Results 161 to 170 of about 372,352 (396)

Acute fructose intake suppresses fasting-induced hepatic gluconeogenesis through the AKT-FoxO1 pathway

open access: yesBiochemistry and Biophysics Reports, 2019
Excessive intake of fructose increases lipogenesis in the liver, leading to hepatic lipid accumulation and development of fatty liver disease. Metabolic alterations in the liver due to fructose intake have been reported in many studies, but the effect of
Tomoki Sato   +5 more
doaj  

Development of a continuous intensified process for conversion of hemicellulose sugars into furans using an agitated cell reactor

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study addresses significant process challenges associated with the reactive nature of hemicellulose‐derived furan intermediates in aqueous mediums. A continuous agitated cell reactor was used to intensify the extractive reaction using methyl isobutyl ketone as an extractive phase to isolate in situ the furan products obtained by ...
Abdullahi Adamu   +2 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

Exploiting agricultural residues for sustainable bioconversion: production of cellulolytic and lignin‐degrading enzymes

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Agroindustrial activity generates substantial waste during harvesting and processing. This study investigated the potential use of sugarcane bagasse, corn cob husk, and wheat bran as substrates for enzyme production by Aspergillus niger and Ceriporiopsis subvermispora. Aspergillus niger and C. subvermispora exhibited comparable filter paperase
Arianne Tairyne de Souza   +4 more
wiley   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

Fructose shields human colorectal cancer cells from hypoxia-induced necroptosis

open access: yesnpj Science of Food
Recent studies have shown that high dietary fructose intake enhances intestinal tumor growth in mice. Our previous work indicated that glucose enables hypoxic colorectal cancer (CRC) cells to resist receptor-interacting protein (RIP)-dependent ...
Xiang-Han Huang, Ching-Ying Huang
doaj   +1 more source

FGF21-protection against fructose-induced lipid accretion and oxidative stress is influenced by maternal nutrition in male progeny

open access: yesJournal of Functional Foods, 2020
Fructose intake from added sugars correlates with the epidemic rise in metabolic syndrome. Nevertheless, consumption of beverages sweetened with fructose is allowed in gestation.
Elena Fauste   +9 more
doaj  

Biotechnological production of 2‐phenylethanol from agroindustrial byproducts: experimental evaluation, techno‐economic analysis, and life cycle assessment

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract 2‐Phenylethanol (2‐PE) is an alcohol with a rosy scent, commonly used as a fragrance, flavoring agent, and preservative in food and cosmetics. This study evaluates 2‐PE bioproduction using apple pomace and whey as low‐cost, biobased substrates for the growth of the yeast strain Kluyveromyces marxianus CBS600.
Fernanda Thimoteo Azevedo Jorge   +7 more
wiley   +1 more source

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