Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice [PDF]
Oxidative stress, a central mediator of cardiovascular disease, results in loss of the prosthetic haem group of soluble guanylate cyclase (sGC), preventing its activation by nitric oxide (NO). Here we introduce Apo-sGC mice expressing haem-free sGC.
Bloch, Kenneth D +17 more
core +1 more source
Effect of diet on postprandial glycemic and insulin responses in healthy dogs
IntroductionDog owners have gradually changed their approach, paying more attention to the nutrition and health of their animals. Various pet foods with different ingredients and nutritional characteristics are available on the market.
Alessandro Vastolo +6 more
doaj +1 more source
Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder) +2 more
core +1 more source
Effect of thiols on fructosamine assay [PDF]
AbstractFresh human serum, gGAPDH and β‐mercaptoethanol were used to examine the effect of thiols on fructosamine assay. The kinetics of the reaction with both fresh human serum and gGAPDH displayed biphasic behaviour (fast and slow). When the thiols were modified with IAA, the kinetics only demonstrated the slow phase. Since the absorbance increase in
W, Liu, R, He
openaire +2 more sources
Serum N-Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism [PDF]
BACKGROUND: N‐terminal type III procollagen propeptide (PIIINP) is a biomarker of soft tissue proliferation. Hypersomatotropism (HS) is associated with soft tissue proliferation.
Church, D B +4 more
core +3 more sources
Status of Serum Fructosamine in Diabetic Subjects in Udaipur, Rajasthan [PDF]
Background: Estimation of glycated haemoglobin and fructosamine in diabetic patient for the assessment of glycemic control isgaining importance now a day. Little data is available about assessment of fructosamine in our area.
Avdhesh Kumar Sharma, Kishan Lal Mali
doaj
Fasting glucose (FG) and glycated hemoglobin A1c (HbA1c) perform sub-optimally in people of African origin, especially in individuals with sickle-cell trait (SCT).
Sarah Skinner +14 more
doaj +1 more source
Protein–phenolic interactions and inhibition of glycation – combining a systematic review and experimental models for enhanced physiological relevance [PDF]
Background: While antiglycative capacity has been attributed to (poly)phenols, the exact mechanism of action remains unclear. Studies so far are often relying on supra-physiological concentrations and use of non-bioavailable compounds.<p></p>
Combet, E. +2 more
core +1 more source
Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F +6 more
core +3 more sources
Ultrafast python‐integrated single‐entity electrochemical sensor for detecting glycated albumin
Traditional biosensors suffer from the fact that recognition receptors are immobilised and that they denature on electrodes. Instead here we use receptors freely in solution, minimising surface compression and preserving activity to boost signal efficiency. Python‐driven processing turns the electrochemical response into a rapid, robust readout.
Zihni Onur Uygun
wiley +1 more source

