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Computational insights into fucoidan–receptor binding: Implications for fucoidan-based targeted drug delivery

Drug Discovery Today
Fucoidan, a polysaccharide from seaweed, holds promise as a drug delivery system and immune modulator; however, its exact mechanism of action remains unclear. As various carbohydrates play key roles in immune responses by binding to carbohydrate-binding proteins like lectins, fucoidan is hypothesized to interact with immune receptors, potentially ...
Rumana, Ferdushi   +5 more
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Fucoidan in future applications – an industrial perspective

2020
Fucoidan is a sulphated biopolymer present in brown seaweeds and some other marine organisms. Current commercial fucoidan grades are derived from brown seaweeds, and their structure is dependent on seaweed source. The importance of structure will depend on type of application. With applications potentially[for full text, please go to the a.m. URL]
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Fucoidan

2022
Ellya Sinurat   +3 more
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[The anticoagulant activity of fucoidans].

Eksperimental'naia i klinicheskaia farmakologiia, 1997
The influence of the degree of fucoidan macromolecules sulfation on their ability to induce an anticoagulant effect was studied. In in vitro experiments with the basic stain and in in vivo experiments on rabbits with performance of Quick's test, APTT, and spectrophotometric determination of antithrombin III (AT-III) activity a direct dependence of the ...
E A, Gavrilova   +4 more
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Therapeutic potential of fucoidan in atherosclerosis: a review

Food & Function
Fucoidan from brown seaweed shows lipid-lowering, antioxidant, anti-inflammatory, endothelial-protective and prebiotic activities. These effects address key atherosclerosis mechanisms, making it a promising therapeutic candidate.
Qiujian Feng   +6 more
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Opportunities and challenges of fucoidan for tumors therapy

Carbohydrate Polymers
The large-scale collections, screening and discovery of biologically active and pharmacologically significant marine-derived natural products have garnered tremendous attraction. Edible brown algae are rich in fucoidan. Importantly, fucoidan has been reported to inhibit carcinogenesis and metastasis mainly through the regulation of deregulated cell ...
Haoyu, Yu   +6 more
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Structural diversity of fucoidans and their radioprotective effect

Carbohydrate Polymers, 2021
Tatiana N Zvyagintseva   +2 more
exaly  

The fate of fucoidan in the ocean

Rising carbon dioxide levels and the goals of the Paris Agreement have intensified the focus on carbon removal strategies. Blue carbon ecosystems, including mangroves, salt marshes, seagrass meadows and macroalgae are key to carbon sequestration due to their ability to store large amounts of carbon in their biomass.
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FUCOIDAN

1973
LANDIS W. DONER, ROY L. WHISTLER
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Fucoidans inhibited tau interaction and cellular uptake

Carbohydrate Polymers, 2023
Weihua Jin   +2 more
exaly  

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