Results 21 to 30 of about 14,243 (169)

The Nucleoid Occlusion SlmA Protein Accelerates the Disassembly of the FtsZ Protein Polymers without Affecting Their GTPase Activity. [PDF]

open access: yesPLoS ONE, 2015
Division site selection is achieved in bacteria by different mechanisms, one of them being nucleoid occlusion, which prevents Z-ring assembly nearby the chromosome. Nucleoid occlusion in E.
Elisa J Cabré   +8 more
doaj   +1 more source

ZipA Uses a Two-Pronged FtsZ-Binding Mechanism Necessary for Cell Division

open access: yesmBio, 2021
In most bacteria, cell division is centrally organized by the FtsZ protein, which assembles into dynamic filaments at the division site along the cell membrane that interact with other key cell division proteins.
Todd A. Cameron   +4 more
doaj   +1 more source

SepG coordinates sporulation-specific cell division and nucleoid organization in Streptomyces coelicolor [PDF]

open access: yesOpen Biology, 2016
Bacterial cell division is a highly complex process that requires tight coordination between septum formation and chromosome replication and segregation.
Le Zhang   +3 more
doaj   +1 more source

Data_Sheet_2_Early origin and evolution of the FtsZ/tubulin protein family.ZIP

open access: yes, 2023
The origin of the FtsZ/tubulin protein family was extremely relevant for life since these proteins are present in nearly all organisms, carrying out essential functions such as cell division or forming a major part of the cytoskeleton in eukaryotes ...
Damien P. Devos (10828695)   +5 more
core   +1 more source

Data_Sheet_1_Early origin and evolution of the FtsZ/tubulin protein family.PDF

open access: yes, 2023
The origin of the FtsZ/tubulin protein family was extremely relevant for life since these proteins are present in nearly all organisms, carrying out essential functions such as cell division or forming a major part of the cytoskeleton in eukaryotes ...
Damien P. Devos (10828695)   +5 more
core   +1 more source

Functional Characterization of the Cell Division Gene Cluster of the Wall-less Bacterium Mycoplasma genitalium

open access: yesFrontiers in Microbiology, 2021
It is well-established that FtsZ drives peptidoglycan synthesis at the division site in walled bacteria. However, the function and conservation of FtsZ in wall-less prokaryotes such as mycoplasmas are less clear.
Carlos Martínez-Torró   +10 more
doaj   +1 more source

SlmA antagonism of FtsZ assembly employs a two-pronged mechanism like MinCD. [PDF]

open access: yesPLoS Genetics, 2014
Assembly of the Z-ring over unsegregated nucleoids is prevented by a process called nucleoid occlusion (NO), which in Escherichia coli is partially mediated by SlmA.
Shishen Du, Joe Lutkenhaus
doaj   +1 more source

The Kil peptide of bacteriophage λ blocks Escherichia coli cytokinesis via ZipA-dependent inhibition of FtsZ assembly.

open access: yesPLoS Genetics, 2014
Assembly of the essential, tubulin-like FtsZ protein into a ring-shaped structure at the nascent division site determines the timing and position of cytokinesis in most bacteria and serves as a scaffold for recruitment of the cell division machinery ...
Daniel P Haeusser   +8 more
doaj   +1 more source

Recent Progress in the Development of Small-Molecule FtsZ Inhibitors as Chemical Tools for the Development of Novel Antibiotics

open access: yesAntibiotics, 2019
Antibiotics are potent pharmacological weapons against bacterial pathogens, nevertheless their efficacy is becoming compromised due to the worldwide emergence and spread of multidrug-resistant bacteria or “superbugs”. Antibiotic resistance is
Laura Carro
doaj   +1 more source

The Search for Antibacterial Inhibitors Targeting Cell Division Protein FtsZ at Its Nucleotide and Allosteric Binding Sites

open access: yes, 2022
The global spread of bacterial antimicrobial resistance is associated to millions of deaths from bacterial infections per year, many of which were previously treatable.
Lidia Araújo-Bazán   +15 more
core   +1 more source

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