Results 31 to 40 of about 9,319 (176)
Frontiers in Microbiology, 2021 It is well-established that FtsZ drives peptidoglycan synthesis at the division site in walled bacteria. However, the function and conservation of FtsZ in wall-less prokaryotes such as mycoplasmas are less clear.
Carlos Martínez-Torró +10 more
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Investigation of Regulation of FtsZ Assembly by SulA and Development of a Model for FtsZ Polymerization [PDF]
Journal of Bacteriology, 2008 ABSTRACTInEscherichia coliFtsZ organizes into a cytoskeletal ring structure, the Z ring, which effects cell division. FtsZ is a GTPase, but the free energy of GTP hydrolysis does not appear to be used for generation of the constriction force, leaving open the question of the function of the GTPase activity of FtsZ.
Alex, Dajkovic +2 more
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Mutations in ftsZ that confer resistance to SulA affect the interaction of FtsZ with GTP [PDF]
Journal of Bacteriology, 1994 Mutations in the essential cell division gene ftsZ confer resistance to SulA, a cell division inhibitor that is induced as part of the SOS response. In this study we have purified and characterized the gene products of six of these mutant ftsZ alleles, ftsZ1, ftsZ2, ftsZ3, ftsZ9, ftsZ100, and ftsZ114, and compared their properties to those of the wild ...
K, Dai +3 more
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Cell division and transcription of ftsZ [PDF]
Journal of Bacteriology, 1993 For normal cell division, the ftsZ gene must be transcribed from a number of promoters that are located within the proximal upstream genes (ddlB, ftsQ, and ftsA). We show that the main promoters have identical responses to changes in growth rate, i.e., under all conditions, the frequency of transcription per septum formed is approximately constant and ...
R W, Smith, M, Masters, W D, Donachie
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SlmA antagonism of FtsZ assembly employs a two-pronged mechanism like MinCD. [PDF]
PLoS Genetics, 2014 Assembly of the Z-ring over unsegregated nucleoids is prevented by a process called nucleoid occlusion (NO), which in Escherichia coli is partially mediated by SlmA.
Shishen Du, Joe Lutkenhaus
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PLoS Genetics, 2014 Assembly of the essential, tubulin-like FtsZ protein into a ring-shaped structure at the nascent division site determines the timing and position of cytokinesis in most bacteria and serves as a scaffold for recruitment of the cell division machinery ...
Daniel P Haeusser +8 more
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Antibiotics, 2019 Antibiotics are potent pharmacological weapons against bacterial pathogens, nevertheless their efficacy is becoming compromised due to the worldwide emergence and spread of multidrug-resistant bacteria or “superbugs”. Antibiotic resistance is
Laura Carro
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Torsion and curvature of FtsZ filaments [PDF]
Soft Matter, 2014 FtsZ filaments participate in bacterial cell division, but it is still not clear how their dynamic polymerization and shape exert force on the underlying membrane. We present a theoretical description of individual filaments that incorporates information from molecular dynamic simulations. The structure of the crystallized Methanococcus jannaschii FtsZ
González de Prado Salas, Pablo +8 more
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ClpXP protease degrades the cytoskeletal protein, FtsZ, and modulates FtsZ polymer dynamics [PDF]
Proceedings of the National Academy of Sciences, 2009 FtsZ is the major cytoskeletal protein in bacteria and a tubulin homologue. It polymerizes and forms a ring where constriction occurs to divide the cell. We found that FtsZ is degraded by E. coli ClpXP, an ATP-dependent protease.
Jodi L, Camberg +2 more
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PLoS ONE, 2014 The Deinococcus radiodurans genome encodes homologues of divisome proteins including FtsZ and FtsA. FtsZ of this bacterium (Dr-FtsZ) has been recently characterized. In this paper, we study FtsA of D.
Kruti Modi, Hari S Misra
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