Ion-exchange purification and structural characterization of five sulfated fucoidans from brown algae [PDF]
, 2021 Fucoidans are a diverse class of sulfated polysaccharides integral to the cell wall of brown algae, and due to their various bioactivities, they are potential drugs. Standardized work with fucoidans is required for structure-function studies, but remains
Aachmann, Finn Lillelund +13 more
core +2 more sources
Fucoidan: Structure and Bioactivity [PDF]
Molecules, 2008 Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed. For the past decade fucoidan has been extensively studied due to its numerous interesting biological activities. Recently the search for new drugs has raised interest in fucoidans.
Ruixiang Zhao, Xinjun Wei, Fei Lu, Bo Li
openaire +3 more sources
Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
Marine Drugs, 2023 Angiogenesis and metastasis represent two challenging targets to combat cancer development in the later stages of its progression. Numerous studies have indicated the important role of natural products in blocking tumor angiogenesis signaling pathways in
Eleonora Turrini +2 more
doaj +1 more source
Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry [PDF]
, 2023 Over the years, seaweeds have been highlighted as valuable natural sources of bioactive polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown seaweeds composed of a fucopyranose backbone and several monosaccharides, have been reported ...
Kanwugu, Osman Nabayire +15 more
core +1 more source
Fucoidans: Pro- or antiangiogenic agents? [PDF]
Glycobiology, 2014 Sulfated polysaccharides of brown algae (fucoidans) attract great attention due to their high and strongly diversified biological activity. This review summarizes recent data on the structural variability of these polysaccharides and reports their anti- and proangiogenic properties.
Nadezhda E, Ustyuzhanina +5 more
openaire +2 more sources
Extraction of Fucoidan from Turbinaria decurrens and the Synthesis of Fucoidan-Coated AgNPs for Anticoagulant Application [PDF]
ACS Omega, 2021 Brown seaweeds usually contain alginate as a major polymer. The second major sulfated polymer in brown seaweeds is fucoidan, which has huge potential in medicinal applications. In this study, the photosynthetic pigments from Turbinaria decurrens were first extracted using chloroform/methanol in the ratio of 1:1 (v/v), followed by fucoidan extraction ...
Nagarajan Shanthi +4 more
openaire +3 more sources
Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study
Marine Drugs, 2020 Fucoidans are a class of fucose-rich sulfated polysaccharides derived from brown macroalgae that exert a range of biological activities in vitro and in vivo.
Nuri Gueven +6 more
doaj +1 more source
Antioxidants, 2021 Fucoidans exhibit a wide range of bioactivities and receive significant attention in functional food and cosmetic research. Industrial applications of fucoidan are limited partially due to high extraction and purification costs.
Ilekuttige Priyan Shanura Fernando +6 more
doaj +1 more source
Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium [PDF]
, 2023 Fucoidans from brown algae are described as anti-inflammatory, antioxidative, and antiangiogenic. We tested two Saccharina latissima fucoidans (SL-FRO and SL-NOR) regarding their potential biological effects against age-related macular degeneration (AMD).
Susanne Alban +15 more
core +1 more source
Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance
Marine Drugs, 2020 Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review
María Elena Reyes +5 more
doaj +1 more source