Results 91 to 100 of about 21,838 (240)

CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4‐Fatty Acid β‐Oxidation Pathway

open access: yesAdvanced Science, 2022
Metabolic reprogramming is often observed in carcinogenesis, but little is known about the aberrant metabolic genes involved in the tumorigenicity and maintenance of stemness in cancer cells. Sixty‐seven oncogenic metabolism‐related genes in liver cancer
Hongquan Li   +10 more
doaj   +1 more source

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng   +14 more
wiley   +1 more source

Improved accuracy of cell surface shaving proteomics in Staphylococcus aureus using a false-positive control [PDF]

open access: yes, 2010
Proteolytic treatment of intact bacterial cells is an ideal means for identifying surface-exposed peptide epitopes and has potential for the discovery of novel vaccine targets.
Cordwell, Stuart J   +2 more
core   +1 more source

The genes encoding fructose bisphosphate aldolase inTrypanosoma bruceiare interspersed with unrelated genes [PDF]

open access: yesNucleic Acids Research, 1990
The fructose bisphosphate aldolase genes of Trypanosoma brucei are interspersed with unrelated genes whose transcript levels show no developmental modulation. Transcription appears approximately constant across the entire locus, suggesting that aldolase mRNA abundance is regulated post-transcriptionally.
S, Vijayasarathy   +6 more
openaire   +2 more sources

Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species

open access: yes
Allergy, EarlyView.
Kelvin Fu‐Kiu Ao   +11 more
wiley   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways. [PDF]

open access: yesPLoS ONE, 2012
Proteins involved in mitochondrial metabolic pathways engage in functionally relevant multi-enzyme complexes. We previously described an interaction between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase (SCHAD) and glutamate dehydrogenase (GDH ...
Srinivas B Narayan   +7 more
doaj   +1 more source

Molecular mechanism of ethylene stimulation of latex yield in rubber tree (Hevea brasiliensis) revealed by de novo sequencing and transcriptome analysis [PDF]

open access: yes, 2016
Differential expression of unigenes involved in hormone signaling in E8 and E24 compared to C samples of Hevea brasiliensis. Ethylene signalling pathway: ETR1: ETHYLENE RESPONSE 1; CTR1: CONSTITUTIVE TRIPLE RESPONSE 1; EIN2: ETHYLENE INSENSITIVE 2; EIN3:
Jin-Ping Liu   +3 more
core   +9 more sources

Phosphate Resupply Differentially Impacts the Shoot and Root Proteomes of Arabidopsis thaliana Seedlings

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith   +5 more
wiley   +1 more source

Ko‐Assemblierungen regulieren die katalytische Aktivität von Peptidfibrillen

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Katalytische selbstassemblierende Peptide (kSAPs) bilden Fibrillen, die die Retro‐Aldol‐Reaktion von Methodol katalysieren. Die Ko‐Assemblierung mit inaktiven Peptiden reguliert die katalytische Aktivität, indem sie die Zugänglichkeit des Substrats und den Abstand zum nukleophilen Lysin verändert.
Albin Lahu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy