Results 71 to 80 of about 361,236 (411)
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Nature Network Boston, 2018 Metformin is a first-line drug for the treatment of individuals with type 2 diabetes, yet its precise mechanism of action remains unclear. Metformin exerts its antihyperglycemic action primarily through lowering hepatic glucose production (HGP).
R. Hunter +9 more
semanticscholar +1 more source
Modeling and Optimization of Lactic Acid Synthesis by the Alkaline Degradation of Fructose in a Batch Reactor [PDF]
, 2005 The present work deals with the determination of the optimal operating conditions of lactic acid synthesis by the alkaline degradation of fructose. It is a complex transformation for which detailed knowledge is not available.
Box G. E. P. +16 more
core +2 more sources
Absolute diffusion measurements of active enzyme solutions by NMR [PDF]
, 2018 The diffusion of enzymes is of fundamental importance for many biochemical processes. Enhanced or directed enzyme diffusion can alter the accessibility of substrates and the organization of enzymes within cells. Several studies based on fluorescence correlation spectroscopy (FCS) report enhanced diffusion of enzymes upon interaction with their ...
arxiv +1 more source
Dietary Fructose and the Metabolic Syndrome
Nutrients, 2019 Consumption of fructose, the sweetest of all naturally occurring carbohydrates, has increased dramatically in the last 40 years and is today commonly used commercially in soft drinks, juice, and baked goods.
M. Taskinen, C. Packard, J. Borén
semanticscholar +1 more source
Exercise performed immediately after fructose ingestion enhances fructose oxidation and suppresses fructose storage [PDF]
The American Journal of Clinical Nutrition, 2016 Exercise prevents the adverse effects of a high-fructose diet through mechanisms that remain unknown.We assessed the hypothesis that exercise prevents fructose-induced increases in very-low-density lipoprotein (VLDL) triglycerides by decreasing the fructose conversion into glucose and VLDL-triglyceride and fructose carbon storage into hepatic glycogen ...
Egli, Léonie +9 more
openaire +6 more sources
Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause [PDF]
, 2014 Background: Metabolic syndrome is characterized by the association of 3 or more risk factors, including: abdominal obesity associated with an excess of abdominal fat, insulin resistance, type 2 diabetes, dyslipidemia and hypertension.
Bernardes, Nathalia +8 more
core +2 more sources
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
ENZYME CONDUCTOMETRIC BIOSENSOR FOR FRUCTOSE DETERMINATION [PDF]
Biotechnologia Acta, 2013 The conductometric biosensor for fructose determination based on fructose dehydrogenase and potassium ferricyanide mediator as electron acceptor has been developed.
O. Y. Dudchenko +4 more
doaj +1 more source
Hepatology, 2019 Fructose intake is known to induce obesity, insulin resistance, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose drinking on gut leakiness, endotoxemia, and NAFLD and study the underlying ...
Young-Eun Cho +5 more
semanticscholar +1 more source
JCI Insight, 2020 Lung cancer (LC) is a leading cause of cancer-related deaths worldwide. Its rapid growth requires hyperactive catabolism of principal metabolic fuels. It is unclear whether fructose, an abundant sugar in current diets, is essential for LC.
Wen-Lian Chen +17 more
semanticscholar +1 more source