Results 41 to 50 of about 98,720 (282)

Sex and the single cell. II. There is a time and place for sex. [PDF]

open access: yesPLoS Biology, 2010
The Drosophila melanogaster sex hierarchy controls sexual differentiation of somatic cells via the activities of the terminal genes in the hierarchy, doublesex (dsx) and fruitless (fru).
Carmen C Robinett   +3 more
doaj   +1 more source

Boards of Directors and Governance Systems: A Practical Guide for Non-Governmental Organizations [PDF]

open access: yes, 2015
This guide was originally released in Spanish in 2014, as a practical tool for strengthening boards of directors of non-governmental organizations (NGOs) in Latin America.
Martha Farmelo
core  

Eddington & Uncertainty

open access: yes, 2003
Sir Arthur Eddington is considered one of the greatest astrophysicist of the twentieth century and yet he gained a stigma when, in the 1930s, he embarked on a quest to develop a unified theory of gravity and quantum mechanics.
Durham, Ian T.
core   +1 more source

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

open access: yesAdvanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr   +9 more
wiley   +1 more source

The cranial, mandibular, and hyoid anatomy of softshell turtles (Trionychidae): A revised character list for phylogenetic analysis

open access: yesThe Anatomical Record, EarlyView.
Abstract Softshell turtles (Pan‐Trionychidae) are an early branching clade of hidden‐necked turtles (Cryptodira) with a rich fossil record extending back to the Early Cretaceous. The evolutionary history of softshell turtles is still unresolved because of their conservative morphology combined with high levels of polymorphism related to morphological ...
Léa C. Girard, Walter G. Joyce
wiley   +1 more source

The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila

open access: yesNature Communications, 2017
fruitless (fru) is an important sex-determinant gene that controls the expression of neuroanatomical sex differences in Drosophila. Here the authors report that a core-promoter factor, TRF2, suppresses a male-type neurite specification through direct ...
Zahid Sadek Chowdhury   +2 more
doaj   +1 more source

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane   +33 more
wiley   +1 more source

Sex peptide targets distinct higher order processing neurons in the brain to induce the female post-mating response

open access: yeseLife
Sex peptide (SP) transferred during mating induces female post-mating responses including refractoriness to re-mate and increased oviposition in Drosophila. Yet, where SP-target neurons reside remained uncertain. Here, we show that expression of membrane-
Mohanakarthik P Nallasivan   +3 more
doaj   +1 more source

Interacting, but not contributing: fruitless news crowdsourcing in Spain

open access: yesEstudios sobre el Mensaje Periodístico, 2019
Trusting the audience to contribute data, a practice called crowdsourcing, is one of several procedures of contemporary data journalism. While previous research has embraced the idea of crowdsourcing as a transparent way of engaging the audience, the ...
Ester Appelgren, Ramón Salaverría
doaj   +1 more source

Recurring ethanol exposure induces disinhibited courtship in Drosophila. [PDF]

open access: yesPLoS ONE, 2008
Alcohol has a strong causal relationship with sexual arousal and disinhibited sexual behavior in humans; however, the physiological support for this notion is largely lacking and thus a suitable animal model to address this issue is instrumental.
Hyun-Gwan Lee   +3 more
doaj   +1 more source

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