Background Experimental and epidemiological studies show that bergamot polyphenolic fraction (BPF) ameliorates the serum lipemic profile, normalizes blood pressure and improves non alcoholic fatty liver disease in patients suffering from metabolic ...
Vincenzo Musolino+17 more
doaj +1 more source
Molecular pathology of the FSH receptor: New insights into FSH physiology [PDF]
Manipulations of mouse genome have helped to elucidate gonadotrophin function but important differences subsist between rodent and human reproduction. Studies of patients with mutations of gonadotrophins or gonadotrophin receptors genes allow understanding their physiological effects in humans.
Anne Bachelot+7 more
openaire +3 more sources
Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H.+4 more
core +1 more source
Some Hormonal Assay in Toxoplasma Infected University Students [PDF]
Background: Toxoplsma is a parasite with a global distribution that infect both human and animal, most of human toxoplasmosis is chronic infection. Chronic toxoplasmosis can affect human behavioral and hormonal status.
Fidan F. Ahmed+2 more
doaj +1 more source
Association between Bovine GDF9 SNPs and Calving Rate (Superovulation) in Holstein-Friesian Cows [PDF]
The present study aimed to assess the relationship of Growth Differentiation Factor 9 (GDF9) genotypes with calving rate, Follicle-stimulating hormone (FSH), and Estradiol (E2) in the Iraqi Holstein-Friesian breed.
S. Rasheed, L. Younis, Q. Aboud
doaj +1 more source
Gonadotropins in the Russian Sturgeon: Their Role in Steroid Secretion and the Effect of Hormonal Treatment on Their Secretion. [PDF]
In the reproduction process of male and female fish, pituitary derived gonadotropins (GTHs) play a key role. To be able to specifically investigate certain functions of Luteinizing (LH) and Follicle stimulating hormone (FSH) in Russian sturgeon ...
Aizen, Joseph+8 more
core +3 more sources
Pharmacogenetics of FSH Action in the Male [PDF]
Male infertility is a major contributor to couple infertility, however in most cases it remains "idiopathic" and putative treatment regimens are lacking. This leads to a scenario in which intra-cytoplasmic spermatozoa injection (ICSI) is widely used in idiopathic male infertility, though the treatment burden is high for the couple and it entails ...
Lina Pérez Lanuza+2 more
openaire +4 more sources
FSH-blocking therapeutic for osteoporosis
Pharmacological and genetic studies over the past decade have established the follicle-stimulating hormone (FSH) as an actionable target for diseases affecting millions, namely osteoporosis, obesity, and Alzheimer’s disease. Blocking FSH action prevents bone loss, fat gain, and neurodegeneration in mice.
Funda Korkmaz+45 more
openaire +3 more sources
The role of FSH and TGF-β superfamily in follicle atresia
Most of the mammalian follicles undergo a degenerative process called “follicle atresia”. Apoptosis of granulosa cells is the main characteristic of follicle atresia.
Yulan Chu, Ya-Ru Xu, Wan-Xi Yang, Yi Sun
semanticscholar +1 more source
Perturbing Microtubule Integrity Blocks AMP-Activated Protein Kinase-Induced Meiotic Resumption in Cultured Mouse Oocytes [PDF]
The oocyte meiotic spindle is comprised of microtubules (MT) that bind chromatin and regulate both metaphase plate formation and karyokinesis during meiotic maturation; however, little information is known about their role in meiosis reinitiation.
Downs, Stephen, Ya, Ru
core +2 more sources