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Are the FTO Gene Polymorphisms Associated with Colorectal Cancer? A Meta-analysis
Journal of Gastrointestinal Cancer, 2021Colorectal cancer (CRC) is reported to be associated with some gene polymorphisms. However, the effect of the fat mass and obesity associated (FTO) gene on colorectal cancer is not yet clear. This meta-analysis aimed to investigate the association of the FTO gene polymorphism and colorectal cancer.PubMed, Web of science, Scopus, and Embase were ...
Maryam, Gholamalizadeh +9 more
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Association analysis of FTO gene polymorphisms with obesity in Greek adults
Gene, 2017Nowadays, obesity is the greatest scourge worldwide, particularly for the developed countries and is a huge burden for the public health. Over the past decade, GWAS have revealed a number of genes associated with obesity. The fat mass and obesity associated (FTO) gene was the first one associated with obesity in a significant number of populations and ...
Yiannis Goutzelas +7 more
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Variation in the FTO Gene Influences Food Intake but not Energy Expenditure
Experimental and Clinical Endocrinology & Diabetes, 2008Polymorphisms in the FTO (fat mass- and obesity-associated) gene are associated with obesity. The mechanisms how genetic variation in this gene influences body weight are unknown. Body weight is determined by energy intake/storage and energy expenditure.
A, Haupt +8 more
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Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview
Molecular Biology Reports, 2014The FTO (fat mass and obesity-associated) gene has a strong linkage disequilibrium block, within which SNPs have been identified that are involved in the development of obesity. Recently some of these variants have also been associated with cancer. However, identification of the possible mechanisms that could explain these associations has proven to be
Marta Elena, Hernández-Caballero +1 more
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Common variant (rs9939609) in the FTO gene is associated with metabolic syndrome
Molecular Biology Reports, 2012Recent genome-wide association studies have showed that common variant (rs9939609) in fat mass and obesity associated (FTO) gene was significantly associated with type 2 diabetes through an effect on human body mass index/obesity. Further studies have suggested that this variant was also involved in the development of metabolic syndrome (MetS). However,
Donghao, Zhou +6 more
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Association between obesity‐related gene FTO and ADHD
Obesity, 2013ObjectiveAttention‐deficit/hyperactivity disorder (ADHD) is an etiologically complex heterogeneous behavioral disorder. Several studies have reported that ADHD subjects are more likely to be overweight/obese and that this comorbidity may be due to shared genetic factors.
Zia, Choudhry +6 more
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FTO gene polymorphisms and their role in acromegaly
Endocrine Abstracts, 2023Aleksandra Jawiarczyk-Przybyłowska +6 more
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FTO Gene Polymorphisms and Platelet Counts in a General Japanese Population
Journal of Investigative Medicine, 2012The fat mass and obesity-associated (FTO) gene has recently attracted attention as one of the obesity-related genes. Obesity-related gene polymorphisms may be associated with the development of atherothrombosis in relation to platelets.
Kazuhiko, Kotani +3 more
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The FTO Gene Is Associated With Adulthood Obesity in the Mexican Population
Obesity, 2008Common polymorphisms in the fat mass and obesity‐associated gene (FTO) have shown strong association with obesity in several populations. In the present study, we explored the association of FTO gene polymorphisms with obesity and other biochemical parameters in the Mexican population.
Marisela, Villalobos-Comparán +26 more
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Contributions of the FTO gene to fracture risk
Bone, 2009B.N.H. Tran +4 more
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