Results 61 to 70 of about 6,427 (219)

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Update on the genetics of corneal endothelial dystrophies

Indian Journal of Ophthalmology, 2022
Corneal endothelial dystrophies are a heterogeneous group of diseases with different modes of inheritance and genetic basis for each dystrophy. The genes associated with these diseases encode transcription factors, structural components of the stroma and
Chitra Kannabiran, Sunita Chaurasia, Muralidhar Ramappa, Venkateswara Vinod Mootha   +3 more
doaj   +1 more source

Deformation velocity imaging using optical coherence tomography and its applications to the cornea [PDF]

, 2017
Optical coherence tomography (OCT) can monitor human donor corneas non-invasively during the de-swelling process following storage for corneal transplantation, but currently only resultant thickness as a function of time is extracted.
Dong, Y, Harding, SP, Kaye, SB, Lawman, S, Madden, PW, Mason, S, Romano, V, Shen, Y, Williams, BM, Willoughby, CE, Zheng, Y   +10 more
core   +1 more source

Pathological classification of Fuchs endothelial corneal dystrophy into several types and their relationships with CTG18.1 expansion repeats

The Journal of Pathology, Volume 269, Issue 2, Page 182-196, June 2026.
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is the most common primary disease of the corneal endothelium and the leading indication for corneal transplantation in Western countries. It is characterized by progressive accumulation, over two to three decades, of extracellular matrix (ECM) components in Descemet's membrane (DM ...
Hanielle Vaitinadapoulé, Daria Onitiu, Corantin Maurin, Gauthier Travers, Emmanuel Crouzet, Oliver Dorado‐Cortez, Sylvain Poinard, Zhiguo He, Fabien Forest, Edouard Ollier, Renaud Touraine, Philippe Gain, Jean‐Marc Perone, Gilles Thuret, the French Fuchs Study Group (FFSG), Diane Bernheim, Christophe Chiquet, Vincent Borderie, Tristan Bourcier, Jean‐Louis Bourges, Frédéric Chiambaretta, Béatrice Cochener, Louis Arnould, Florian Baudin, Catherine Creuzot, Vincent Daien, Alexandre Denoyer, Bernard Duchesne, Nicolas Duquesne, Pierre Fournie, Anne‐Sophie Gauthier, Philippe Gain, Gilles Thuret, Louis Hoffart, François Majo, Marc Muraine, Romain Mouchel, Jean Marc Perone, Jean Claude Quintyn, Alexandra Rabot, Alain Saad, Damien Gatinel, Pierre‐Yves Santiago, Jean‐Michel Bosc, David Touboul, Bertrand Vabres   +45 more
wiley   +1 more source

Late-onset Candida keratitis after Descemet stripping automated endothelial keratoplasty : clinical and confocal microscopic report [PDF]

, 2011
Purpose. To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). Methods.
Arance-Gil, Ángeles, González-Méijome, José Manuel, Gutiérrez, Ángel Ramón, Higueras-Esteban, Alejandro, Ortiz-Gomariz, Amanda, Villa-Collar, César   +5 more
core   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Comparison of corneal endothelial mosaic according to the age: the corimmo 3D project [PDF]

, 2016
International audienceAim: The human corneal endothelium is a monolayer of flat hexagonal cells. It is a nearly regular hexagonal tessellation during the first years of life, but with age, becomes less regular in shape and size.
crouzet, Emmanuel, Gain, Philippe, Gavet, Yann, Guerrero, Patricio, Pinoli, Jean-Charles, Rannou, Klervi, Ronin, Caroline, Thuret, Gilles   +7 more
core   +2 more sources

Comparison of Corneal Endothelial Imaging Techniques by Specular Microscopy in Unsedated Healthy Dogs

Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.
ABSTRACT Objective To compare unsedated noncontact specular microscopy imaging techniques for the canine corneal endothelium and identify the most effective technique. Animals Studied Nineteen eyes of 10 systemically healthy, staff‐owned dogs with clinically normal corneas were studied.
Hyunwoo Suk, Minju Kim, Dohyeong Kim, Seonmi Kang, Kangmoon Seo   +4 more
wiley   +1 more source

Axenfeld-Rieger anomaly and corneal endothelial dystrophy: a case series Anomalia de Axenfeld-Rieger e distrofia corneana endotelial: uma série de casos

Revista Brasileira de Oftalmologia, 2008
Report of a study of a family with a remarkable combination of endothelial corneal dystrophy, and anterior chamber dysgenesis classified as Axenfeld-Rieger anomaly. A 56 year-old female had blurred vision complaints.
Mariana Borges Oliveira, Roberto dos Santos Mitraud, Riuitiro Yamane   +2 more
doaj   +1 more source

Génexpresszió Fuchs-dystrophiában, pseudophakiás bullosus keratopathiában és keratoconusban = Gene expression in Fuchs' dystrophy, pseudophakic bullous keratopathy and keratoconus [PDF]

, 2009
A Fuchs dystrophia (dystrophia corneae endo-, epithelialis) és a pseudophakiás bullosus keratopathia a hasonló klinikai képet mutat, mindkettő alapja a cornea endothelsejtjeinek degenerációja.
Szentmáry, Nóra, Süveges, Ildikó
core