Results 91 to 100 of about 20,167 (239)
High fructose intake fails to induce symptomatic adaptation but may induce intestinal carriers
Gastroenterology Insights, 2010 Fructose has several interactions in man, including intolerance and promotion of some diseases. However, fructose in fruits and in prebiotics may be associated with benefits. Adaptation to regular fructose ingestion as defined for lactose could support a
Debra Heilpern +5 more
doaj +1 more source
DJ-1 as a deglycating enzyme: A unique function to explain a multifaceted protein? [PDF]
, 2017 The recently reported deglycating activity of DJ-1 reconciles several features previously described for the protein. The deglycating activity reported for DJ-1 may explain its different subcellular localizations, indeed the protein has been found in the ...
Bisaglia, Marco, DE LAZZARI, Federica
core +2 more sources
The FASEB Journal, Volume 39, Issue 20, 31 October 2025.The pro‐resolving lipid mediator PDX, and a novel synthetic analogue AN‐48, were orally administered (50 ng/g) daily to hamsters fed an obesity‐inducing diet. AN‐48 prevented hepatic triglyceride accretion and reduced the expression of fatty acid synthase (FASN), responsible for de novo lipogenesis.
Frédérik Desmarais +9 more
wiley +1 more source
N-glycosylation site occupancy in serum glycoproteins using multiple reaction monitoring liquid chromatography-mass spectrometry [PDF]
, 2007 Congenital disorders of glycosylation (CDGs) are a family of N-linked glycosylation defects associated with severe clinical manifestations. In CDG type-I, deficiency of lipid-linked oligosaccharide assembly leads to the underoccupancy of N-glycosylation ...
Hennet, T +2 more
core +1 more source
Advanced Science, Volume 12, Issue 37, October 6, 2025.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source
Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. [PDF]
, 2019 The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly ...
Bandyopadhyay, Guatam K +3 more
core
Sensitivity to wheat, gluten and FODMAPs in IBS: Facts or fiction? [PDF]
, 2015 IBS is one of the most common types of functional bowel disorder. Increasing attention has been paid to the causative role of food in IBS. Food ingestion precipitates or exacerbates symptoms, such as abdominal pain and bloating in patients with IBS ...
DE GIORGIO, Roberto +2 more
core +1 more source
Advanced Science, Volume 12, Issue 39, October 20, 2025.The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding +19 more
wiley +1 more source
Rhabdomyolysis: a genetic perspective [PDF]
, 2015 Rhabdomyolysis (RM) is a clinical emergency characterized by fulminant skeletal muscle damage and release of intracellular muscle components into the blood stream leading to myoglobinuria and, in severe cases, acute renal failure.
Alice R Gardiner +8 more
core +4 more sources
Simvastatin-induced cardiac autonomic control improvement in fructose-fed female rats
Clinics, 2011 OBJECTIVE: Because autonomic dysfunction has been found to lead to cardiometabolic disorders and because studies have reported that simvastatin treatment has neuroprotective effects, the objective of the present study was to investigate the effects of ...
Renata Juliana da Silva +5 more
doaj +1 more source