Results 101 to 110 of about 609,036 (191)

Mutagenesis of mitochondrial DNA in Fuchs endothelial corneal dystrophy

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2014
Fuchs endothelial corneal dystrophy (FECD) is an age-related, slowly progressive disease, which may lead to loss of vision resulting from apoptosis of corneal endothelial (CE) cells, dysfunction of Descemet membrane (DM) and corneal edema. A growing body of evidence suggests that oxidative stress may play a major role in the pathogenesis of FECD and ...
Czarny, P, Seda, A, Wielgorski, M, Binczyk, E, Markiewicz, B, Kasprzak, E, Jimenez-Garcia, Manuel Pedro, Grabska-Liberek, I, Pawlowska, E, Blasiak, Janusz, Szaflik, J, Szaflik, JP   +11 more
openaire   +3 more sources

Secondary sulcus IOL implantation for presbyopia correction following Descemet Membrane Endothelial Keratoplasty

American Journal of Ophthalmology Case Reports
Purpose: Report a case where the patient desired spectacle independence after phacoemulsification and Descemet membrane endothelial keratoplasty (DMEK) due to Fuchs’ endothelial dystrophy.
Luiza Moschetta Zimmermann, Guilherme Vieira Peixoto, Júlia Margoni Biluca, José Maurílio Tavares de Lucena, Ricardo Menon Nosé   +4 more
doaj   +1 more source

Medical and Semi-surgical Treatments for Fuchs Endothelial Corneal Dystrophy

, 2018
Unraveling the genetic mechanisms of Fuchs endothelial corneal dystrophy has opened new possibilities for future targeted medical therapy of the disease.
Michael Fautsch, Keith Baratz, Sanjay Patel, Baratz, Keith H., Wacker, Katrin, Fautsch, Michael, Katrin Wacker, Patel, Sanjay V.   +7 more
core   +1 more source

Evaluation of endothelial/Descemet membrane complex of eye bank donor corneas using enhanced depth imaging optical coherence tomography

Clinical Ophthalmology, 2019
Zeba A Syed,1 Gustavo Rosa Gameiro,1 Marco Ruggeri,1 Amr Elsawy,1,2 Ibrahim Sayed-Ahmed,1 Vatookarn Roongpoovapatr,1 Mohamed Abdel-Mottaleb,2 Mohamed Abou Shousha11Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller ...
Syed ZA, Gameiro GR, Ruggeri M, Elsawy A, Sayed-Ahmed I, Roongpoovapatr V, Abdel-Mottaleb M, Abou Shousha M   +7 more
doaj  

Fibrocytes in Fuchs' Endothelial Corneal Dystrophy

, 2017
Fuchs' endothelial corneal dystrophy (FECD) is a degenerative eye disorder affecting 4% of Americans older than 40. It is the leading indication for corneal endothelial (CE) transplantation for which there is a global donor shortage.
De Roo, An-Katrien, Foets, Beatrijs, Wouters, Jasper, van den Oord, Joost, Govaere, Olivier   +4 more
core   +1 more source

Regulation of Oxidative Stress in Corneal Endothelial Cells by Prdx6

Antioxidants, 2018
The inner layer of the cornea, the corneal endothelium, is post-mitotic and unable to regenerate if damaged. The corneal endothelium is one of the most transplanted tissues in the body.
Matthew Lovatt, Khadijah Adnan, Gary S. L. Peh, Jodhbir S. Mehta   +3 more
doaj   +1 more source

Mini descemet membrane stripping (m-DMES) in patients with Fuchs’ endothelial dystrophy: A new method

, 2017
We present two cases with focal corneal edema due to Fuchs’ endothelial dystrophy that were successfully treated with mini Descemet membrane stripping (m-DMES) (diameter of 3–4 mm; at the area of preexisting focal corneal edema) without endothelial ...
Kymionis, G.D., Grentzelos, M.A., Tsoulnaras, K.I., Naoumidi, I., Kontadakis, G.A., Petrelli, M.K., Liakopoulos, D.A.   +6 more
core   +1 more source

Fenofibrate in ophthalmology: therapeutic efficacy and mechanisms

Journal of Pharmacy & Pharmaceutical Sciences
Ophthalmic diseases are a growing global cause of visual impairment, driven by population aging and the rising prevalence of diabetes mellitus. Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist widely used for dyslipidemia ...
Sean Chung-Hei Ho, Isabelle Xin Yu Lee, Chang Liu, Mingyi Yu, Hong Chang Tan, Gavin Siew Wei Tan, Yu-Chi Liu, Yu-Chi Liu   +7 more
doaj   +1 more source

Dual corneal involvement by endothelial and epithelial corneal dystrophies in Steinert's disease: A case of triple dystrophy

Introduction: A case of dual corneal involvement due to Fuchs endothelial corneal dystrophy and epithelial basement membrane corneal dystrophy in a patient with Steinert's myotonic dystrophy type 1 is described, and a literature review on the triple ...
Gargallo Benedicto, Amparo, Duch Samper, Antonio Miguel, Clemente Tomás, Rodrigo, Perez-Torregrosa, V. T.   +3 more
core   +1 more source

Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae

Clinical Ophthalmology, 2020
Bu Ki Kim,1 Young Taek Chung2 1Onnuri Smile Eye Clinic, Gangnam-Daero 65 Gil, Seoul, Seocho-gu, Republic of Korea; 2Onnuri Eye Hospital, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaCorrespondence: Young Taek Chung 325, Baekje-Daero,
Kim BK, Chung YT
doaj