Results 31 to 40 of about 2,698 (202)

Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects

Marine Drugs, 2023
Angiogenesis and metastasis represent two challenging targets to combat cancer development in the later stages of its progression. Numerous studies have indicated the important role of natural products in blocking tumor angiogenesis signaling pathways in
Eleonora Turrini, Francesca Maffei, Carmela Fimognari   +2 more
doaj   +1 more source

Ion-exchange purification and structural characterization of five sulfated fucoidans from brown algae [PDF]

, 2021
Fucoidans are a diverse class of sulfated polysaccharides integral to the cell wall of brown algae, and due to their various bioactivities, they are potential drugs. Standardized work with fucoidans is required for structure-function studies, but remains
Aachmann, Finn Lillelund, Sichert, A., Hehemann, Jan-Hendrik, Rogniaux, Hélène, Rogniaux, H., Laillet, Brigitte, Klau, Leesa Jane, Klau, L., Laillet, B., Sichert, Andreas, Hehemann, J., Le Gall, S., Aachmann, F., Le Gall, Sophie   +13 more
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Marine fucoidans: Structural, extraction, biological activities and their applications in the food industry [PDF]

, 2023
Over the years, seaweeds have been highlighted as valuable natural sources of bioactive polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown seaweeds composed of a fucopyranose backbone and several monosaccharides, have been reported ...
Kanwugu, Osman Nabayire, Panda, P. K., Panda, Pritam Kumar,, Pritam Kumar Panda, Mensah, Emmanuel Ofosu, Mensah, E. O., Adadi, P., Adadi, Parise,, Kanwugu, O. N., Adadi, Parise, Panda, Pritam Kumar, Mensah, Emmanuel Ofosu,, Kanwugu, Osman Nabayire,, Parise Adadi, Emmanuel Ofosu Mensah, Osman Nabayire Kanwugu   +15 more
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Fucoidans: Pro- or antiangiogenic agents? [PDF]

Glycobiology, 2014
Sulfated polysaccharides of brown algae (fucoidans) attract great attention due to their high and strongly diversified biological activity. This review summarizes recent data on the structural variability of these polysaccharides and reports their anti- and proangiogenic properties.
Nadezhda E, Ustyuzhanina, Maria I, Bilan, Natalia A, Ushakova, Anatolii I, Usov, Mikhail V, Kiselevskiy, Nikolay E, Nifantiev   +5 more
openaire   +2 more sources

Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study

Marine Drugs, 2020
Fucoidans are a class of fucose-rich sulfated polysaccharides derived from brown macroalgae that exert a range of biological activities in vitro and in vivo.
Nuri Gueven, Kevin J. Spring, Sandra Holmes, Kiran Ahuja, Raj Eri, Ah Young Park, J Helen Fitton   +6 more
doaj   +1 more source

Fucoidan Fractionated from Sargassum coreanum via Step-Gradient Ethanol Precipitation Indicate Promising UVB-Protective Effects in Human Keratinocytes

Antioxidants, 2021
Fucoidans exhibit a wide range of bioactivities and receive significant attention in functional food and cosmetic research. Industrial applications of fucoidan are limited partially due to high extraction and purification costs.
Ilekuttige Priyan Shanura Fernando, Mawalle Kankanamge Hasitha Madhawa Dias, Dissanayaka Mudiyanselage Dinesh Madusanka, Eui Jeong Han, Min Ju Kim, Soo-Jin Heo, Ginnae Ahn   +6 more
doaj   +1 more source

Perspectives for the Use of Fucoidans in Clinical Oncology

, 2022
Fucoidans are natural sulfated polysaccharides that have a wide range of biological functions and are regarded as promising antitumor agents. The activity of various fucoidans and their derivatives has been demonstrated in vitro on tumor cells of ...
Mikhail V. Kiselevskiy, Kirgizov, Kirill I., Nadezhda E. Ustyuzhanina, Ustyuzhanina, Nadezhda E., Irina O. Chikileva, Kiselevskiy, Mikhail V., Tokatly, Alexandra I., Nifantiev, Nikolay E., Anisimova, Natalia Yu., Vinnitskiy, Dmitry Z., Alexandra I. Tokatly, Dmitry Z. Vinnitskiy, Nikolay E. Nifantiev, Kirill I. Kirgizov, Irina Zh. Shubina, Shubina, Irina Zh., Natalia Yu. Anisimova, Vera V. Reshetnikova, Reshetnikova, Vera V., Chikileva, Irina O.   +19 more
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Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium [PDF]

, 2023
Fucoidans from brown algae are described as anti-inflammatory, antioxidative, and antiangiogenic. We tested two Saccharina latissima fucoidans (SL-FRO and SL-NOR) regarding their potential biological effects against age-related macular degeneration (AMD).
Susanne Alban, Dörschmann, Philipp, Charlotte Seeba, Johann Roider, Klettner, Alexa Karina, Neupane, Sandesh, Tischhöfer, Marie-Theres, Sandesh Neupane, Philipp Dörschmann, Tabea Thalenhorst, Thalenhorst, Tabea, Marie-Theres Tischhöfer, Roider, Johann Baptist, Alban, Susanne, Seeba, Charlotte, Alexa Klettner   +15 more
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Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance

Marine Drugs, 2020
Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review
María Elena Reyes, Ismael Riquelme, Tomás Salvo, Louise Zanella, Pablo Letelier, Priscilla Brebi   +5 more
doaj   +1 more source

Physicochemical Characterization and Antitumor Activity of Fucoidan and Its Degraded Products from Sargassum hemiphyllum (Turner) C. Agardh

Molecules, 2023
Fucoidan has many biological functions, including anti-tumor activity. Additionally, it has been suggested that low-molecular-weight fucoidans have greater bioactivities.
Baozhen Luo, Zhuo Wang, Jianping Chen, Xuehua Chen, Jiarui Li, Yinghua Li, Rui Li, Xiaofei Liu, Bingbing Song, Kit-Leong Cheong, Saiyi Zhong   +10 more
doaj   +1 more source