Results 21 to 30 of about 609,036 (191)

Fuchs Endothelial Corneal Dystrophy [PDF]

The Ocular Surface, 2010
Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive loss of corneal endothelial cells, thickening of Descement's membrane and deposition of extracellular matrix in the form of guttae. When the number of endothelial cells becomes critically low, the cornea swells and causes loss of vision. The clinical course of FECD usually spans
Hussain, Elhalis, Behrooz, Azizi, Ula V, Jurkunas   +2 more
openaire   +3 more sources

Exploring the histopathological signature of repeat-mediated Fuchs endothelial corneal dystrophy. [PDF]

Acta Ophthalmol
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Kladny AS, Bhattacharyya N, Abreu Costa M, Tuft SJ, Thaung C, Davidson AE.   +5 more
europepmc   +2 more sources

Fuchs Endothelial Corneal Dystrophy [PDF]

JAMA Ophthalmology, 2014
First described more than a century ago, Fuchs endothelial corneal dystrophy (FECD) is a common disease characterized by progressive loss of endothelial cells, thickening of the Descemet membrane, and deposition of extracellular matrix in the form of guttae.
Angela Y, Zhu, Charles G, Eberhart, Albert S, Jun   +2 more
openaire   +2 more sources

PEDF Prevents Corneal Endothelial Dysfunction of Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
The purpose of this study was to explore the protection of pigment epithelium-derived factor (PEDF) on the corneal endothelium in Fuchs endothelial corneal dystrophy (FECD).PEDF levels in aqueous humor of FECD patients were quantified by enzyme-linked immunosorbent assay.
Yao S, Qiao Y, Lin Y, Sui X, Zhou Q, Wang T, Wang Q, Zhao C.   +7 more
europepmc   +4 more sources

Fuchs endothelial corneal dystrophy and keratoconus: A very rare coincidence [PDF]

, 2023
It was aimed to represent a case with concurrent Fuchs endothelial corneal dystrophy (FECD) and keratoconus (KC) as a rare entity. A 35-year-old woman had a best-corrected visual acuity was 20/20 in the right eye and 20/60 in the left eye (Snellen ...
Ibrahim Toprak, Deniz Kılıç, Emre Güneş   +2 more
core   +2 more sources

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats. [PDF]

J Pathol
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM ...
Vaitinadapoulé H, Onitiu D, Maurin C, Travers G, Crouzet E, Dorado-Cortez O, Poinard S, He Z, Forest F, Ollier E, Touraine R, Gain P, Perone JM, Thuret G, French Fuchs Study Group (FFSG).   +14 more
europepmc   +2 more sources

Fuchs’ endothelial corneal dystrophy RNA sequencing datasets for meta-analysis.

, 2023
Fuchs’ endothelial corneal dystrophy RNA sequencing datasets for meta-analysis.
V. Vinod Mootha (6264278), Ashwani Kumar (55732), Xunzhi Zhang (14631644), Adwait A. Sathe (6541643), Chao Xing (28961)   +4 more
core   +1 more source

Additional file 2 of A 20-year bibliometric analysis of Fuchs endothelial corneal dystrophy: from 2001 to 2020

, 2022
Additional file 2: Supplementary Figure 1. Contributions of different countries to FECD research.
Yuliang Wang (437561), Luoli Zhang (12841826), Yimin Wang (724389), Feng Lin (23861), Xingtao Zhou (441471), Dan Fu (1323018)   +5 more
core   +1 more source

Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy [PDF]

Seminars in Ophthalmology, 2019
Fuchs endothelial corneal dystrophy (FECD) is characterized by the progressive degeneration of the corneal endothelium (CE). The purpose of this article is to review the diagnostic tools available to image and assess the CE in FECD. Slit-lamp biomicroscopy with specular reflection and retroillumination are important techniques to assess the CE ...
Stephan Ong Tone, Ula Jurkunas
openaire   +2 more sources

Fuchs' Endothelial and Myotonic Dystrophies: Corneal Dystrophy in Myotonic Patients [PDF]

Investigative Opthalmology & Visual Science, 2017
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De Bernardo, Maddalena, Rosa, Nicola
openaire   +3 more sources