Results 61 to 70 of about 12,356 (220)

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Fresh or frozen day 6 blastocyst transfer: is there still a question?

Reproductive Biology and Endocrinology
Background The Live Birth Rate (LBR) after day 5 (D5) blastocyst transfer is significantly higher than that with D6 embryos in both fresh and frozen-vitrified embryo transfer cycles, according to the most recently published meta-analyses.
Lucile Ferreux, Mathilde Bourdon, Ahmed Chargui, Julie Firmin, Chloé Maignien, Pietro Santulli, Catherine Patrat, Khaled Pocate-Cheriet   +7 more
doaj   +1 more source

Effect of maternal age, embryo number and quality on pregnancy outcome during frozen embryo transfer cycle

Frontiers in Endocrinology
BackgroundTo investigate the effects of maternal age, the number of transferred embryos, and embryo quality on pregnancy-related outcomes in frozen-thawed embryo transfer cycles.DesignA retrospective cohort study was conducted on 1031 frozen-thawed ...
Wenyi Gao, Weiwei Tang, Caixia Li, Yun Deng, Yao Chen, Yanru Zhang, Xiaohong Pan, Chunyan Yang, Yuanyuan Liu, Fang Xiong, Xin Jin   +10 more
doaj   +1 more source

Methods for endometrial preparation in frozen-thawed embryo transfer cycles

, 2016
Frozen-thawed (FT) embryo transfer is a procedure used for the storage and transfer of excess embryos obtained during in vitro fertilization-intracytoplasmic sperm injection cycles.
Kalem, Muberra Namli, Gurgan, Timur, Kalem, Ziya   +2 more
core   +1 more source

Live birth after frozen-thawed embryo transfer: which endometrial preparation protocol is better?

, 2020
Objective: To compare the clinical outcomes of modified natural cycle (mNC) and artificial cycle (AC) protocols for frozen embryo transfers. Material and methods: A total of 490 frozen-thawed autologous embryo transfer cycles, performed in a single ...
Goker, Ege Nazan Tavmergen, Calimlioglu, Nilufer, Meseri, Reci, Tavmergen, Erol, Acet, Ferruh, Sahin, Gulnaz   +5 more
core   +1 more source

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing

Journal of Translational Medicine, 2022
Background This study aimed to analyze the clinical outcomes of blastocyst which undergo the preimplantation genetic testing (PGT) transplantation from frozen-thawed D5 and D6. In addition, the effect of blastocyst grade on clinical and neonatal outcomes
Guanling Yu, Shuiying Ma, Hui Liu, Yujin Liu, Haozhen Zhang, Wenjia Zhang, Keliang Wu   +6 more
doaj   +1 more source

Perinatal outcomes of children born after frozen-thawed embryo transfer: a Nordic cohort study from the CoNARTaS group

, 2013
What are the risks of adverse outcomes in singletons born after frozen-thawed embryo transfer (FET)
Nygren, Karl Gosta, Forman, Julie, Romundstad, Liv Bente, Romundstad, LB, Wennerholm, Ulla-Britt,, Bergh, Christina, Forman, J, Wennerholm, UB, Gissler, M, Henningsen, Anna-Karina Aaris, Pinborg, Anja, Wennerholm, Ulla-Britt, Tiitinen, A, Bergh, C, Skjaerven, Rolv, Skjaerven, R, Gissler, Mika, Tiitinen, Aila, Nygren, KG, Bergh, Christina,, Pinborg, A   +20 more
core   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

High‐Dose Hormone Replacement Therapy Improved Embryo Transfer Outcomes in a Woman With 21‐Hydroxylase Deficiency Who Had Persistently High Serum Progesterone Levels: A Case Report and Literature Review

Clinical Case Reports
Women with 21‐hydroxylase deficiency have reduced fertility because of excessive production of adrenal androgen and progesterone, which can inhibit folliculogenesis, disturb the normal gonadotropin secretion pattern and development of the endometrium ...
Yuri Mizusawa, Hiroaki Shibahara, Masahide Shiotani   +2 more
doaj   +1 more source