Results 1 to 10 of about 286,033 (295)
Checks and Balances in Bacterial Cell Division [PDF]
mBio, 2019 Assembly of the division machinery in Gram-negative and Gram-positive bacteria occurs in two time-dependent steps. First, the FtsZ proto-ring localizes at midcell including some FtsN molecules. Subsequently, the proteins that catalyze and regulate septal
Tanneke den Blaauwen, Joen Luirink
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Targeting Bacterial Cell Division: A Binding Site-Centered Approach to the Most Promising Inhibitors of the Essential Protein FtsZ [PDF]
Antibiotics, 2020 Binary fission is the most common mode of bacterial cell division and is mediated by a multiprotein complex denominated the divisome. The constriction of the Z-ring splits the mother bacterial cell into two daughter cells of the same size.
Andrea Casiraghi +3 more
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Bacterial cell division proteins as antibiotic targets [PDF]
Bioorganic Chemistry, 2014 Proteins involved in bacterial cell division often do not have a counterpart in eukaryotic cells and they are essential for the survival of the bacteria. The genetic accessibility of many bacterial species in combination with the Green Fluorescence Protein revolution to study localization of proteins and the availability of crystal structures has ...
Tanneke Den Blaauwen +2 more
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Bacterial cell division at a glance. [PDF]
J Cell Sci, 2020 ABSTRACT Bacterial cell division is initiated by the midcell assembly of polymers of the tubulin-like GTPase FtsZ. The FtsZ ring (Z-ring) is a discontinuous structure made of dynamic patches of FtsZ that undergo treadmilling motion. Roughly a dozen additional essential proteins are recruited to the division site by the dynamic Z-ring ...
Mahone CR, Goley ED.
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Finding New Fundamental Pieces for the Bacterial Cell Division Puzzle [PDF]
mBio, 2022 The division of bacterial cells into two daughter cells requires a precise balance of more than a dozen highly conserved proteins that coordinate chromosome segregation with the synthesis of the novel cell envelope.
Dorte Frees, Hanne Ingmer
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KilR of E. coli Rac prophage is a dual inhibitor of bacterial cell division and elongation machineries [PDF]
mSphereBacterial cryptic prophages not only encode genes that reduce the viability of the host upon induction but also contribute to host survival during stressful conditions.
Anusha Marepalli +2 more
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Simulations suggest a constrictive force is required for Gram-negative bacterial cell division [PDF]
Nature Communications, 2019 It is unclear whether a constrictive force is exerted on the membrane from inside during bacterial cell division, or cell wall remodeling alone drives membrane constriction from outside.
Lam T. Nguyen +7 more
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Segrosome complex formation during DNA trafficking in bacterial cell division [PDF]
Frontiers in Molecular Biosciences, 2016 Bacterial extrachromosomal DNAs often contribute to virulence in pathogenic organisms or facilitate adaptation to particular environments. The transmission of genetic information from one generation to the next requires sufficient partitioning of DNA ...
Maria A. Oliva
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FtsZ-mediated fission of a cuboid bacterial symbiont
iScience, 2022 Summary: Less than a handful of cuboid and squared cells have been described in nature, which makes them a rarity. Here, we show how Candidatus Thiosymbion cuboideus, a cube-like gammaproteobacterium, reproduces on the surface of marine free-living ...
Philipp M. Weber +8 more
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Bacterial flagellation and cell division [PDF]
Genes to Cells, 1998 The peritrichous flagella of Salmonella are synthesized and function through many cell generations. There are two different aspects in the relationship between flagellar biogenesis and cell division. Filament growth is independent from the cell cycle and the length of filaments appear to be locally controlled at each flagellar base, whereas the number ...
S I, Aizawa, T, Kubori
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