Results 21 to 30 of about 6,377 (178)
Scientific Reports, 2022 The availability of corneal donor tissue is limited in most developing countries. This study evaluated whether patients with coexisting cataract and Fuchs’ dystrophy with corneal decompensation awaiting Descemet’s membrane endothelial keratoplasty (DMEK)
Wei-Yi Chou, Yih-Shiuan Kuo, Pei-Yu Lin
doaj +1 more source
Expression and Function of ZEB1 in the Cornea
Cells, 2021 ZEB1 is an important transcription factor for epithelial to mesenchymal transition (EMT) and in the regulation of cell differentiation and transformation.
Yingnan Zhang +5 more
doaj +1 more source
Primary graft failure associated with epithelial downgrowth: a case report [PDF]
, 2005 Background Epithelial downgrowth is a rare complication of ocular surgery. While the features of epithelial downgrowth following corneal transplantation are well described, its association with primary graft failure has only been reported once previously.
Anthony J Aldave +27 more
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Data in Brief, 2019 Fuchs endothelial corneal dystrophy (FECD) is a bilateral inherited eye disease with advanced forms only treatable by corneal transplantation. The pathogenesis of FECD has not been worked out yet, however, trinucleotide repeat polymorphism CTG18.1 in the
Anastasia S. Nikitina +8 more
doaj +1 more source
Role of the TCF4 gene intronic variant in normal variation of corneal endothelium [PDF]
, 2012 PURPOSE: To identify early features of Fuchs endothelial dystrophy (FED) in carriers of the rs613872(G) transcription factor 4 gene (TCF4) aged 20 to 21 years.
Crawford, Geoffrey J. +8 more
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A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. [PDF]
, 2017 Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci have been reported, accounting for 1.5% of IOP variability.
Banda, Yambazi +10 more
core +3 more sources
Multimodal Highlighting of Structural Abnormalities in Diabetic Rat and Human Corneas. [PDF]
, 2013 PURPOSE: This study aimed to highlight structural corneal changes in a model of type 2 diabetes, using in vivo corneal confocal microscopy (CCM). The abnormalities were also characterized by transmission electron microscopy (TEM) and second harmonic ...
Behar-Cohen, F. +7 more
core +5 more sources
GMS Ophthalmology Cases, 2019 Objective: Descemet membrane endothelial keratoplasty (DMEK) is the gold standard procedure for treatment of primary corneal endothelial disorders. Graft detachment is a frequent complication of DMEK, which often requires re-operation or re-bubbling ...
Daravagka, Maria +3 more
doaj +1 more source
Phototherapeutic keratectomy for anterior stromal fibrosis following DMEK
American Journal of Ophthalmology Case Reports, 2020 Purpose: Anterior stromal fibrosis is often seen in advanced cases of Fuchs endothelial dystrophy or secondary endothelial insufficiency. As Descemet membrane endothelial keratoplasty (DMEK) can completely eliminate the corneal edema and the guttae in ...
Philip Maier, Thomas Reinhard
doaj +1 more source
Rho-associated kinase inhibitor eye drop (Ripasudil) transiently alters the morphology of corneal endothelial cells [PDF]
, 2015 PURPOSE: Ripasudil (Glanatec), a selective Rho-associated coiled coil-containing protein kinase (ROCK) inhibitor, was approved in Japan in September 2014 for the treatment of glaucoma and ocular hypertension.
Fullwood, Nigel J. +6 more
core +1 more source