Results 81 to 90 of about 609,036 (191)

Fuchs Endothelial Corneal Dystrophy

This post hoc secondary analysis of the Women’s Health Initiative study assesses whether randomization to hormone therapy use was associated with subsequent incident Fuchs endothelial corneal dystrophy.
Millen, Amy E., Nie, Jing, Wactawski-Wende, Jean, Andrews, Chris A., Shadyab, Aladdin H., Wallace, Robert B., Patel, Sangita P.   +6 more
openaire   +2 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

, 2023
Fuchs’ corneal endothelial dystrophy (FECD) is a major cause of vision loss. Corneal transplantation is the only effective curative treatment, but this surgery has limitations. A pharmacological intervention would complement surgery and be beneficial for
Mahboubeh Kheirabadi (2026798), V. Vinod Mootha (6264278), Jiaxin Hu (1327875), Ziqing Qian (1285203), Xiulong Shen (1655650), David R. Corey (1327872), Matthew D. Streeter (1754443)   +6 more
core   +1 more source

Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging

Ophthalmology Science
Purpose: To evaluate changes in corneal densitometry and optical aberrations using Scheimpflug imaging in early Fuchs endothelial corneal dystrophy (FECD) and to assess their association with CTG trinucleotide repeat expansion.
Stanley S.J. Poh, MBBS, Kai Yuan Tey, MBBS, Gary S.L. Peh, PhD, Dawn J.H. Neo, MSc, Hla Myint Htoon, PhD, Evan K.L. Lee, Yu Qiang Soh, MBBS, V Vinod Mootha, MD, Jodhbir S. Mehta, PhD   +8 more
doaj   +1 more source

Waiting list distribution with indications for corneal transplantation.

, 2018
This figure shows the distribution of the corneal graft waiting list with indications for corneal transplantation (Fuchs' dystrophy, keratoconus, bullous keratopathy, trauma, rejection, and others) from 2004 to 2015 in 735 cases. The most common surgical
Tobias Röck (5447411), Karl U. Bartz-Schmidt (167658), Daniel Röck (5447414)   +2 more
core   +1 more source

Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs

Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Objective To compare unsedated noncontact specular microscopy imaging techniques for the canine corneal endothelium and identify the most effective technique. Animals Studied Nineteen eyes of 10 systemically healthy, staff‐owned dogs with clinically normal corneas were studied.
Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo   +4 more
wiley   +1 more source

Comparison of Descemet Stripping Automated Endothelial Keratoplasty and Penetrating Keratoplasty in a Patient with Fuchs Endothelial Dystrophy

, 2013
To report a patient with Fuchs endothelial dystrophy (FED) who underwent Descemet stripping automated endothelial keratoplasty (DSAEK) on one eye and penetrating keratoplasty (PK) on the fellow eye.
Alime Güneş, Anıl Kubaloğlu, Kansu Tahir Bozkurt   +2 more
core   +1 more source

Corneal endothelial cell dysfunction: etiologies and management

Therapeutic Advances in Ophthalmology, 2018
A transparent cornea is essential for the formation of a clear image on the retina. The human cornea is arranged into well-organized layers, and each layer plays a significant role in maintaining the transparency and viability of the tissue.
Sepehr Feizi
doaj   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

Corneal amyloid staining after trypan blue in Descemet's membrane endothelial keratoplasty

American Journal of Ophthalmology Case Reports
Purpose: This case report seeks to highlight impressive photographs of amyloid staining with trypan blue that persisted after DMEK surgery with 3 years follow-up. This has only been reported in the literature twice previously, and may have contributed to
Alexandra Klejn, Robin G. Abell
doaj   +1 more source