Results 111 to 120 of about 2,281 (190)

Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a β-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy. [PDF]

, 2011
OBJECTIVES: plasmid pB1000 bearing bla(ROB-1) is responsible for high-level β-lactam resistance in Haemophilus influenzae as well as in Pasteurella multocida and Haemophilus parasuis isolates from Spain.
San Millan, A, Giufré, M, Escudero, JA, Hidalgo, L, Gutierrez, B, Cerquetti, M, Gonzalez-Zorn, B, San Millan, Alvaro   +7 more
core   +1 more source

AIAA SciTech Forum 2025 [PDF]

Oblique Detonation Wave Engines (ODWEs) possess high prospects as an airbreathing propulsive system for high-speed vehicles due to shorter combustor length, high specific impulse, and high specific heat release.
Gewali, Sandip, Pandey, Anup, Adhikari, Sanjeev, Bhattrai, Sudip, Poudel, Nishchal   +4 more
core   +1 more source

A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility

BMC Microbiology, 2018
Background Identification and characterization of non-typeable Haemophilus influenzae (NTHi) with reduced susceptibility to β-lactam antibiotics due to mutations in penicillin binding protein 3 (PBP3) is a clinical challenge. We analyzed a blood isolate,
John Thegerström, Erika Matuschek, Yu-Ching Su, Kristian Riesbeck, Fredrik Resman   +4 more
doaj   +1 more source

Impaired envelope integrity in the absence of SanA is linked to increased Lipid II availability and an imbalance of FtsI and FtsW activities.

bioRxiv : the preprint server for biology
In gram-negative bacteria, the outer membrane (OM) acts in conjunction with the peptidoglycan (PG) cell wall as a barrier against physical, osmotic, and toxic environmental stresses including antibiotics. SanA, an inner membrane protein in Escherichia coli K-12, is required for vancomycin resistance at high temperatures (>42 °C) and we have previously ...
Carr, Joseph F., De Santiago, Carolina Basurto, Bhut, Shivani A., Warzecha, Daniel J., Robert Wei, Herrera, Carmen M., Stephen Trent, M., Nan, Beiyan, Mitchell, Angela M.   +8 more
openaire   +2 more sources

Studying the Dynamics of Relativistic Laser-Plasma Interaction on Thin Foils by Means of Fourier-Transform Spectral Interferometry [PDF]

, 2017
We apply Fourier-transform spectral interferometry (FTSI) to study the interaction of intense laser pulses with ultrathin targets. Ultrathin submicrometer-thick solid CH targets were shot at the PHELIX laser facility with an intensity in the mid to upper
J. Schreiber, Bagnoud, V., Wagner, F., F. Wagner, Brabetz, C., P. Hilz, B. Zielbauer, M. Haug, T. Schlegel, V. Bagnoud, Hornung, J., Roth, M., Schreiber, J., C. Brabetz, Zielbauer, B., Haug, M., M. Roth, Bagnoud, Vincent, Hilz, P., Schlegel, T., J. Hornung   +20 more
core   +1 more source

Whole-genome sequence analysis of morphological changes in Haemophilus influenzae after beta-lactam exposure

Journal of Global Antimicrobial Resistance
This report describes mutations in genes responsible for cell deformities in haemophili under beta-lactam pressure in vitro. Light and transmission electron microscopy confirmed a hypothesis regarding changes in the shape of haemophili that had become ...
Lucia Malisova, Vladislav Jakubu, Ibrahim Bitar, Daniel Krsek, Helena Zemlickova   +4 more
doaj   +1 more source

Emergence of antimicrobial resistance among invasive Haemophilus influenzae isolates in Belgium: epidemiology and genomic characterization

International Journal of Infectious Diseases
Introduction: Haemophilus influenzae (Hi) is a significant cause of invasive infections, including meningitis and sepsis. The emergence of resistant strains has prompted the World Health Organization to include Hi on its priority list for research and ...
Ms Magali Wautier, Dr Ricardo El Nouwar, Mr Benoit Prevost, Ms Farida Ahajjam, Ms Ariane Deplano, Ms Rim Fekkak, Dr Nicolas Yin, Dr Maya Hites, Prof Delphine Martiny   +8 more
doaj   +1 more source

Modeling of GyrA, MexB, FtsI, AtpD Protein Variants In Multidrug Resistant Acinetobacter baumannii

ABSTRACT Acinetobacter baumannii is a Gram-negative nosocomial pathogen known to manifest numerous drug resistances against major antibiotic classes. Compounded by its pathogenicity and virulence, it is considered globally as a top priority threat among the ESKAPE pathogens.
Nik Zakuan Hakim Nik Mohd Nazri, Siti Azma Jusoh, Kirnpal Kaur Banga Singh, Mohamad Izwan Ismail   +3 more
openaire   +1 more source

Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK

International Journal of COPD, 2017
Satyanarayana Maddi,1 Umme Kolsum,1 Sarah Jackson,1 Richard Barraclough,2 Barbara Maschera,3 Karen D Simpson,3 Thierry G Pascal,4 Serge Durviaux,4 Edith M Hessel,3 Dave Singh1 1Division of Infection, Immunity and Respiratory Medicine, Medicines ...
Maddi S, Kolsum U, Jackson S, Barraclough R, Maschera B, Simpson KD, Pascal TG, Durviaux S, Hessel EM, Singh D   +9 more
doaj  

Evolution of extended-spectrum β-lactamase-producing ST131 Escherichia coli at a single hospital over 15 years

Scientific Reports
Escherichia coli multi-locus sequence type ST131 is a globally distributed pandemic lineage that causes multidrug-resistant extra-intestinal infections. ST131 E.
Shu-Ting Cho, Emma G. Mills, Marissa P. Griffith, Hayley R. Nordstrom, Christi L. McElheny, Lee H. Harrison, Yohei Doi, Daria Van Tyne   +7 more
doaj   +1 more source