Results 71 to 80 of about 3,843 (175)

Clinical and genetic investigation of amantadine-associated corneal edema

Clinical Ophthalmology, 2018
Michelle M Hessen, Sina Vahedi, Chloe T Khoo, Gelareh Vakili, Allen O Eghrari Division of Cornea, Cataract, & External Diseases, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Purpose: Amantadine use
Hessen MM, Vahedi S, Khoo CT, Vakili G, Eghrari AO   +4 more
doaj  

Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy

Biology
The Klotho loss-of-function mutation is known to cause accelerated senescence in many organs, but its effects on the cornea have not been published. The present study aims to investigate the effects of the Klotho null mutation on cornea degeneration and ...
Chun-Yen Wu, Da-Fong Song, Zhi-Jia Chen, Chao-Sheng Hu, David Pei-Cheng Lin, Han-Hsin Chang   +5 more
doaj   +1 more source

Toric IOL in Combined DMEK and Cataract Surgery

Clinical Ophthalmology, 2021
Bruno Lovaglio Cancado Trindade,1– 3 Julia Costa Garcia,2 Laila Rahme Nogueira2 1Cançado Trindade Eye Institute, Belo Horizonte, Brazil; 2Medical Science School of Medicine - FELUMA, Belo Horizonte, Brazil; 3Cornea Department, Medical ...
Trindade BLC, Garcia JC, Nogueira LR
doaj  

Preclinical Models for Studying Fuchs Endothelial Corneal Dystrophy. [PDF]

Cells
Fuchs Endothelial Corneal Dystrophy (FECD) is a corneal endothelial disease that causes microenvironment alterations and endothelial cell loss, which leads to vision impairment. It has a high global prevalence, especially in elderly populations. FECD is also one of the leading indications of corneal transplantation globally.
Sun F, Xi LWQ, Luu W, Enkhbat M, Neo D, Mehta JS, Peh GSL, Yim EKF.   +7 more
europepmc   +4 more sources

Secondary sulcus IOL implantation for presbyopia correction following Descemet Membrane Endothelial Keratoplasty

American Journal of Ophthalmology Case Reports
Purpose: Report a case where the patient desired spectacle independence after phacoemulsification and Descemet membrane endothelial keratoplasty (DMEK) due to Fuchs’ endothelial dystrophy.
Luiza Moschetta Zimmermann, Guilherme Vieira Peixoto, Júlia Margoni Biluca, José Maurílio Tavares de Lucena, Ricardo Menon Nosé   +4 more
doaj   +1 more source

Evaluation of endothelial/Descemet membrane complex of eye bank donor corneas using enhanced depth imaging optical coherence tomography

Clinical Ophthalmology, 2019
Zeba A Syed,1 Gustavo Rosa Gameiro,1 Marco Ruggeri,1 Amr Elsawy,1,2 Ibrahim Sayed-Ahmed,1 Vatookarn Roongpoovapatr,1 Mohamed Abdel-Mottaleb,2 Mohamed Abou Shousha11Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller ...
Syed ZA, Gameiro GR, Ruggeri M, Elsawy A, Sayed-Ahmed I, Roongpoovapatr V, Abdel-Mottaleb M, Abou Shousha M   +7 more
doaj  

Mutagenesis of mitochondrial DNA in Fuchs endothelial corneal dystrophy

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2014
Fuchs endothelial corneal dystrophy (FECD) is an age-related, slowly progressive disease, which may lead to loss of vision resulting from apoptosis of corneal endothelial (CE) cells, dysfunction of Descemet membrane (DM) and corneal edema. A growing body of evidence suggests that oxidative stress may play a major role in the pathogenesis of FECD and ...
Czarny, P, Seda, A, Wielgorski, M, Binczyk, E, Markiewicz, B, Kasprzak, E, Jimenez-Garcia, Manuel Pedro, Grabska-Liberek, I, Pawlowska, E, Blasiak, Janusz, Szaflik, J, Szaflik, JP   +11 more
openaire   +3 more sources

Regulation of Oxidative Stress in Corneal Endothelial Cells by Prdx6

Antioxidants, 2018
The inner layer of the cornea, the corneal endothelium, is post-mitotic and unable to regenerate if damaged. The corneal endothelium is one of the most transplanted tissues in the body.
Matthew Lovatt, Khadijah Adnan, Gary S. L. Peh, Jodhbir S. Mehta   +3 more
doaj   +1 more source

Fenofibrate in ophthalmology: therapeutic efficacy and mechanisms

Journal of Pharmacy & Pharmaceutical Sciences
Ophthalmic diseases are a growing global cause of visual impairment, driven by population aging and the rising prevalence of diabetes mellitus. Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist widely used for dyslipidemia ...
Sean Chung-Hei Ho, Isabelle Xin Yu Lee, Chang Liu, Mingyi Yu, Hong Chang Tan, Gavin Siew Wei Tan, Yu-Chi Liu, Yu-Chi Liu   +7 more
doaj   +1 more source

Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae

Clinical Ophthalmology, 2020
Bu Ki Kim,1 Young Taek Chung2 1Onnuri Smile Eye Clinic, Gangnam-Daero 65 Gil, Seoul, Seocho-gu, Republic of Korea; 2Onnuri Eye Hospital, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaCorrespondence: Young Taek Chung 325, Baekje-Daero,
Kim BK, Chung YT
doaj