Results 41 to 50 of about 609,036 (191)

Fuchs Endothelial Corneal Dystrophy-Specific Questionnaire in Croatian: Visual Function and Corneal Health Status (V-FUCHS)

Acta Clinica Croatica
Fuchs endothelial corneal dystrophy (FECD) is a bilateral dystrophy of the cornea and the most common indication for corneal transplantation procedures.
Ivan Merdžo, Ivana Radman, Aida Kasumović, Miodrag Vojčić, Antonio Markotić, Nina Đumrukčić, Iva Krolo   +6 more
doaj   +1 more source

SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress

Scientific Reports, 2017
Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha, Sunita Chaurasia, Charanya Ramachandran, Sanhita Roy   +3 more
doaj   +1 more source

Fuchs Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy [PDF]

Cornea, 2014
The aim was to report 4 cases of Fuchs endothelial corneal dystrophy (FECD) in patients with an established diagnosis of myotonic dystrophy (DM) and suggest a mechanism for their association based on the known molecular genetics and potential pathophysiological parallels of DM and FECD.We reviewed all available medical records and pathology slides for ...
Devin, Gattey, Angela Y, Zhu, Anna, Stagner, Mark A, Terry, Albert S, Jun   +4 more
openaire   +2 more sources

Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

Nature Communications, 2017
Fuchs endothelial corneal dystrophy (FECD) is one of the most common reasons for corneal transplantation, and is known to cluster in families. Here, the authors discover new genetic loci associated with FECD with sex-specific effects and implications for
Natalie A. Afshari, Robert P. Igo, Nathan J. Morris, Dwight Stambolian, Shiwani Sharma, V. Lakshmi Pulagam, Steven Dunn, John F. Stamler, Barbara J. Truitt, Jacqueline Rimmler, Abraham Kuot, Christopher R. Croasdale, Xuejun Qin, Kathryn P. Burdon, S. Amer Riazuddin, Richard Mills, Sonja Klebe, Mollie A. Minear, Jiagang Zhao, Elmer Balajonda, George O. Rosenwasser, Keith H Baratz, V. Vinod Mootha, Sanjay V. Patel, Simon G. Gregory, Joan E. Bailey-Wilson, Marianne O. Price, Francis W. Price, Jamie E. Craig, John H. Fingert, John D. Gottsch, Anthony J. Aldave, Gordon K. Klintworth, Jonathan H. Lass, Yi-Ju Li, Sudha K. Iyengar   +35 more
doaj   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Corneal transplantation: Restoring sight to the blind

Acta Ophthalmologica, EarlyView.
Abstract Corneal blindness is one of the leading causes of vision loss worldwide. Transplantation of the cornea can restore vision and make blind patients see again. Corneal transplant surgery has undergone major evolution in recent decades with the advent of minimally invasive lamellar surgical approaches such as DMEK and DALK.
Claus Cursiefen
wiley   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Unilateral corneal endothelial dystrophy and anterior keratoconus

, 2007
PURPOSE: To describe a case of keratoconus and Fuchs' corneal endothelial dystrophy in the left eye with no corneal disease in the right eye. METHODS: A 64-year-old woman presented with visual impairment in her left eye; computer-assisted topographic ...
TOMMASI C., TRAVERSI C., TOSI G. M., BERNI E., MARTONE G., BALESTRAZZI A., NUTI E., G. Martone, E. Nuti, A. Balestrazzi, E. Berni, C. Traversi, G.M. Tosi, C. Tommasi   +13 more
core   +1 more source

Oxidative stress and cellular protein accumulation are present in keratoconus, macular corneal dystrophy, and Fuchs endothelial corneal dystrophy [PDF]

, 2023
The aim of the study was to investigate oxidative stress as well as cellular protein accumulation in corneal diseases including keratoconus (KC), macular corneal dystrophy (MCD), and Fuchs endothelial corneal dystrophy (FECD) at their primary affecting ...
Kryszan, Katarzyna, Kai Kaarniranta, Kaarniranta, Kai, Koskela, Ali, Iswariyaraja Sridevi Gurubaran, Linda Vottonen, Katarzyna Kryszan, Gurubaran, Iswariyaraja Sridevi, Ali Koskela, Felszeghy, Szabolcs, Szabolcs Felszeghy, Edward Wylegala, Wylęgała, Adam, Adam Wylegala, Vottonen, Linda, Wylegala, Edward   +15 more
core   +1 more source

Descemet membrane endothelial keratoplasty combined with secondary sulcus hydrophobic intraocular lens implantation

American Journal of Ophthalmology Case Reports
Purpose: To report a case of combined Descemet membrane endothelial keratoplasty (DMEK) and secondary sulcus hydrophobic intraocular lens (IOL) implantation for hyperopic correction in a pseudophakic eye with Fuchs’ endothelial corneal dystrophy ...
Colya N. Englisch, Philip Wakili, Clara E. Englisch, Karl T. Boden, Annekatrin Rickmann, Peter Szurman, André Messias   +6 more
doaj   +1 more source