Results 61 to 70 of about 3,843 (175)

Tips, Tricks, and Guides in Descemet Membrane Endothelial Keratoplasty Learning Curve

Journal of Ophthalmology, 2021
Lamellar keratoplasty is fast becoming the most popular form of corneal transplantation. The adoption of Descemet membrane endothelial keratoplasty (DMEK) in the management of Fuchs endothelial dystrophy and pseudophakic bullous keratopathy is partly ...
Davide Borroni, Carlos Rocha de Lossada, Mohit Parekh, Kunal Gadhvi, Chiara Bonzano, Vito Romano, Hannah J. Levis, Aris Tzamalis, Bernhard Steger, Miguel Rechichi, Marina Rodriguez-Calvo-de-Mora   +10 more
doaj   +1 more source

Genetic Analysis of Pitt–Hopkins Syndrome Caused by a Novel Splicing Variant (c.1146+3A>T) in the TCF4 Gene

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
A novel pathogenic splicing variant (TCF4c.1146+3A>T) was identified in a fetus with increased nuchal translucency. The variant disrupts normal splicing, causing exon 14 skipping and protein truncation, which is consistent with Pitt–Hopkins Syndrome.
Wenlong Shen, Yan Zhang, Junjie Wu, Jue Zhao, Yaer Lv, Xiaohua Tang   +5 more
wiley   +1 more source

Phacoemulsification and Descemet's membrane endothelial keratoplasty in the presence of a corneal scar.

Vision Pan-America, 2015
To report the surgical outcome and visual rehabilitation  of a patient with Fuchs' dystrophy diagnosed with endothelial dysfunction associated with subepithelial and deep corneal scar and advanced cataract, treated with DMEK combined with ...
Nicolas Cesario Pereira, Aline Moiyama, Isabel Camila Amorim Gonzaga, Adriana dos Santos Forseto   +3 more
doaj   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs

Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Objective To compare unsedated noncontact specular microscopy imaging techniques for the canine corneal endothelium and identify the most effective technique. Animals Studied Nineteen eyes of 10 systemically healthy, staff‐owned dogs with clinically normal corneas were studied.
Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo   +4 more
wiley   +1 more source

Corneal endothelial cell dysfunction: etiologies and management

Therapeutic Advances in Ophthalmology, 2018
A transparent cornea is essential for the formation of a clear image on the retina. The human cornea is arranged into well-organized layers, and each layer plays a significant role in maintaining the transparency and viability of the tissue.
Sepehr Feizi
doaj   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

Corneal amyloid staining after trypan blue in Descemet's membrane endothelial keratoplasty

American Journal of Ophthalmology Case Reports
Purpose: This case report seeks to highlight impressive photographs of amyloid staining with trypan blue that persisted after DMEK surgery with 3 years follow-up. This has only been reported in the literature twice previously, and may have contributed to
Alexandra Klejn, Robin G. Abell
doaj   +1 more source

Cornea stress test--evaluation of corneal endothelial function in vivo by contact lens induced stress

Indian Journal of Ophthalmology, 1997
Reliable and valid assessment of corneal endothelial function is a critical input for diagnosing, prognosticating and monitoring progression of disorders affecting corneal endothelium. In 123 eyes, corneal endothelial function was assessed employing data
Saini Jagjit, Mittal Sangeet, Anand Mrinal   +2 more
doaj  

Distribution and Surgical Treatment of Corneal Dystrophies Over Eight Decades (1945–2024): An Analysis of Histopathologically Confirmed Cases from a German Center

Journal of Epidemiology and Global Health
Background Corneal dystrophies are inherited disorders that can lead to significant visual impairment and often require surgical intervention in advanced stages.
Othmane Touirssa, Philip Maier, Daniel Boehringer, Claudia Auw-Haedrich, Mateusz Glegola, Thomas Reinhard, Simone Nuessle   +6 more
doaj   +1 more source