Results 31 to 40 of about 609,036 (191)

MicroRNA of Epithelial to Mesenchymal Transition in Fuchs’ Endothelial Corneal Dystrophy

, 2022
Aim: a review of miRNA expression connected to epithelial mesenchymal transition studies in Fuchs’ endothelial corneal dystrophy (FECD). Methods: literature search strategy—PubMed central database, using “miRNA” or “microRNA&
Stunf Pukl, Spela, Spela Stunf Pukl
core   +1 more source

Review of the Literature: Surgery Indications for Fuchs' Endothelial Corneal Dystrophy. [PDF]

J Clin Med
Objectives: To provide an overview of the preoperative indications for endothelial graft in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: A comprehensive database search without date restrictions was performed in PubMed.
Tourabaly M, Knoeri J, Georgeon C, Borderie V.   +3 more
europepmc   +2 more sources

Shared modules of gene co-expression networks in Fuchs’ endothelial corneal dystrophy (FECD) patients with (RE+) and without (RE-) the TCF4 CTG18.1 expansion.

, 2023
Shared modules of gene co-expression networks in Fuchs’ endothelial corneal dystrophy (FECD) patients with (RE+) and without (RE-) the TCF4 CTG18.1 expansion.
V. Vinod Mootha (6264278), Ashwani Kumar (55732), Xunzhi Zhang (14631644), Adwait A. Sathe (6541643), Chao Xing (28961)   +4 more
core   +1 more source

Preclinical Models for Studying Fuchs Endothelial Corneal Dystrophy. [PDF]

Cells
Fuchs Endothelial Corneal Dystrophy (FECD) is a corneal endothelial disease that causes microenvironment alterations and endothelial cell loss, which leads to vision impairment. It has a high global prevalence, especially in elderly populations.
Sun F, Xi LWQ, Luu W, Enkhbat M, Neo D, Mehta JS, Peh GSL, Yim EKF.   +7 more
europepmc   +2 more sources

Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis

Progress in Retinal and Eye Research, 2021
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal endothelial dystrophy and the leading indication for corneal transplantation worldwide. FECD is characterized by the progressive decline of corneal endothelial cells (CECs) and the formation of extracellular matrix (ECM) excrescences in Descemet's membrane (DM), called guttae,
Stephan Ong Tone, Viridiana Kocaba, Myriam Böhm, Adam Wylegala, Tomas L. White, Ula V. Jurkunas   +5 more
openaire   +3 more sources

Femtosecond Laser-Assisted Cataract Surgery: Does It Improve Outcomes in Fuchs Endothelial Corneal Dystrophy?

, 2020
The role of femtosecond laser -assisted cataract surgery in patients with Fuchs endothelial corneal dystrophy remains poorly defined.
Koo, Ellen H, Ellen H. Koo
core   +1 more source

Cataract surgery in patients with Fuchs’ dystrophy and corneal decompensation indicated for Descemet's membrane endothelial keratoplasty

Scientific Reports, 2022
The availability of corneal donor tissue is limited in most developing countries. This study evaluated whether patients with coexisting cataract and Fuchs’ dystrophy with corneal decompensation awaiting Descemet’s membrane endothelial keratoplasty (DMEK)
Wei-Yi Chou, Yih-Shiuan Kuo, Pei-Yu Lin
doaj   +1 more source

Expression and Function of ZEB1 in the Cornea

Cells, 2021
ZEB1 is an important transcription factor for epithelial to mesenchymal transition (EMT) and in the regulation of cell differentiation and transformation.
Yingnan Zhang, Xiao Liu, Wei Liang, Douglas C. Dean, Lijun Zhang, Yongqing Liu   +5 more
doaj   +1 more source

Dataset on transcriptome profiling of corneal endothelium from patients with Fuchs endothelial corneal dystrophy

Data in Brief, 2019
Fuchs endothelial corneal dystrophy (FECD) is a bilateral inherited eye disease with advanced forms only treatable by corneal transplantation. The pathogenesis of FECD has not been worked out yet, however, trinucleotide repeat polymorphism CTG18.1 in the
Anastasia S. Nikitina, Alexandra V. Belodedova, Boris E. Malyugin, Elena I. Sharova, Elena S. Kostryukova, Andrey K. Larin, Vladimir A. Veselovsky, Olga P. Antonova, Liubov O. Skorodumova   +8 more
doaj   +1 more source

Phototherapeutic keratectomy for anterior stromal fibrosis following DMEK

American Journal of Ophthalmology Case Reports, 2020
Purpose: Anterior stromal fibrosis is often seen in advanced cases of Fuchs endothelial dystrophy or secondary endothelial insufficiency. As Descemet membrane endothelial keratoplasty (DMEK) can completely eliminate the corneal edema and the guttae in ...
Philip Maier, Thomas Reinhard
doaj   +1 more source