Results 71 to 80 of about 8,688 (228)

Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis

open access: yesProgress in Retinal and Eye Research, 2021
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal endothelial dystrophy and the leading indication for corneal transplantation worldwide. FECD is characterized by the progressive decline of corneal endothelial cells (CECs) and the formation of extracellular matrix (ECM) excrescences in Descemet's membrane (DM), called guttae,
Stephan Ong Tone   +5 more
openaire   +3 more sources

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

open access: yesAdvanced Therapeutics, Volume 8, Issue 9, September 2025.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Cataract surgery in patients with Fuchs’ endothelial corneal dystrophy

open access: yesCommunity Eye Health Journal, 2019
Cataract surgery risks corneal decompensation in patients with Fuchs’ endothelial corneal dystrophy, but it can also be combined with endothelial keratoplasty to address the condition.
Soujanya Kaup, Suresh K Pandey
doaj  

Secondary sulcus IOL implantation for presbyopia correction following Descemet Membrane Endothelial Keratoplasty

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: Report a case where the patient desired spectacle independence after phacoemulsification and Descemet membrane endothelial keratoplasty (DMEK) due to Fuchs’ endothelial dystrophy.
Luiza Moschetta Zimmermann   +4 more
doaj   +1 more source

Long-term results of corneal wedge resections for the correction of high astigmatism [PDF]

open access: yes, 1990
We retrospectively evaluated 41 corneal wedge resections, performed for the correction of high astigmatism in 40 patients who were spectacle and contact lens intolerant. Keratometric astigmatism decreased from an average of 11.7 diopters (range 5 to 22.5
Beekhuis, W.H. (Houdijn)   +4 more
core   +1 more source

Normative Values on Stromal Curvature, Power and Corneal‐Stromal Curvature Ratios From a Hybrid AS‐OCT

open access: yesClinical &Experimental Ophthalmology, Volume 53, Issue 7, Page 746-755, September/October 2025.
ABSTRACT Background To establish normative values for stromal curvature and its relationships to anterior and posterior curvature. Methods Retrospective observational study. Data were obtained from 75 eyes of cataract surgery patients using a high‐resolution anterior segment optical coherence tomograph (AS‐OCT; MS‐39, CSO).
Jascha A. Wendelstein   +7 more
wiley   +1 more source

Retained Descemet’s membrane following penetrating keratoplasty for Fuchs’ endothelial dystrophy: a case report of a post-operative complication

open access: yesClinical Ophthalmology, 2013
Katherine McVeigh,1,3,* Kurt Spiteri Cornish,3 Aravind R Reddy,3 Georgios Vakros2,3,* 1Eye Clinic, Royal United Bath Hospital, Bath, UK; 2Birmingham Midland Eye Centre, Birmingham City Hospital, Birmingham, UK; 3Ophthalmology Department, Aberdeen Royal ...
McVeigh K   +3 more
doaj  

Ciliochoroidal detachment following pure sulfur hexafluoride injection in Descemet stripping automated endothelial keratoplasty [PDF]

open access: yes, 2017
Received 29 October 2016, Accepted 6 March 2017, Available online 20 April 2017Unidad Docente de Inmunología, Oftalmología y ORLFac.
Benítez del Castillo, José Manuel   +4 more
core   +1 more source

Anterior Keratocyte Depletion in Fuchs Endothelial Dystrophy [PDF]

open access: yesArchives of Ophthalmology, 2011
To determine if keratocyte populations are different in corneas with Fuchs dystrophy compared with control corneas.Eleven corneas excised during penetrating keratoplasty for Fuchs dystrophy and 5 control corneas of eyes enucleated for choroidal melanoma were examined using light microscopy.
Laura A, Hecker   +3 more
openaire   +2 more sources

Biocompatibility of Genetically‐Engineered Pig Cornea in Corneal Xenotransplantation: Preliminary In Vitro Study

open access: yesXenotransplantation, Volume 32, Issue 5, September/October 2025.
ABSTRACT Introduction We aimed to evaluate biophysical compatibility of corneal endothelial cells in genetically‐engineered (GE) pigs to identify the best candidate for in vivo nonhuman primate (NHP) study and to collect baseline data for future clinical trials from a biological function perspective.
Seung Hyeun Lee   +8 more
wiley   +1 more source

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