Results 41 to 50 of about 5,635 (210)

Marine prebiotics mediate decolonization of Pseudomonas aeruginosa from gut by inhibiting secreted virulence factor interactions with mucins and enriching Bacteroides population

Journal of Biomedical Science, 2023
Background Pseudomonas aeruginosa intestinal carriage rates are significantly higher in immunosuppressed individuals and hospitalized patients who therefore have increased risk of infections and antibiotic-associated diarrhea.
Rajendra Prasad Janapatla, Anna Dudek, Chyi-Liang Chen, Chih-Hsien Chuang, Kun-Yi Chien, Ye Feng, Yuan-Ming Yeh, Yi-Hsin Wang, Hsin-Ju Chang, Yuan-Chuan Lee, Cheng-Hsun Chiu   +10 more
doaj   +1 more source

Research Progress on Chemical Degradation of Fucoidan for Preparation of Low-molecular Weight Fucoidan and Fucooligosaccharide

Shipin gongye ke-ji
Fucoidans are sulphated polysaccharides that are primarily derived from brown algae and marine invertebrates. Fucoidans generally have complex structural characteristics, which contribute to their various pharmacological activities including anti-tumor ...
Haidi LIU, Dongyue MA, Chenfeng JI, Guosong XIN, Wenlan LI, Shoudong GUO   +5 more
doaj   +1 more source

Influence of Fucoidan Extracts from Different Fucus Species on Adult Stem Cells and Molecular Mediators in In Vitro Models for Bone Formation and Vascularization

Marine Drugs, 2021
Fucoidans, sulfated polysaccharides extracted from brown algae, are marine products with the potential to modulate bone formation and vascularization processes.
Fanlu Wang, Yuejun Xiao, Sandesh Neupane, Signe Helle Ptak, Ramona Römer, Junyu Xiong, Julia Ohmes, Andreas Seekamp, Xavier Fretté, Susanne Alban, Sabine Fuchs   +10 more
doaj   +1 more source

Fucoidan Extracts Ameliorate Acute Colitis

PLOS ONE, 2015
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are an important cause of morbidity and impact significantly on quality of life. Overall, current treatments do not sustain a long-term clinical remission and are associated with adverse effects, which highlight the need for new treatment options.
Qi Ying Lean, Rajaraman D Eri, J Helen Fitton, Rahul P Patel, Nuri Gueven   +4 more
openaire   +4 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Identification of a Pro-Angiogenic Potential and Cellular Uptake Mechanism of a LMW Highly Sulfated Fraction of Fucoidan from Ascophyllum nodosum

Marine Drugs, 2016
Herein we investigate the structure/function relationships of fucoidans from Ascophyllum nodosum to analyze their pro-angiogenic effect and cellular uptake in native and glycosaminoglycan-free (GAG-free) human endothelial cells (HUVECs).
Nicolas Marinval, Pierre Saboural, Oualid Haddad, Murielle Maire, Kevin Bassand, Frederic Geinguenaud, Nadia Djaker, Khadija Ben Akrout, Marc Lamy de la Chapelle, Romain Robert, Olivier Oudar, Erwan Guyot, Christelle Laguillier-Morizot, Angela Sutton, Cedric Chauvierre, Frederic Chaubet, Nathalie Charnaux, Hanna Hlawaty   +17 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Cytotoxic Effects of Fucoidan Nanoparticles against Osteosarcoma [PDF]

Marine Drugs, 2013
In this study, we analyzed the size-dependent bioactivities of fucoidan by comparing the cytotoxic effects of native fucoidan and fucoidan lipid nanoparticles on osteosarcoma in vitro and in vivo. In vitro experiments indicated that nanoparticle fucoidan induced apoptosis of an osteosarcoma cell line more efficiently than native fucoidan.
Kimura, Ryuichiro, Rokkaku, Takayoshi, Takeda, Shinji, Senba, Masachika, Mori, Naoki   +4 more
openaire   +3 more sources

Fucoidans inhibit the formation of post-operative abdominal adhesions in a rat model. [PDF]

PLoS ONE, 2018
PURPOSE:Fibrin clot is essential for post-operative abdominal adhesion formation. Fucoidans, sulfated polysaccharides, inhibit fibrin clot formation.
Alex J Charboneau, John P Delaney, Greg Beilman   +2 more
doaj   +1 more source

Bioactivity of Fucoidan-Rich Extracts from Fucus vesiculosus against Rotavirus and Foodborne Pathogens

Marine Drugs, 2023
Marine algae are sources of bioactive components with defensive properties of great value against microbial infections. This study investigated the bioactivity of extracts from brown algae Fucus vesiculosus against rotavirus, the worldwide leading cause ...
Dimitra Graikini, Arturo B. Soro, Saravana P. Sivagnanam, Brijesh K. Tiwari, Lourdes Sánchez   +4 more
doaj   +1 more source