Results 11 to 20 of about 609,006 (169)

Rho-Kinase Inhibitors in the Management of Fuchs Endothelial Corneal Dystrophy: A Review [PDF]

Medicina
Fuchs endothelial corneal dystrophy (FECD) is the most common corneal endothelial dystrophy. It is characterized by the progressive loss of corneal endothelial cells (CECs), guttae formation on the Descemet membrane, and corneal edema, leading to visual ...
Anđela Jukić, Ana Pupić Bakrač, Biljana Đapic Ivančić, Andrijana Kopić, Ana Meter, Rajka Kasalica Žužul, Josip Pavan, Tomislav Jukić   +7 more
doaj   +3 more sources

Regenerative medicine in Fuchs' endothelial corneal dystrophy

Taiwan Journal of Ophthalmology, 2021
The management of Fuchs' endothelial corneal dystrophy (FECD) has evolved rapidly since the introduction of endothelial keratoplasty (EK). In recent years, advances in our understanding of endothelial cell biology, in particular with respect to the ...
Amy E Yuan, Roberto Pineda
doaj   +2 more sources

Exploring the histopathological signature of repeat-mediated Fuchs endothelial corneal dystrophy. [PDF]

Acta Ophthalmol
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Kladny AS, Bhattacharyya N, Abreu Costa M, Tuft SJ, Thaung C, Davidson AE.   +5 more
europepmc   +2 more sources

Fuchs endothelial corneal dystrophy: current perspectives

Clinical Ophthalmology, 2016
Gustavo Vedana, Guadalupe Villarreal Jr, Albert S Jun Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA Abstract: Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in ...
Vedana G, Villarreal Jr G, Jun AS
doaj   +1 more source

Cataract surgery in patients with Fuchs’ endothelial corneal dystrophy [PDF]

Community Eye Health Journal, 2019
Cataract surgery risks corneal decompensation in patients with Fuchs’ endothelial corneal dystrophy, but it can also be combined with endothelial keratoplasty to address the condition.
Soujanya Kaup, Suresh K Pandey
doaj   +1 more source

Comparative analysis of ultrasound and femtolaser-assisted phacoemulsification in patients with primary endothelial Fuchs corneal dystrophy

Офтальмохирургия, 2021
Purpose. To highlight the comparative results of surgical treatment of patients with primary Fuchs’ endothelial corneal dystrophy (FECD) using the methods of classical ultrasonic phacoemulsification and femtolaser-assisted phacoemulsification of cataract.
B. E. Malyugin, O. P. Antonova, G. A. Umbetalieva, Z. R. Ebzeeva   +3 more
doaj   +2 more sources

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats. [PDF]

J Pathol
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM ...
Vaitinadapoulé H, Onitiu D, Maurin C, Travers G, Crouzet E, Dorado-Cortez O, Poinard S, He Z, Forest F, Ollier E, Touraine R, Gain P, Perone JM, Thuret G, French Fuchs Study Group (FFSG).   +14 more
europepmc   +2 more sources

Corneal clearance and central endothelial cell repopulation despite graft detachment after Descemet membrane endothelial keratoplasty

GMS Ophthalmology Cases, 2019
Objective: Descemet membrane endothelial keratoplasty (DMEK) is the gold standard procedure for treatment of primary corneal endothelial disorders. Graft detachment is a frequent complication of DMEK, which often requires re-operation or re-bubbling ...
Daravagka, Maria, Nestler, Andrei, Wiedemann, Peter, Girbardt, Christian   +3 more
doaj   +2 more sources

Review of the Literature: Surgery Indications for Fuchs' Endothelial Corneal Dystrophy. [PDF]

J Clin Med
Objectives: To provide an overview of the preoperative indications for endothelial graft in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: A comprehensive database search without date restrictions was performed in PubMed.
Tourabaly M, Knoeri J, Georgeon C, Borderie V.   +3 more
europepmc   +2 more sources

Preclinical Models for Studying Fuchs Endothelial Corneal Dystrophy. [PDF]

Cells
Fuchs Endothelial Corneal Dystrophy (FECD) is a corneal endothelial disease that causes microenvironment alterations and endothelial cell loss, which leads to vision impairment. It has a high global prevalence, especially in elderly populations.
Sun F, Xi LWQ, Luu W, Enkhbat M, Neo D, Mehta JS, Peh GSL, Yim EKF.   +7 more
europepmc   +2 more sources