Results 11 to 20 of about 3,422 (115)

Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy

Ophthalmology Science, 2021
Purpose: To investigate if corneal endothelial cells (CECs) in Fuchs endothelial corneal dystrophy (FECD) have altered cellular migration compared with normal controls. Design: Comparative analysis.
Stephan Ong Tone, MDCM, PhD, Adam Wylegala, MD, Myriam Böhm, MD, Geetha Melangath, PhD, Neha Deshpande, MSc, Ula V. Jurkunas, MD   +5 more
doaj   +1 more source

Transient peripheral edema following displaced corneal graft after descemet stripping automated endothelial keratoplasty (DSAEK): case presentation

BMC Ophthalmology, 2011
Background Descemet's Stripping with Automated Endothelial Keratoplasty (DSAEK) is constantly gaining popularity in the management of endothelial dysfunctions such as bullous keratopathy or Fuchs' dystrophy.
Kymionis George D, Portaliou Dimitra M, Ide Takeshi, Yoo Sonia H   +3 more
doaj   +1 more source

Outcome of Two Corneal Collagen Crosslinking Methods in Bullous Keratopathy due to Fuchs’ Endothelial Dystrophy

Case Reports in Medicine, 2014
Four eyes of 2 patients with corneal edema due to Fuchs’ endothelial dystrophy were treated with CXL using the standard protocol. Since no improvement in visual acuity, corneal clarity, thickness, or pain sensation was evident in any eye at month 12, 2 ...
Omur O. Ucakhan, Ayhan Saglik
doaj   +1 more source

Cataract surgery in patients with Fuchs’ dystrophy and corneal decompensation indicated for Descemet's membrane endothelial keratoplasty

Scientific Reports, 2022
The availability of corneal donor tissue is limited in most developing countries. This study evaluated whether patients with coexisting cataract and Fuchs’ dystrophy with corneal decompensation awaiting Descemet’s membrane endothelial keratoplasty (DMEK)
Wei-Yi Chou, Yih-Shiuan Kuo, Pei-Yu Lin
doaj   +1 more source

Expression and Function of ZEB1 in the Cornea

Cells, 2021
ZEB1 is an important transcription factor for epithelial to mesenchymal transition (EMT) and in the regulation of cell differentiation and transformation.
Yingnan Zhang, Xiao Liu, Wei Liang, Douglas C. Dean, Lijun Zhang, Yongqing Liu   +5 more
doaj   +1 more source

Dataset on transcriptome profiling of corneal endothelium from patients with Fuchs endothelial corneal dystrophy

Data in Brief, 2019
Fuchs endothelial corneal dystrophy (FECD) is a bilateral inherited eye disease with advanced forms only treatable by corneal transplantation. The pathogenesis of FECD has not been worked out yet, however, trinucleotide repeat polymorphism CTG18.1 in the
Anastasia S. Nikitina, Alexandra V. Belodedova, Boris E. Malyugin, Elena I. Sharova, Elena S. Kostryukova, Andrey K. Larin, Vladimir A. Veselovsky, Olga P. Antonova, Liubov O. Skorodumova   +8 more
doaj   +1 more source

Corneal clearance and central endothelial cell repopulation despite graft detachment after Descemet membrane endothelial keratoplasty

GMS Ophthalmology Cases, 2019
Objective: Descemet membrane endothelial keratoplasty (DMEK) is the gold standard procedure for treatment of primary corneal endothelial disorders. Graft detachment is a frequent complication of DMEK, which often requires re-operation or re-bubbling ...
Daravagka, Maria, Nestler, Andrei, Wiedemann, Peter, Girbardt, Christian   +3 more
doaj   +1 more source

Phototherapeutic keratectomy for anterior stromal fibrosis following DMEK

American Journal of Ophthalmology Case Reports, 2020
Purpose: Anterior stromal fibrosis is often seen in advanced cases of Fuchs endothelial dystrophy or secondary endothelial insufficiency. As Descemet membrane endothelial keratoplasty (DMEK) can completely eliminate the corneal edema and the guttae in ...
Philip Maier, Thomas Reinhard
doaj   +1 more source

Regenerative medicine in Fuchs' endothelial corneal dystrophy

Taiwan Journal of Ophthalmology, 2021
The management of Fuchs' endothelial corneal dystrophy (FECD) has evolved rapidly since the introduction of endothelial keratoplasty (EK). In recent years, advances in our understanding of endothelial cell biology, in particular with respect to the ...
Amy E Yuan, Roberto Pineda
doaj   +1 more source

SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress

Scientific Reports, 2017
Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha, Sunita Chaurasia, Charanya Ramachandran, Sanhita Roy   +3 more
doaj   +1 more source