Exploring the histopathological signature of repeat-mediated Fuchs endothelial corneal dystrophy. [PDF]
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Kladny AS +5 more
europepmc +2 more sources
Application of convolutional neural networks to define Fuchs endothelial dystrophy
Purpose. To evaluate the application of convolutional neural networks for the automatic detection of Fuchs’ dystrophy. Material and methods. The study included 700 biomicroscopic images of the corneal endothelium (Tomey EM-3000) randomly selected from ...
S.V. Shukhaev +3 more
doaj +1 more source
Diagnosis and management of iridocorneal endothelial syndrome [PDF]
The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella +5 more
core +2 more sources
The article discusses the effectiveness of accelerated collagen crosslinking in the treatment of patients with corneal diseases, a common basic pathogenetic link of which is endothelial corneal decompensation.
S. Yu. Astakhov +3 more
doaj +1 more source
Descemet stripping automated endothelial keratoplasty in Fuchs' corneal endothelial dystrophy: Anterior segment optical coherence tomography and in vivo confocal microscopy analysis [PDF]
Background: To evaluate the in vivo corneal changes using in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (
Busin, Massimo +4 more
core +1 more source
Increased Corneal Endothelial Cell Migration in Fuchs Endothelial Corneal Dystrophy
Purpose: To investigate if corneal endothelial cells (CECs) in Fuchs endothelial corneal dystrophy (FECD) have altered cellular migration compared with normal controls. Design: Comparative analysis.
Stephan Ong Tone, MDCM, PhD +5 more
doaj +1 more source
Congenital hereditary endothelial dystrophy with progressive sensorineural deafness (Harboyan syndrome) [PDF]
Harboyan syndrome is a degenerative corneal disorder defined as congenital hereditary endothelial dystrophy (CHED) accompanied by progressive, postlingual sensorineural hearing loss.
Julie Desir, Marc Abramowicz
core +1 more source
Screening of the COL8A2 gene in an Australian family with early-onset Fuchs’ endothelial corneal dystrophy [PDF]
This item is under embargo for a period of 12 months from the date of publication, in accordance with the publisher's ...
Burdon, Kathryn Penelope +4 more
core +1 more source
Femtosecond laser and microkeratome-assisted Descemet stripping endothelial keratoplasty: first clinical results [PDF]
Purpose: To evaluate the use of a femtosecond laser combined with a microkeratome in the preparation of posterior corneal disks for Descemet stripping automated endothelial keratoplasty (DSAEK).
Costa, E +5 more
core +1 more source
Four eyes of 2 patients with corneal edema due to Fuchs’ endothelial dystrophy were treated with CXL using the standard protocol. Since no improvement in visual acuity, corneal clarity, thickness, or pain sensation was evident in any eye at month 12, 2 ...
Omur O. Ucakhan, Ayhan Saglik
doaj +1 more source

