Regenerative medicine in Fuchs' endothelial corneal dystrophy
The management of Fuchs' endothelial corneal dystrophy (FECD) has evolved rapidly since the introduction of endothelial keratoplasty (EK). In recent years, advances in our understanding of endothelial cell biology, in particular with respect to the ...
Amy E Yuan, Roberto Pineda
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Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. [PDF]
The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient ...
Aldave, Anthony J +14 more
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A comparison of endothelial and penetrating keratoplasty outcomes following failed penetrating keratoplasty: a registry study [PDF]
Author version made available in accordance with publisher copyright policy.Purpose To compare graft survival and visual outcomes for endothelial keratoplasty (EK) after a first penetrating keratoplasty (PK), with outcomes of repeat PK after a first ...
Australian Corneal Graft Registry, Contributors +5 more
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Cornea organoids from human induced pluripotent stem cells. [PDF]
The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M +5 more
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Assessment of endothelial cell density and corneal thickness in corneal grafts an average of 5 years after penetrating keratoplasty [PDF]
BACKGROUND Corneal transparency is a useful indicator for corneal function. Our aim was to investigate central corneal endothelial cells and corneal thickness in transplanted corneas at an average of 5.4 years after penetrating keratoplasty ...
Berta, András +4 more
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Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha +3 more
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Ciliochoroidal detachment following pure sulfur hexafluoride injection in Descemet stripping automated endothelial keratoplasty [PDF]
Received 29 October 2016, Accepted 6 March 2017, Available online 20 April 2017Unidad Docente de Inmunología, Oftalmología y ORLFac.
Benítez del Castillo, José Manuel +4 more
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Fuchs endothelial corneal dystrophy (FECD) is a bilateral dystrophy of the cornea and the most common indication for corneal transplantation procedures.
Ivan Merdžo +6 more
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Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy
Fuchs endothelial corneal dystrophy (FECD) is one of the most common reasons for corneal transplantation, and is known to cluster in families. Here, the authors discover new genetic loci associated with FECD with sex-specific effects and implications for
Natalie A. Afshari +35 more
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Endothelial dysfunction in a child with Pearson marrow-pancreas syndrome managed with Descemet stripping automated endothelial keratoplasty using a suture pull-through techniqu [PDF]
A 4-year-old girl with a history of Pearson marrow-pancreas syndrome presenting with severe, progressive photophobia was found to have bilateral, diffuse corneal thickening and peripheral pigmentary retinopathy. She underwent Descemet stripping automated
Areaux, Raymond G., Jr. +4 more
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