Results 61 to 70 of about 609,036 (191)

Advancing Treatment of Degenerative Eye Diseases at the Nanoscale

Smart Medicine, Volume 5, Issue 4, August 2026.
Nanotherapeutics possess the potential to overcome longstanding bottlenecks in treating degenerative ophthalmic diseases. With a highly tunable surface chemistry, nanotechnology platforms can be customized to navigate specific anatomical barriers in the eye and target pathways of diseases.
Li Yao Jin, Evashiniee G. P. Selvam, Qinsong Mei, Chi D. Luu, Yeannie H. Y. Yap, Daniel B. L. Teh   +5 more
wiley   +1 more source

First identification of a triple corneal dystrophy association: keratoconus, epithelial basement membrane corneal dystrophy and fuchs' endothelial corneal dystrophy [PDF]

, 2014
Purpose: To report the observation of a triple corneal dystrophy association consisting of keratoconus (KC), epithelial basement membrane corneal dystrophy (EBMCD) and Fuchs' endothelial corneal dystrophy (FECD).
Frederik Raiskup, Traversi, C., Caterina Lo Rizzo, Mazzotta, C., Cosimo Mazzotta, Raiskup, F., Claudio Traversi, Renieri, A., Alessandra Renieri, Rizzo, C. l.   +9 more
core   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

Acta Ophthalmologica, Volume 104, Issue 5, Page e516-e529, August 2026.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg, Jithmi Weliwitage, Marie von Berg, Silvia Schrittenlocher, Simona Schlereth, Claus Cursiefen, Björn Bachmann   +6 more
wiley   +1 more source

Axenfeld-Rieger anomaly and corneal endothelial dystrophy: a case series Anomalia de Axenfeld-Rieger e distrofia corneana endotelial: uma série de casos

Revista Brasileira de Oftalmologia, 2008
Report of a study of a family with a remarkable combination of endothelial corneal dystrophy, and anterior chamber dysgenesis classified as Axenfeld-Rieger anomaly. A 56 year-old female had blurred vision complaints.
Mariana Borges Oliveira, Roberto dos Santos Mitraud, Riuitiro Yamane   +2 more
doaj   +1 more source

Emerging Innovations in the Treatment of Fuchs Endothelial Corneal Dystrophy: A Narrative Review. [PDF]

Med Sci (Basel)
Fuchs endothelial corneal dystrophy (FECD) is the leading cause of endothelial failure requiring keratoplasty in industrialised nations. Descemet membrane endothelial keratoplasty (DMEK) has become the gold-standard surgical therapy, yet it is ...
Niestrata M, Jackson J, Bazeer S, Gong MA, Ashena Z.   +4 more
europepmc   +2 more sources

Ray‐Tracing‐Based Intraocular Lens Power Calculation in Combined Cataract Surgery and Descemet Membrane Endothelial Keratoplasty

Clinical &Experimental Ophthalmology, Volume 54, Issue 6, Page 769-778, August 2026.
ABSTRACT Background To compare the predictive accuracy of ray tracing‐based intraocular lens (IOL) power calculation formulas with the Barrett Universal II (BUII) formula in eyes with Fuchs endothelial corneal dystrophy (FECD) undergoing combined cataract surgery and Descemet membrane endothelial keratoplasty (triple DMEK).
Jan O. Weber, Klemens P. Kaiser, Jascha A. Wendelstein, H. Burkhard Dick, Thomas Kohnen, Ingo Schmack   +5 more
wiley   +1 more source

In Vivo Imaging of Corneal Endothelial Dystrophy in Boston Terriers: A Spontaneous, Canine Model for Fuchs' Endothelial Corneal DystrophyA Canine Model of Fuchs' Endothelial Corneal Dystrophy [PDF]

, 2016
PURPOSE: Boston Terriers (BTs) have a greater prevalence of corneal endothelial dystrophy (CED), in comparison to other canine breeds. Similar to Fuchs' endothelial corneal dystrophy (FECD), this condition is characterized by endothelial cell ...
Thomasy, Sara M, Thomasy, S., Cortés Novoa, Dennis Enrique, Hoehn, A., Calderon, A., Murphy, C., Hoehn, Alyssa L, Li, Jennifer Y, Calderon, Allison C, Li, J., Murphy, Christopher J, Cortes, Dennis E   +11 more
core   +1 more source

Retained Descemet’s membrane following penetrating keratoplasty for Fuchs’ endothelial dystrophy: a case report of a post-operative complication

Clinical Ophthalmology, 2013
Katherine McVeigh,1,3,* Kurt Spiteri Cornish,3 Aravind R Reddy,3 Georgios Vakros2,3,* 1Eye Clinic, Royal United Bath Hospital, Bath, UK; 2Birmingham Midland Eye Centre, Birmingham City Hospital, Birmingham, UK; 3Ophthalmology Department, Aberdeen Royal ...
McVeigh K, Spiteri Cornish K, Reddy AR, Vakros G   +3 more
doaj  

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, Volume 13, Issue 41, 22 July 2026.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Evolving Techniques and Indications of Descemet Membrane Endothelial Keratoplasty

Türk Oftalmoloji Dergisi, 2021
Endothelial keratoplasty has replaced traditional penetrating keratoplasty for the treatment of corneal endothelial dysfunction. It offers faster, more predictable, stable visual recovery and low rejection rates while the surgery itself is less invasive.
Özlem Evren Kemer, Emine Esra Karaca, Silke Oellerich, Gerrit Melles   +3 more
doaj   +1 more source