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Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
Angiogenesis and metastasis represent two challenging targets to combat cancer development in the later stages of its progression. Numerous studies have indicated the important role of natural products in blocking tumor angiogenesis signaling pathways in
Eleonora Turrini +2 more
doaj +1 more source
Fucoidan: Structure and Bioactivity [PDF]
Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed. For the past decade fucoidan has been extensively studied due to its numerous interesting biological activities. Recently the search for new drugs has raised interest in fucoidans.
Ruixiang Zhao, Xinjun Wei, Fei Lu, Bo Li
openaire +3 more sources
Fucoidans: a new frontier in brown seaweed research and biotechnology. [PDF]
Fucoidans, also known as fucose-containing sulfated polysaccharides (FCSPs), are abundant and structurally complex glycans found in the cell wall of brown algae.
Tonon T +3 more
europepmc +2 more sources
Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry [PDF]
Over the years, seaweeds have been highlighted as valuable natural sources of bioactive polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown seaweeds composed of a fucopyranose backbone and several monosaccharides, have been reported ...
Kanwugu, Osman Nabayire +15 more
core +1 more source
Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium [PDF]
Fucoidans from brown algae are described as anti-inflammatory, antioxidative, and antiangiogenic. We tested two Saccharina latissima fucoidans (SL-FRO and SL-NOR) regarding their potential biological effects against age-related macular degeneration (AMD).
Susanne Alban +15 more
core +1 more source
Fucoidans: Pro- or antiangiogenic agents? [PDF]
Sulfated polysaccharides of brown algae (fucoidans) attract great attention due to their high and strongly diversified biological activity. This review summarizes recent data on the structural variability of these polysaccharides and reports their anti- and proangiogenic properties.
Nadezhda E, Ustyuzhanina +5 more
openaire +2 more sources
Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study
Fucoidans are a class of fucose-rich sulfated polysaccharides derived from brown macroalgae that exert a range of biological activities in vitro and in vivo.
Nuri Gueven +6 more
doaj +1 more source
Perspectives for the Use of Fucoidans in Clinical Oncology
Fucoidans are natural sulfated polysaccharides that have a wide range of biological functions and are regarded as promising antitumor agents. The activity of various fucoidans and their derivatives has been demonstrated in vitro on tumor cells of ...
Mikhail V. Kiselevskiy +19 more
core +1 more source
Relevance of the Extraction Stage on the Anti-Inflammatory Action of Fucoidans [PDF]
The anti-inflammatory action of fucoidans is well known, based on both in vitro and some in vivo studies. The other biological properties of these compounds, their lack of toxicity, and the possibility of obtaining them from a widely distributed and ...
Rosa Meijide-Faílde +26 more
core +1 more source
Fucoidan has many biological functions, including anti-tumor activity. Additionally, it has been suggested that low-molecular-weight fucoidans have greater bioactivities.
Baozhen Luo +10 more
doaj +1 more source

