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Fucoidans are a diverse class of sulfated polysaccharides integral to the cell wall of brown algae, and due to their various bioactivities, they are potential drugs. Standardized work with fucoidans is required for structure-function studies, but remains
Aachmann, Finn Lillelund +13 more
core +1 more source
Comparison of Fucoidans from Saccharina latissima Regarding Age-Related Macular Degeneration Relevant Pathomechanisms in Retinal Pigment Epithelium [PDF]
Fucoidans from brown algae are described as anti-inflammatory, antioxidative, and antiangiogenic. We tested two Saccharina latissima fucoidans (SL-FRO and SL-NOR) regarding their potential biological effects against age-related macular degeneration (AMD).
Susanne Alban +15 more
core +1 more source
Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance
Fucoidans are sulphated polysaccharides that can be obtained from brown seaweed and marine invertebrates. They have anti-cancer properties, through their targeting of several signaling pathways and molecular mechanisms within malignant cells. This review
María Elena Reyes +5 more
doaj +1 more source
Fucoidans from brown macroalgae (brown seaweeds) have different structures and many interesting bioactivities. Fucoidans are classically extracted from brown seaweeds by hot acidic extraction.
Thuan Thi Nguyen +9 more
doaj +1 more source
Fucoidan has many biological functions, including anti-tumor activity. Additionally, it has been suggested that low-molecular-weight fucoidans have greater bioactivities.
Baozhen Luo +10 more
doaj +1 more source
In Vitro Study of the Therapeutic Potential of Brown Crude Fucoidans in Osteoarthritis Treatment [PDF]
Osteoarthritis, one of the most common joint degenerative pathologies, still has no cure, and current treatments, such as nonsteroidal anti-inflammatory drugs, can cause serious adverse effects when taken for a long time.
Torres Pérez, María Dolores +24 more
core +1 more source
Induction of hepatocyte growth factor by fucoidan and fucoidan-derived oligosaccharides
Abstract Fucoidan, which is extracted from brown seaweed, is a complex sulphated polysaccharide that is mostly composed of l-fucose and sulphated ester groups. The structural and anionic characteristics of fucoidan are similar to those of heparin.
Kazuhiro, Fukuta, Toshikazu, Nakamura
openaire +2 more sources
In vitro and in vivo Immunoadjuvant Effects of the Enzymatically Modified Fucoidan
Objectives. No sulfated polysaccharides (fucoidans) has been declared as the pharmaceutical substances, adjuvants, etc., which is associated with the problems of obtaining the structurally characterized and homogeneous samples or their oligomeric ...
T. A. Kuznetsova +5 more
doaj +1 more source
Background Pseudomonas aeruginosa intestinal carriage rates are significantly higher in immunosuppressed individuals and hospitalized patients who therefore have increased risk of infections and antibiotic-associated diarrhea.
Rajendra Prasad Janapatla +10 more
doaj +1 more source
Fucoidans are sulphated polysaccharides that are primarily derived from brown algae and marine invertebrates. Fucoidans generally have complex structural characteristics, which contribute to their various pharmacological activities including anti-tumor ...
Haidi LIU +5 more
doaj +1 more source

