Results 131 to 140 of about 63,826 (347)

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

open access: yesThe FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher   +7 more
wiley   +1 more source

Comparative Study of Fucose, Protein, Protein Bound Fucose and Protein Bound Hexose in Sera of Hyperprolactinemia Human Female and Healthy Female

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
This study was conducted in the specialized center of endocrinology and diabetic (AlKindy hospital from June 2004 to April 2005). Sera of 80 women (include 40 diagnosed Hyperprolactinemia (HPro) and 40 healthy women as control) were used to estimate ...
W.F. Al-Taie, M. A. Al-Iqabi
doaj  

Radioactive fucose as a tool for studying glycoprotein secretion

open access: yesBrazilian Journal of Medical and Biological Research, 1998
The efficiency and reliability of radioactive fucose as a specific label for newly synthesized glycoproteins were investigated. Young adult male rabbits were injected intravitreally with [3H]-fucose, [3H]-galactose, [3H]-mannose, N-acetyl-[3H ...
A. Haddad
doaj   +1 more source

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation. [PDF]

open access: yes, 1983
We are investigating the hypothesis that carbohydrate-binding molecules on the cell surface are involved in the recirculation of lymphocytes from the bloodstream into lymphoid organs.
Rosen, SD, Stoolman, LM
core   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

open access: yesThe FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs   +7 more
wiley   +1 more source

GDP-L-fucose : synthesis and role in inflammation [PDF]

open access: yes, 2007
GDP-L-fucose: synthesis and role in inflammation The migration of leukocytes from intravascular locations to extravascular sites is essential to the immune responses.
Niittymäki, Jaana
core  

Winter‐active spiders (Clubiona) have a hyperactive antifreeze protein with a unique beta‐solenoid fold

open access: yesThe FEBS Journal, EarlyView.
Antifreeze proteins from winter‐active spiders were purified using their affinity for ice. After LC–MSMS characterization, corresponding transcripts were identified. The antifreeze protein folds as a β‐solenoid with a large flat ice‐binding site on one surface and can bind to ice crystals and prevent their growth at −4 °C.
Laurie A. Graham   +3 more
wiley   +1 more source

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