Results 111 to 120 of about 21,838 (240)

Responses of the marine diatom Thalassiosira pseudonana to changes in CO2 concentration: a proteomic approach [PDF]

open access: yes, 2017
The concentration of CO2 in many aquatic systems is variable, often lower than the KM of the primary carboxylating enzyme Rubisco, and in order to photosynthesize efficiently, many algae operate a facultative CO2 concentrating mechanism (CCM).
Clement, Romain   +9 more
core   +4 more sources

Gluconeogenic Mutations in Pseudomonas Aeruginosa: Genetic Linkage between Fructose-bisphosphate Aldolase and Phosphoglycerate Kinase

open access: yesMicrobiology, 1987
Mutants of mucoid Pseudomonas aeruginosa defective in fructose-bisphosphate aldolase (FBA), NADP-linked glyceraldehyde-3-phosphate dehydrogenase (GAP) or 3-phosphoglycerate kinase (PGK) were unable to grow on gluconeogenic precursors like glutamate, succinate or lactate.
P C, Banerjee, A, Darzins, P K, Maitra
openaire   +2 more sources

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang   +6 more
wiley   +1 more source

Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer's disease but without amyloid deposits on positron emission tomography: Results from Bio‐Hermes Study participants

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs   +11 more
wiley   +1 more source

NADH-Mediated Gene Expression in Streptococcus pneumoniae and Role of Rex as a Transcriptional Repressor of the Rex-Regulon [PDF]

open access: yes, 2018
Nicotinamide adenine dinucleotides (NAD(H)) play a vital role in various biological processes, including keeping the cellular redox balance. In this study, we investigate the regulatory responses of Streptococcus pneumoniae D39 to NADH and characterize ...
Afzal, Muhammad   +2 more
core   +2 more sources

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

open access: yesCarbon Energy, Volume 8, Issue 1, January 2026.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian   +3 more
wiley   +1 more source

Fructose-1,6-bisphosphate aldolase encoded by a core gene of Mycoplasma hyopneumoniae contributes to host cell adhesion

open access: yesVeterinary Research, 2018
Mycoplasma hyopneumoniae is an important respiratory pathogen that causes great economic losses to the pig industry worldwide. Although some putative virulence factors have been reported, pathogenesis remains poorly understood.
Yanfei Yu   +9 more
doaj   +1 more source

Chemical and enzymatic routes to dihydroxyacetone phosphate [PDF]

open access: yes, 2018
Stereoselective carbon-carbon bond formation with aldolases has become an indispensable tool in preparative synthetic chemistry. In particular, the dihydroxyacetone phosphate (DHAP)-dependent aldolases are attractive because four different types are ...
Panke, Sven   +2 more
core  

Straightforward chemo-enzymatic synthesis of new aminocyclitols, analogues of valiolamine and their evaluation as glycosidase inhibitors. [PDF]

open access: yes, 2006
An efficient fructose-1,6-bisphosphate aldolase mediated synthesis of new aminocyclitol analogues of valiolamine is described. The one-pot process where four stereocentres are created involves the formation of two carbon–carbon bonds. One is catalysed by
Ahbala, Mustapha   +3 more
core   +3 more sources

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani   +6 more
wiley   +1 more source

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