscopic intrauterine artificial insemination (Lap‐AI) is used in sheep genetic improvement programmes. However, the lambing rate (LR) (i.e., the proportion of inseminated ewes that lamb) following Lap‐AI is variable. Previously, one small UK study investigated factors associated with LR, but it did not adjust for dependencies ...
Mike J. Glover +2 more
wiley +1 more source
Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika +6 more
wiley +1 more source

