Results 71 to 80 of about 875,334 (280)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Tripling the Optical Efficiency of Color-Converted Micro-LED Displays with Funnel-Tube Array

Crystals, 2019
Color-converted micro-LED displays consist of a mono-color micro-LED array and color conversion materials to achieve full color, while relieving the burden of epitaxial growth of three-color micro-LEDs. However, it usually suffers from low efficiency and
Fangwang Gou, En-Lin Hsiang, Guanjun Tan, Yi-Fen Lan, Cheng-Yeh Tsai, Shin-Tson Wu   +5 more
doaj   +1 more source

On the Origin of [OII] Emission in Red Sequence and Post-starburst Galaxies

, 2005
We investigate the emission-line properties of galaxies with red rest-frame colors using spectra from SDSS DR4. Emission lines are detected in more than half of the red galaxies.
Binette L., David Koo, Goto T., Goudfrooij P., Heckman T. M., Jeffrey A. Newman, Marc Davis, Nicholas Konidaris, Renbin Yan, Rola C. S., S. M. Faber, Sarzi M.   +11 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Segmented cold cathode display panel [PDF]

, 1998
The present invention is a video display device that utilizes the novel concept of generating an electronically controlled pattern of electron emission at the output of a segmented photocathode.
Payne, Leslie
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Plasmonic color filters as dual-state nanopixels for high-density microimage encoding [PDF]

, 2017
Plasmonic color filtering has provided a range of new techniques for “printing” images at resolutions beyond the diffraction-limit, significantly improving upon what can be achieved using traditional, dye-based filtering methods.
Andrew, Burgos, Chen, Chen, Cheng, Chon, Clark, Cumpston, Dean, Ditlbacher, Ellenbogen, Frey, Gan, Goh, Gu, Gu, Gu, Harke, Huang, James, Kimura, Kumar, Li, Li, Li, Li, Miyata, Olson, Rajasekharan, Ren, Roberts, Shrestha, Smith, Stocker, Tan, Yokogawa, Zheng, Zheng, Zijlstra   +38 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Full-color laser displays based on organic printed microlaser arrays

Nature Communications, 2019
In the next generation of display technology for portable devices, lasers could replace LEDs to achieve more vibrant colours. Here, Zhao et al. demonstrate a dynamic full-color display in which each pixel is made up of three printed organic microlasers ...
Jinyang Zhao, Yongli Yan, Zhenhua Gao, Yuxiang Du, Haiyun Dong, Jiannian Yao, Yong Sheng Zhao   +6 more
doaj   +1 more source