Results 31 to 40 of about 76,844 (237)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Influence of Biologically Inert Protective Coating Based on Pectin Substances on PUFA Quality and Shelf-Life of Frozen Fish

Holodilʹnaâ Tehnika i Tehnologiâ, 2018
The influence of a biologically inert protective coating on the basis of low-esterified pectin substances (LEPS) on the qualitative indicators of frozen fish and its lipids is studied in this paper: organoleptic, physico-chemical, structural-mechanical ...
A. Gerasim, S. Patyukov, N. Patyukova
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Veterinary and sanitary evaluation of frozen fish imported into Ukraine for presence of antibacterial substances residues

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2018
Significant and unlimited use of antibacterial drugs, leads to their accumulation in the aquatic environment, tissues of fish, and, accordingly, in fish products.
Z. V. Malimon, М. D. Kukhtyn, N. E. Grynevych, I. M. Azyrkina   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Establishing the safety and quality of fish and fish products using unique methods

Ukrainian Journal of Veterinary and Agricultural Sciences
Food business operators involved in the farming, storage, and sale of fish and the production of fish products must implement traceability systems and food safety assurance systems to enable risk-based control throughout the entire production cycle ...
N. M. Bohatko, L. G. Bartkiv, N. V. Tyshkivska, T. G. Mazur, А. F. Bohatkо   +4 more
doaj   +1 more source

Pathway-oriented action of dietary essential oils to prevent muscle protein oxidation and texture deterioration of farmed rainbow trout

Animal, 2019
Recently, great attention has been directed towards the use of essential oils from aromatic plants as antimicrobials and antioxidant in food matrix. Fish is well known to be a high perishable food. Indeed, fish muscle is susceptible to suffer protein and
H.M.C. Santos, L. Méndez, G. Secci, G. Parisi, R. Martelli, I. Medina   +5 more
doaj   +1 more source

Fish for sustainable quality monitoring product safety

Vestnik MGTU, 2023
To provide consumers with high-quality and safe products, to prevent the entry of low-quality and dangerous food products into the consumer market, monitoring programs are provided. The results of monitoring samples of frozen fish of various families and
Reznichenko I. Yu., Egushova E. A., Donchenko T. А.   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source