Results 91 to 100 of about 6,427 (219)

Genome-wide Linkage Scan in Fuchs Endothelial Corneal Dystrophy [PDF]

Investigative Opthalmology & Visual Science, 2009
To perform a genome-wide linkage screen with a single-nucleotide polymorphism (SNP) linkage panel to identify regions of genetic linkage in Fuchs endothelial corneal dystrophy (FECD) and to analyze affected individuals for mutations in the COL8A2 gene.Ninety-two individuals from 22 families with FECD were identified from our multiplex FECD family ...
Natalie A, Afshari, Yi-Ju, Li, Margaret A, Pericak-Vance, Simon, Gregory, Gordon K, Klintworth   +4 more
openaire   +2 more sources

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, Volume 8, Issue 9, September 2025.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Simultaneous phacoemulsification, lens implantation and endothelial keratoplasty: Triple procedure [PDF]

, 2011
Introduction. Simultaneous Descemet stripping endothelial keratoplasty, phacoemulsification, and intraocular lens implantation are indicated in Fuchs’ dystrophy with associated cataract.
Jovanović Vesna, Nikolić Ljubiša
core   +1 more source

Normative Values on Stromal Curvature, Power and Corneal‐Stromal Curvature Ratios From a Hybrid AS‐OCT

Clinical &Experimental Ophthalmology, Volume 53, Issue 7, Page 746-755, September/October 2025.
ABSTRACT Background To establish normative values for stromal curvature and its relationships to anterior and posterior curvature. Methods Retrospective observational study. Data were obtained from 75 eyes of cataract surgery patients using a high‐resolution anterior segment optical coherence tomograph (AS‐OCT; MS‐39, CSO).
Jascha A. Wendelstein, Arianna Grendele, Achim Langenbucher, Alice Galzignato, Catarina Praefke Coutinho, Seth Pantanelli, Kamran M. Riaz, Giacomo Savini   +7 more
wiley   +1 more source

Biocompatibility of Genetically‐Engineered Pig Cornea in Corneal Xenotransplantation: Preliminary In Vitro Study

Xenotransplantation, Volume 32, Issue 5, September/October 2025.
ABSTRACT Introduction We aimed to evaluate biophysical compatibility of corneal endothelial cells in genetically‐engineered (GE) pigs to identify the best candidate for in vivo nonhuman primate (NHP) study and to collect baseline data for future clinical trials from a biological function perspective.
Seung Hyeun Lee, Chung Young Kim, Jin Suk Ryu, Dong Hee Choi, Chang Ho Yoon, Chung‐Gyu Park, Kimyung Choi, Hyunil Kim, Mee Kum Kim   +8 more
wiley   +1 more source

Corneal amyloid staining after trypan blue in Descemet's membrane endothelial keratoplasty

American Journal of Ophthalmology Case Reports
Purpose: This case report seeks to highlight impressive photographs of amyloid staining with trypan blue that persisted after DMEK surgery with 3 years follow-up. This has only been reported in the literature twice previously, and may have contributed to
Alexandra Klejn, Robin G. Abell
doaj   +1 more source

Corneal endothelial cell dysfunction: etiologies and management

Therapeutic Advances in Ophthalmology, 2018
A transparent cornea is essential for the formation of a clear image on the retina. The human cornea is arranged into well-organized layers, and each layer plays a significant role in maintaining the transparency and viability of the tissue.
Sepehr Feizi
doaj   +1 more source

Bullous keratopathy: etiopathogenesis and treatment [PDF]

, 2008
Bullous keratopathy is characterized by corneal stromal edema with epithelial or subepithelial bullae due to cell loss and endothelial decompensation.
Campos, Mauro Silveira de Queiroz, Farias, Charles Costa de, Gomes, José Álvaro Pereira, Gonçalves, Eliana Domingues, Paris, Fabiana dos Santos   +4 more
core   +2 more sources

Presbyopia Correction in Lens Replacement Surgery: A Review

Clinical &Experimental Ophthalmology, Volume 53, Issue 6, Page 668-681, August 2025.
ABSTRACT Presbyopia affects approximately 1.8 billion individuals globally, posing significant challenges as life expectancy and near‐vision demands, particularly with mobile phone use, grow. Addressing presbyopia during lens replacement surgery has become a key focus for cataract surgeons, aiming to reduce dependence on corrective eyewear. This review
Benjamin Stern, Damien Gatinel
wiley   +1 more source

Long-term results of corneal wedge resections for the correction of high astigmatism [PDF]

, 1990
We retrospectively evaluated 41 corneal wedge resections, performed for the correction of high astigmatism in 40 patients who were spectacle and contact lens intolerant. Keratometric astigmatism decreased from an average of 11.7 diopters (range 5 to 22.5
Beekhuis, W.H. (Houdijn), Hoppenreijs, V.P.T. (Vincent), Rij, G. (Gabriel) van, Rijneveld, W.J. (Wilhelmina), Rinkel-Van Driel, E. (E.)   +4 more
core   +1 more source