Results 71 to 80 of about 6,427 (219)
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan +9 more
wiley +1 more source
Automated detection and classification of nuclei in immunohistochemical stainings for Fuchs' endothelial corneal dystrophy [PDF]
Fuchs’ endothelial corneal dystrophy (FECD) is a degenerative disease that affects the elderly population, and which lacks a unifying pathogenic theory and tangible drug targets.
Janssens, Thomas +5 more
core +2 more sources
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye +10 more
wiley +1 more source
Evolving Techniques and Indications of Descemet Membrane Endothelial Keratoplasty
Endothelial keratoplasty has replaced traditional penetrating keratoplasty for the treatment of corneal endothelial dysfunction. It offers faster, more predictable, stable visual recovery and low rejection rates while the surgery itself is less invasive.
Özlem Evren Kemer +3 more
doaj +1 more source
The Australian Corneal Graft Registry 2007 Report [PDF]
The Australian Corneal Graft Registry opened in May 1985 and thus has now been in operation for over 22 years. The census date for this report was 01/09/2006. Over the years, we have collected data on more than 18,500 corneal grafts.
Bartlett, Christine Mary +4 more
core
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Fuchs endothelial corneal dystrophy and small eyes
Aim: To determine whether there is an association between Fuchs endothelial corneal dystrophy (FECD) and shorter axial length (AL), shallower anterior chamber depth (ACD) and higher spherical equivalent (SE). In addition, to evaluate whether there is a correlation between AL and severity of corneal decompensation in FECD, using corneal thickness as a ...
John Males, Nicole Shao-Yuen Lim
openaire +2 more sources
Katherine McVeigh,1,3,* Kurt Spiteri Cornish,3 Aravind R Reddy,3 Georgios Vakros2,3,* 1Eye Clinic, Royal United Bath Hospital, Bath, UK; 2Birmingham Midland Eye Centre, Birmingham City Hospital, Birmingham, UK; 3Ophthalmology Department, Aberdeen Royal ...
McVeigh K +3 more
doaj
Update on the Surgical Management of Fuchs Endothelial Corneal Dystrophy
Fuchs endothelial corneal dystrophy (FECD) is the most common posterior corneal dystrophy and the leading indication for corneal transplantation in the United States.
Andrea L. Blitzer, Kathryn A. Colby
doaj +1 more source
Tips, Tricks, and Guides in Descemet Membrane Endothelial Keratoplasty Learning Curve
Lamellar keratoplasty is fast becoming the most popular form of corneal transplantation. The adoption of Descemet membrane endothelial keratoplasty (DMEK) in the management of Fuchs endothelial dystrophy and pseudophakic bullous keratopathy is partly ...
Davide Borroni +10 more
doaj +1 more source

